Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: A pressure-sensitive adhesive and a liquid crystal cell including the same are disclosed herein. In some embodiments, a pressure-sensitive adhesive having a storage elastic modulus of 700 kPa or more at a temperature of 25° C. and a frequency of 6 rad/sec, and a gel fraction of 35% or more, wherein the gel fraction is defined by Equation 1: B/A×100??[Equation 1] wherein, A is an initial mass (g) of the pressure-sensitive adhesive, B is a mass (g) of an insoluble content after the pressure-sensitive adhesive is immersed in a solvent at 60° C. for 24 hours and then dried at 150° C. for 30 minutes. The press-sensitive adhesive is advantageous for implementation into a flexible element between upper and lower substrates of a liquid crystal cell, and providing excellent electro-optical properties and appearance uniformity by minimizing defects.

Abstract: Proposed is a precursor composition for forming a metal film including a zirconium compound represented by any one of Chemical Formulas 1 to 3 and a hafnium compound represented by any one of Chemical Formulas 4 to 6.

Abstract: The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the compound according to the present disclosure, it is possible to produce an organic electroluminescent device having improved driving voltage, power efficiency, and/or lifetime properties compared to the conventional organic electroluminescent devices.

Abstract: A unit page buffer block includes first to fourth page buffer pairs. Each of the page buffer pairs includes a common column decoder block; and an upper page buffer stage and a lower page buffer stage electrically and commonly connected to the common column decoder block. Each of the upper page buffer stages includes an upper selection block; an upper latch block; and an upper cache block. Each of the lower page buffer stage includes a lower selection block; a lower latch block; and a lower cache block. Each of the upper selection blocks includes first to fourth sub-selection blocks. Each of the upper and lower latch blocks includes first to twelfth upper sub-latch blocks. Each of the upper and lower cache blocks includes first to twelfth upper sub-cache blocks. Each of the common column decoder block includes first to third sub-common column decoder blocks arranged in a row direction.

Abstract: A display device according to an exemplary embodiment includes: a substrate including a display area and a transmission area; a metal blocking layer disposed in the display area of the substrate; an inorganic insulating layer disposed on the metal blocking film; a transistor disposed on the inorganic insulating layer; an emission layer connected to the transistor; and a light blocking layer and a color filter disposed on the emission layer of the display area, wherein the edge of the light blocking layer is protruded toward the transmission area more than the edge of the metal blocking layer.

Abstract: The present invention relates to a composition for the diagnosis of a degenerative brain disease, comprising hpmA, which is a substance derived from Proteus, Shigella, Klebsiella pneumoniae, or Citrobacter, preferably a Proteus mirabilis strain, from a biological sample of a subject. In addition, the present invention relates to a method for providing information for the diagnosis of a degenerative brain disease such as Parkinson's disease, brain neuritis (neuroinflammation), or Alzheimer's disease, by measuring the amount of hpmA.

Abstract: A method for manufacturing a light modulation device is provided. The light modulation device is capable of removing defects such as orientation irregularities. The light modulation device further improves the orientation state in the light modulation device that adjusts orientation of a liquid crystal compound or the like with a liquid crystal alignment film and a pressure-sensitive adhesive layer or adhesive layer.

Abstract: Proposed is a CO2-reduction membrane electrode assembly (MEA), which is a novel MEA capable of changing a reaction condition to an alkaline condition from a problematic acidic condition unfavorable to reactions on a cathode side during catalytic reactions using a cation exchange membrane (CEM) as a separator. In addition, the MEA can reduce a hydrogen evolution reaction (HER), which is a side reaction. In addition, a method of manufacturing the MEA, and a CO2-reduction assembly including the MEA are also proposed.

Abstract: A smart drilling system includes a terminal configured to map a design space to an actual space and having perforation location information in the design space, a drilling machine including a drill for perforation and configured to perform perforation in the actual space under control of the terminal based on the perforation location information, and a total station configured to acquire location information of a reference point in the actual space for mapping the design space to the actual space and location information of the drilling machine in the actual space, and to transmit the location information of the reference point in the actual space and the location information of the drilling machine to the terminal, wherein the terminal recognizes and displays a perforable region or a perforable point at a current position of the drilling machine.

Abstract: An embodiment sulfur dioxide-based inorganic electrolyte is provided in which the sulfur dioxide-based inorganic electrolyte is represented by a chemical formula M·(A1·Cl(4-x)Fx)z·ySO2. In this formula, M is a first element selected from the group consisting of Li, Na, K, Ca, and Mg, A1 is a second element selected from the group consisting of Al, Fe, Ga, and Cu, x satisfies a first equation 0?x?4, y satisfies a second equation 0?y?6, and z satisfies a third equation 1?z?2.

Abstract: The present specification relates to a conductive structure body, a method for manufacturing the same, and an electrode and an electronic device including the conductive structure body.

Abstract: An optical device is disclosed herein. In some embodiments, a optical device includes a liquid crystal element having a top surface, a bottom surface, and sides separating the top surface and the bottom surface, and an outer layer surrounding the sides of the liquid crystal element, wherein the liquid crystal element comprises a first base layer, a second base layer, a liquid crystal layer positioned between the first base layer and the second base layer, a pressure-sensitive adhesive layer positioned between the first base layer and the liquid crystal layer, and a spacer to maintain a gap between the first base layer and the second base layer, wherein the optical device satisfies Equation 1: ?T2×0.4?T1?T2?T2×0.4??[Equation 1] wherein, T1 is a thickness of the outer layer, and T2 is a thickness of the liquid crystal element.

Abstract: The present invention relates to an apparatus and method for encoding and decoding an image by skip encoding. The image-encoding method by skip encoding, which performs intra-prediction, comprises: performing a filtering operation on the signal which is reconstructed prior to an encoding object signal in an encoding object image; using the filtered reconstructed signal to generate a prediction signal for the encoding object signal; setting the generated prediction signal as a reconstruction signal for the encoding object signal; and not encoding the residual signal which can be generated on the basis of the difference between the encoding object signal and the prediction signal, thereby performing skip encoding on the encoding object signal.

Abstract: The present invention relates to a method for preparing a sulfide-based solid electrolyte, a sulfide-based solid electrolyte prepared by the method, and an all-solid-state lithium secondary battery including the sulfide-based solid electrolyte. The method of the present invention includes a) mixing Li2S with P2S5 to prepare a mixed powder, b) placing the mixed powder, an ether, and stirring balls in a container, sealing the container, followed by stirring to prepare a suspension, and c) stirring the suspension under high-temperature and high-pressure conditions to prepare sulfide-based solid particles.

Abstract: A light modulating device is disclosed herein. The light modulating device is applied to a sunroof and/or glass of an automobile. In some embodiments, a light modulating device configured to be disposed in a sunroof of an automobile includes a light modulation film layer, wherein the light modulation film layer includes a first anisotropic substrate, a second anisotropic substrate, and a liquid crystal layer, wherein each of the first and second anisotropic substrates has a first surface, wherein the first surfaces of the first and second anisotropic substrates face each other, wherein the liquid crystal layer is disposed between the first surfaces of the first and second anisotropic substrates, and wherein a slow axis of the first or second anisotropic substrate is disposed parallel to a width direction of the automobile.

Abstract: An optical device is disclosed herein. In some embodiments, a optical device includes a liquid crystal element having a top surface, a bottom surface, and sides separating the top surface and the bottom surface, and an outer layer surrounding the sides of the liquid crystal element, wherein the liquid crystal element comprises a first base layer, a second base layer, a liquid crystal layer positioned between the first base layer and the second base layer, a pressure-sensitive adhesive layer positioned between the first base layer and the liquid crystal layer, and a spacer to maintain a gap between the first base layer and the second base layer, wherein the optical device satisfies Equation 1: ?T2×0.4?T1?T2?T2×0.4??[Equation 1] wherein, T1 is a thickness of the outer layer, and T2 is a thickness of the liquid crystal element.

Abstract: An optical device is disclosed herein. In some embodiments, an optical device includes a first outer substrate, a second outer substrate, a liquid crystal element positioned between the first outer substrate and the second outer substrate, a first intermediate layer between the first outer substrate and the liquid crystal element, and a second intermediate layer between the second outer substrate and the liquid crystal element, wherein a sum of total thicknesses of the first and second intermediate layers is 800 ?m or more, and wherein the liquid crystal element includes a first base layer, a second base layer, a liquid crystal layer between the first base layer and the second base layer, a pressure-sensitive adhesive layer between the first base layer and the liquid crystal layer, and a spacer to maintain a gap between the first and second base layers.

Abstract: A light modulating device is disclosed herein. In some embodiments, a light modulating device includes a first substrate, a second substrate, a light modulation layer, and a retardation film, wherein each of the first and second substrates has a first surface and a second surface, wherein the first and second surfaces are disposed opposite to each other, wherein the first surfaces of the first and second substrates face each other, wherein the light modulation layer is disposed between the first and second substrates, wherein the retardation film is formed on the second surface of the first substrate or the second substrate, and wherein the retardation film has an in-plane phase difference in a range of 100 nm to 300 nm for light having a wavelength of 550 nm. The light modulating device can be control omnidirectional light leakage in a black mode while having excellent optical properties and mechanical properties.

Abstract: A pressure-sensitive adhesive and a liquid crystal cell including the same are disclosed herein. In some embodiments, a pressure-sensitive adhesive having a storage elastic modulus of 700 kPa or more at a temperature of 25° C. and a frequency of 6 rad/sec, and a gel fraction of 35% or more, wherein the gel fraction is defined by Equation 1: B/A×100??[Equation 1] wherein, A is an initial mass (g) of the pressure-sensitive adhesive, B is a mass (g) of an insoluble content after the pressure-sensitive adhesive is immersed in a solvent at 60° C. for 24 hours and then dried at 150° C. for 30 minutes. The press-sensitive adhesive is advantageous for implementation into a flexible element between upper and lower substrates of a liquid crystal cell, and providing excellent electro-optical properties and appearance uniformity by minimizing defects.