Patents by Inventor Dominique J.P.M. Stumpel

Dominique J.P.M. Stumpel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapy for MLL-rearranged leukemia
    Patent number: 8859502
    Abstract: Provided are methods for treating MLL-rearranged ALL by administering to a patient an HDAC inhibitor alone or in combination with a DNA demethylating agent. Also provided are methods of treating MLL-rearranged infant ALL. Methods of treating cells by these agents are also provided. Additionally, disclosed is a method for screening for compounds capable to treat MLL-rearranged ALL, in particular, MLL-rearranged infant ALL. In one embodiment, the HDAC inhibitor is romidepsin.
    Type: Grant
    Filed: September 9, 2011
    Date of Patent: October 14, 2014
    Assignee: Celgene Corporation
    Inventors: Ronald Stam, Dominique J. P. M. Stumpel
  • THERAPY FOR MLL-REARRANGED LEUKEMIA
    Publication number: 20120094927
    Abstract: Provided are methods for treating MLL-rearranged ALL by administering to a patient an HDAC inhibitor alone or in combination with a DNA demethylating agent. Also provided are methods of treating MLL-rearranged infant ALL. Methods of treating cells by these agents are also provided. Additionally, disclosed is a method for screening for compounds capable to treat MLL-rearranged ALL, in particular, MLL-rearranged infant ALL. In one embodiment, the HDAC inhibitor is romidepsin.
    Type: Application
    Filed: September 9, 2011
    Publication date: April 19, 2012
    Inventors: Ronald STAM, Dominique J.P.M. Stumpel