Abstract: Polyelectrolyte complexes between cationic polymers and anionic polymers are used in antiperspirant compositions containing an active antiperspirant ingredient.

Abstract: Polyelectrolyte complexes between cationic polymers and anionic polymers are used in antiperspirant compositions containing an active antiperspirant ingredient.

Abstract: Provided herein is a novel and useful device and method for locally delivering and controllably releasing oxybutynin in the cervical region of a female. A device of the invention comprises a ring comprising trifluoropropylmethyl/dimethyl siloxane elastomer. A pharmaceutical composition comprising oxybutynin and an excipient is placed within a bore located in the ring, wherein the bore runs from the surface of the ring into the ring. The ring has a sufficient size such that it can be inserted into the vaginal canal of a female. A cap comprising is placed over the bore at the surface of the ring in order to contain the pharmaceutical composition within the bore. When the ring is inserted into the vaginal canal, the trifluoropropylmethyl/dimethyl siloxane elastomer controllably releases and locally delivers a therapeutically effective amount of oxybutynin to the detrusor muscle to treat the female's urinary incontinence.

Abstract: Provided herein is a novel and useful device and method for locally delivering and controllably releasing oxybutynin in the cervical region of a female. A device of the invention comprises a ring comprising trifluoropropylmethyl/dimethyl siloxane elastomer. A pharmaceutical composition comprising oxybutynin and an excipient is placed within a bore located in the ring, wherein the bore runs from the surface of the ring into the ring. The ring has a sufficient size such that it can be inserted into the vaginal canal of a female. A cap comprising is placed over the bore at the surface of the ring in order to contain the pharmaceutical composition within the bore. When the ring is inserted into the vaginal canal, the trifluoropropylmethyl/dimethyl siloxane elastomer controllably releases and locally delivers a therapeutically effective amount of oxybutynin to the detrusor muscle to treat the female's urinary incontinence.

Abstract: A copolymer of p-dioxanone and a prepolymer of p-dioxanone and lactide and/or glycolide, and absorbable surgical devices such as sutures, surgical meshes, surgical staples, hemostatic clips, suture knot clips, and the like made therefrom.

Abstract: Poly(1,4-benzodioxepin-2,5-(3-H)dione), poly(1,4-benzodioxepin-2,5-(3-H, 3-methyl)dione), and copolymers of 1,4-benzodioxepin-2,5-(3-H)dione or 1,4-benzodioxepin-2,5-(3-H, 3-methyl)dione and at least one of: a) glycolide, b) (L-)lactide, c) an alkylene carbonate, d) p-dioxanone, e) e-caprolactone, f) 1,4-dioxepan-2-one, or g) 1,5-dioxepan-2-one.Surgical devices prepared from the polymers and copolymers.

Abstract: A sterile surgical suture comprising an absorbable, radiation sterilizable, normally solid polymer comprising a copolyester that comprises repeating divalent units of the formulas:(A) --O--CO--CH.sub.2 --O--CH.sub.2 CH.sub.2 --, and(B) --G--, and(C) --O--CO--CHR--O--.sub.m Ph--O--CHR--CO--O--wherein G represents the residue after removal of the hydroxyl groups of a dihydric alcohol, wherein Ph represents 1,2-, 1,3-, or 1,4-phenylene or alkyl- or alkoxy-substituted phenylene, wherein m represents a number having a value of 0 or 1, wherein R represents hydrogen or lower alkyl, and wherein the divalent units (A), (B), and (C) are bonded to each other through ester groups contained in said units.

Abstract: An absorbable, radiation sterilizable, normally solid polymer comprising a copolyester that comprises repeating divalent units of the formulas:(A) --O--CO--CH.sub.2 --O--CH.sub.2 CH.sub.2 --, and(B) --G--, and(C) --O--CO--CHR--O--.sub.m Ph--O--CHR--CO--O--wherein G represents the residue after removal of the hydroxyl groups of a dihydric alcohol, wherein Ph represents 1,2-, 1,3-, or 1,4-phenylene or alkyl- or alkoxy-substituted phenylene, wherein m represents a number having a value of 0 or 1, wherein R represents hydrogen or lower alkyl, and wherein the divalent units (A), (B), and (C) are bonded to each other through ester groups contained in said units.

Abstract: Novel flexible polyesters comprising copolymers made from an alkylene oxybenzoate and one of the following sequences: (1) an alkylene, 2-alkenyl- (or alkyl-) succinate; (2) an alkylene dimerate (from the dimer of a long chain unsaturated fatty acid), and pliant surgical products, particularly monofilament surgical sutures, therefrom.

Abstract: A copolymer of p-dioxanone and an unsubstituted or loweralkyl substituted 2,5-morpholinedione especially suited for absorbable surgical sutures and other surgical devices having accelerated absorption characteristics, but retaining good tensile strength and a high level of flexibility and softness.

Abstract: A novel family of diesters, methyl p-(.omega.-acetoxyalkoxy) benzoate wherein the alkoxy group has a chain length of 2 to 6, the method of preparation of the diesters, polymerization of the diesters and their use to form methyl p-(.omega.-hydroxy-n-alkoxy) benzoate.