Patents by Inventor Donald Low

Donald Low has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer-modified synthetic proteins
    Publication number: 20060233747
    Abstract: The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified, synthetic bioactive proteins, and of pharmaceutical compositions that contain such proteins.
    Type: Application
    Filed: June 5, 2006
    Publication date: October 19, 2006
    Applicant: Amylin Pharmaceuticals, Inc.
    Inventors: Gerd Kochendoerfer, Paolo Botti, James Bradburne, Shiah -yun Chen, Sonya Cressman, Christie Hunter, Stephen Kent, Donald Low, Jill Wilken
  • Pseudo-native chemical ligation
    Publication number: 20060149039
    Abstract: The present invention concerns methods and compositions for extending the technique of native chemical ligation to permit the ligation of a wider range of peptides, polypeptides, other polymers and other molecules via an amide bond. The invention further provides methods and uses for such proteins and derivatized proteins. The invention is particularly suitable for use in the synthesis of optionally polymer-modified, synthetic bioactive proteins, and of pharmaceutical compositions that contain such proteins.
    Type: Application
    Filed: January 27, 2006
    Publication date: July 6, 2006
    Applicant: Amylin Pharmaceuticals, Inc.
    Inventors: Christie Hunter, Paolo Botti, James Bradburne, Shiah-yun Chen, Sonya Cressman, Stephen Kent, Gerd Kochendoerfer, Donald Low