Abstract: A clinical data acquisition system includes a probe and a mobile clinical viewing device communicatively coupleable to the probe. The probe includes at least one sensor that acquires physiological data of a patient. The mobile clinical viewing device includes a frame, a display, and a handle. The display is secured to a first side of the frame. The handle is secured to a second side of the frame. The handle includes a plurality of user input elements, and a user may control one or more operations of the mobile clinical viewing device by providing input via the user input elements on the handle. This allows a user to comfortably hold the mobile clinical viewing device and to control operations of the device in one hand, while the other hand is free to perform other operations such as holding the probe during examination of the patient.