Abstract: The present invention relates to the field of bio-production of ectoine. There is a need in the art for ectoine production methods allowing its highly efficient synthesis and secretion. The solution proposed in the present invention is the use of a genetically modified yeast comprising many modifications as described in the present text.

Abstract: Metabolites produced by a microorganism using oxaloacetate, pyruvate and/or acetyl-CoA as substrate or co-substrate upstream in the biosynthesis pathway, and more particularly using oxaloacetate. There is indeed a need in the art for transformed, in particular recombinant, microorganisms having at least an increased ability to produce oxaloacetate, pyruvate and/or acetyl-CoA, and in particular oxaloacetate, thus allowing an increased capacity to produce metabolites produced using oxaloacetate, pyruvate and/or acetyl-CoA as substrate or co-substrate upstream in the biosynthesis pathway, and in particular amino acids and their derivatives thereof, fatty acids, derivatives from the mevalonate pathway (in particular farnesyl, squalene, lanosterol, cholesterol and derivatives, and dolichols), flavonoides and/or polyketides. The solution proposed is the use of a genetically modified yeast comprising many modifications as described in the present text.

Abstract: A method for the bio-production of threonine including genetically modified yeasts and a method in which they are used to produce threonine, as compared to the parent yeasts.

Abstract: Metabolites produced by a microorganism using more particularly oxaloacetate as substrate or co-substrate upstream in the biosynthesis pathway. There is indeed a need in the art for transformed, in particular recombinant, microorganisms having at least an increased ability to produce oxaloacetate, thus allowing an increased capacity to produce oxaloacetate-derived amino acids and amino acid derivatives, the oxaloacetate-derived amino acids and amino acid derivatives being termed oxaloacetate derivatives. The solution is the use of a genetically modified yeast including many modifications as described in the present text.

Abstract: A method of the bio-production of methionine and/or of its derivatives thereof from a reduced source of sulfur, such as MeSH or MeSNa including genetically modified yeasts, having an increased ability to produce methionine and/or its derivatives thereof, as compared to the parent yeasts.

Abstract: The present invention relates to the field of bio-production of ectoine. There is a need in the art for ectoine production methods allowing its highly efficient synthesis and secretion. The solution proposed in the present invention is the use of a genetically modified yeast comprising many modifications as described in the present text.

Abstract: A method for the bio-production of threonine including genetically modified yeasts and a method in which they are used to produce threonine, as compared to the parent yeasts.

Abstract: Metabolites produced by a microorganism using more particularly oxaloacetate as substrate or co-substrate upstream in the biosynthesis pathway. There is indeed a need in the art for transformed, in particular recombinant, microorganisms having at least an increased ability to produce oxaloacetate, thus allowing an increased capacity to produce oxaloacetate-derived amino acids and amino acid derivatives, the oxaloacetate-derived amino acids and amino acid derivatives being termed oxaloacetate derivatives. The solution is the use of a genetically modified yeast including many modifications as described in the present text.

Abstract: A method of the bio-production of methionine and/or of its derivatives thereof from a reduced source of sulfur, such as MeSH or MeSNa including genetically modified yeasts, having an increased ability to produce methionine and/or its derivatives thereof, as compared to the parent yeasts.

Abstract: Metabolites produced by a microorganism using oxaloacetate, pyruvate and/or acetyl-CoA as substrate or co-substrate upstream in the biosynthesis pathway, and more particularly using oxaloacetate. There is indeed a need in the art for transformed, in particular recombinant, microorganisms having at least an increased ability to produce oxaloacetate, pyruvate and/or acetyl-CoA, and in particular oxaloacetate, thus allowing an increased capacity to produce metabolites produced using oxaloacetate, pyruvate and/or acetyl-CoA as substrate or co-substrate upstream in the biosynthesis pathway, and in particular amino acids and their derivatives thereof, fatty acids, derivatives from the mevalonate pathway (in particular farnesyl, squalene, lanosterol, cholesterol and derivatives, and dolichols), flavonoides and/or polyketides. The solution proposed is the use of a genetically modified yeast comprising many modifications as described in the present text.

Abstract: A recombinant yeast having a reduced pyruvate decarboxylase activity, in the génome of which has been inserted: —one or more nucleic acids encoding an acetolactate synthase or ALS, —one or more nucleic acids encoding an acetolactate decarboxylase or ALD, —one or more nucleic acids encoding a butancdiol dehydrogenase or BDH, and —one or more copies of a nucleic acids encoding a NADH oxidase or NOXE.

Abstract: The present invention relates to a recombinant yeast having a reduced pyruvate decarboxylase activity, in the genome of which has been inserted: —one or more nucleic acids encoding an acetolactate synthase or ALS, —one or more nucleic acids en coding an acetolactate decarboxylase or ALD, and—one or more copies of a nucleic acids encoding a NADH oxidase or NOXE.

Abstract: Method, source array and seismic vibro-acoustic source element for seismic data acquisition. The method includes storing in a controller a library of beam form factor sets associated with a source array and corresponding regions to be surveyed; towing the source array along survey lines over the regions to be surveyed; selecting a beam form factor set from the library to be applied to the source array for each region; and actuating the source array based on the selected set of beam form factors and a position of the source array relative to the regions. Each set of beam form factors maps to a corresponding region of an area to be surveyed.

Abstract: Method, source array and source element that generate seismic waves. The source element includes an enclosure having an opening covered by a piston; a local supply accumulator fluidly communicating with an interior of the enclosure, a pressure of the fluid inside the local supply accumulator being larger than a pressure of the fluid inside the enclosure; a local supply valve located between the local supply accumulator and the enclosure and configured to control a flow of the fluid from the local supply accumulator to the interior of the enclosure; and a controller configured to control the local supply valve such that the pressure inside the enclosure does not fall below a first preset value based upon an ambient pressure of the enclosure while seismic waves are generated.

Abstract: Provided is a method for producing L-methionine in which O-phospho-L-homoserine and methanethiol are enzymatically converted into L-methionine and H3PO4. Such a conversion is achieved by an enzyme called O-phospho-L-homoserine (OHPS) dependent methionine synthase. Also described are O-phospho-L-homoserine (OHPS) dependent methionine synthases, i.e. proteins which are able to enzymatically convert O-phospho-L-homoserine and methanethiol into L-methionine and H3PO4 as well as microorganisms which have been genetically modified so as to be able to produce L-methionine from O-phospho-L-homoserine and methanethiol. Furthermore described are methods to screen for enzymes that catalyze the conversion of O-phospho-L-homoserine and methanethiol into L-methionine and H3PO4.

Abstract: A seismic data acquisition system is configured to collect seismic data. The system includes a marine source array configured to be attached to a fixed structure floating at the water surface and including vibratory source elements; and a controller configured to control the vibratory source elements so that a beam formed by the source array is steerable.

Abstract: A recombinant yeast having a reduced pyruvate decarboxylase activity, in the génome of which has been inserted: —one or more nucleic acids encoding an acetolactate synthase or ALS, —one or more nucleic acids encoding an acetolactate decarboxylase or ALD, —one or more nucleic acids encoding a butancdiol dehydrogenase or BDH, and —one or more copies of a nucleic acids encoding a NADH oxidase or NOXE.

Abstract: The present invention relates to a recombinant yeast having a reduced pyruvate decarboxylase activity, in the genome of which has been inserted:—one or more nucleic acids encoding an acetolactate synthase or ALS,—one or more nucleic acids en coding an acetolactate decarboxylase or ALD, and—one or more copies of a nucleic acids encoding a NADH oxidase or NOXE.

Abstract: There is a method for finding a best distribution of source elements that form a vibratory source array. The method includes inputting plural constraints for the source elements; generating plural distributions of the source elements that fulfill the plural constraints; calculating for each distribution a performance index characterizing the source array; and selecting the best distribution from the plural distributions based on a value of the performance index.

Abstract: Method, source array and source element that generate seismic waves. The source element includes an enclosure having an opening covered by a piston; a local supply accumulator fluidly communicating with an interior of the enclosure, a pressure of the fluid inside the local supply accumulator being larger than a pressure of the fluid inside the enclosure; a local supply valve located between the local supply accumulator and the enclosure and configured to control a flow of the fluid from the local supply accumulator to the interior of the enclosure; and a controller configured to control the local supply valve such that the pressure inside the enclosure does not fall below a first preset value based upon an ambient pressure of the enclosure while seismic waves are generated.