Abstract: A tissue box with disposal compartment includes a conventional compartment for the holding and dispensing of new tissues, and a second compartment for the disposal of used tissue which folds out from a side of the new tissue compartment. The used tissue disposal compartment is integrally attached to the new tissue dispensing compartment, having a common side wall therewith, and may be arranged in a folded position against the common side wall when not in use, or in an extended position for receiving used tissue. Two foldable side walls unfold into the extended position, with the fourth side wall being attached to the outer edge of the two folding side walls. A bottom wall is foldingly attached at the lower end of the common side wall so that when bent up, into the folded position, it lies against the common side wall, while in the extended position it rotates down to form the bottom of the used tissue compartment.