Abstract: Small molecule inhibitors of salt inducible kinases (SIKs) are provided. In particular, compounds of formula (I), and tautomers, stereoisomers, pharmaceutically acceptable salts and solvates thereof are provided. Also provided are pharmaceutical compositions containing the compounds, methods of preparing the compounds, and methods of using the compounds for inhibiting SIKs, such as SIK1 and SIK2, and methods of treating diseases mediated by SIKs.

Abstract: An adjustable cover for outdoor electrical substations is disclosed. The traditional metal cover for these installations is capped with length adjustable fiberglass reinforced plastic cover pieces. The cover pieces slide over one another in an interlocking relationship to accommodate the top surfaces of a variety of existing electrical substations. Once in place the covers are maintained in the same interlocking plane to the top surface of the substation with their cooperating flanges insuring positive prevention of weather related water damage to sensitive electrical components. End caps further enhance the degree of water damage protection.

Abstract: An electrical power distribution system is provided with an elongate track and a plurality of power tap assemblies that are engageable with the track. The power tap assemblies may be moved to any desired location along the track. Power may be fed into the track through one of the assemblies and taken out of the track through another of the assemblies. Receptacles may be mounted to one or more of the power tap assemblies. A latch system can hold the power tap assemblies in (1) a fully inserted, electrically engaging orientation and (2) an electrically disconnected orientation wherein the components are still supported on the track. The components employ spring terminals which establish electrical contact through a surface-to-surface butt engagement with a conducting member. Mechanical key systems are provided for preventing improper mounting of the components on the track and for preventing the connection of more than one power in-feed to the track.

Abstract: Precipitation of salts from glycol-based fluids when mixed with water is prevented by the addition of copolymers or terpolymers of acrylic acid or alkali metal salt thereof and one or more of the monomers selected from the group consisting of 2-acrylamido-2-methylpropyl sulfonic acid or metal salt thereof, 4-styrenesulfonic acid or metal salt thereof, a lower alkyl hydroxy acrylate, and mixtures thereof.

Abstract: A luninaire adapted to be mounted at the top of a post and to direct light below a horizontal plane is disclosed. A housing element preferably of a polycarbonate material comprises a housing for an electrical system and a refractor means having an interior and exterior prismatic structure.

Abstract: A luminaire adapted to be mounted at the top of a post and to direct light below a horizontal plane is disclosed. A housing element preferably of a polycarbonate material comprises a housing for an electrical system and a refractor means having an interior and exterior prismatic structure.

Abstract: A catalyst for curing unsaturated polyester resins comprising a mixture consisting essentially of about 20 to 40% by weight of 2,5-dimethylhexane-2,5-diperoxybenzoate, about 10 to 25% by weight of tert-butyl peroxy (2-ethyl hexanoate), and about 40 to 65% by weight of tert-butylperoxy isopropyl carbonate.

Abstract: An automatic feeding hopper employs a reservoir for storing disk-like objects in a plurality of substantially horizontal rows in a substantially vertical plane. A conveyor adjoins the reservoir for engagement with a substantial portion of the lowermost row of disk-like objects in the reservoir to remove the disk-like objects from the reservoir, an exit chute is positioned adjacent the conveyor to receive the disk-like objects in a single row, and a deflecting member is positioned near the entrance to the exit chute to guide and maintain the flow of disk-like objects in a single row from the conveyor into the exit chute. The deflecting member has an upper concavely curved surface intersected by a lower curved surface which leads into a side of the exit chute, the curved surfaces meeting at an edge located a distance above the surface of the conveyor slightly more than the diameter of a disk-like object.

Abstract: Sulfide-containing scale is removed from metal surfaces by contacting the encrusted surface with an aqueous acid cleaning solution having an aldehyde (e.g., formaldehyde) dissolved or dispersed in the acid in an amount sufficient to prevent the evolution of hydrogen sulfide gas.

Abstract: A glass or plastic tube is sealed and provided with an enlarged bulb of optical clarity and minimum distortion which fits over and is spaced from the end of an endoscope.

Abstract: Apparatus for applying preprinted tubular labels or bands about the exterior of non-rigid walled containers is disclosed; the labels being made of flexible plastic and supplied from an elongated tube in a collapsed or flattened state stored in a roll supply thereof. The apparatus includes means for automatically positioning individual unlabeled containers at a labeling station and for removing labeled containers therefrom. First gripper means are provided for advancing one end of the label supply over a guide horn for opening a leading label to the general transverse configuration of the container, and for cooperation with second gripper means in detaching individual opened labels from the supply roll while advancing the opened label over the container's exterior and releasing the same at a desired location thereabout.