Abstract: The present technology relates, in part, to long double-stranded RNA (dsRNA) (e.g., 30 or more base pairs) that inhibits gene expression.

Abstract: Provided are a photoelectrode for hydrogen generation in solar water splitting and a manufacturing method thereof. The photoelectrode for hydrogen generation in solar water splitting, includes a light absorbing layer including a chalcopyrite compound; and a hydrogen generation catalyst including CuxS (where 0?x?2) which is present on the light absorbing layer, and may be manufactured by using a solution process which enables mass production and produce hydrogen from water using sunlight with high efficiency without using a noble metal element.

Abstract: The present invention relates to a method for diagnosing pancreatic cancer using methionyl-tRNA synthetase (MRS). When used as a pancreatic cancer marker, MRS has a significantly higher level of diagnostic accuracy than conventional pancreatic cancer markers such as CEA; thus, analyzing the expression status of methionyl-tRNA synthetase (MRS) in pancreatic cells has the effect of clearly determining the presence or absence of pancreatic cancer, and said effect is likewise exhibited even in the cells that have been determined to be atypical cells by a general staining technique, and thus can be very useful in the diagnosis of pancreatic cancer.

Abstract: In various aspects and embodiments, the invention provides compounds or agents that potentiate siRNA cellular entry or activity, and provides methods for identifying such compounds or agents. Exemplary agents that act as L-type calcium channel blockers are described herein, and are shown to potentiate gene silencing with cp-asiRNAs.

Abstract: A display device including a display unit having a first region, which is flat, and second regions, which are curved, and a touch sensor layer disposed on the display unit. The touch sensor layer includes a high refractive index layer having a first refractive index and a planarization layer disposed on the high refractive index layer and having a second refractive index, which is smaller than the first refractive index, and the high refractive index layer includes pattern parts.

Abstract: A display device including a substrate, a source electrode and a drain electrode on the substrate, the source electrode and the drain electrode being spaced apart from each other, a first layer on the source electrode or the drain electrode, a second layer directly on the first layer, and a first electrode on the second layer. A step difference between a top of the first layer and a top of the drain electrode is 100 ? or less.

Abstract: In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit IL4R?, TRPA1, and/or F2RL1 expression and are therefore useful for treating atopic dermatitis or asthma.

Abstract: Provided are a basic electrocatalyst applied to a carbon dioxide reduction and ethylene production system, a basic electrocatalyst electrode and an apparatus each including the same, and a method of manufacturing the basic electrocatalyst electrode. The basic electrocatalyst electrode for for carbon dioxide reduction and ethylene production includes: catalyst particles each including copper hydroxide (Cu(OH)2); and a basic compound. Since the basic electrocatalyst electrode has high carbon dioxide reduction performance and high ethylene selectivity, the basic electrocatalyst electrode may be applied to a reduction electrode of a carbon dioxide reduction and ethylene production apparatus and may exhibit high current density and high ethylene selectivity. The basic electrocatalyst electrode may be manufactured by a simple method, and may be applied to a large-area electrode.

Abstract: The present invention relates to a gallstone solubilizing agent, comprising ursodeoxycholic acid (UDCA) or a pharmaceutically acceptable salt thereof; omega-3 fatty acid; and an excipient, the gallstone solubilizing agent resulting in a process which prevents cholesterol gallstones from being formed or causes cholesterol gallstones to be dissolved, a pharmaceutical composition comprising the same, and a health functional food composition comprising the same. A pharmaceutical composition prepared to have UDCA and omega-3 fatty acid at an optimal content ratio allows cholesterol to remain in a dissolved state without forming crystals, and thus results in a process which prevents cholesterol gallstones from being formed or causes cholesterol gallstones to be dissolved, thereby exhibiting increased effects of preventing or treating cholesterol gallstones.

Abstract: In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit CTGF expression and are therefore useful for treating idiopathic pulmonary fibrosis.

Abstract: The present invention relates to an RNAi-inducing nucleic acid molecule having a new structure and the use thereof, and more particularly to a novel nucleic acid molecule having a structure comprising a first strand, which is 24-121 nt in length and comprises a region complementary to a target nucleic acid, and a second strand which is 13-21 nt in length and has a region that binds complementarily to the region of the first strand, which is complementary to the target nucleic acid, so that the nucleic acid molecule inhibits the expression of a target gene with increased efficiency, and to a method of inhibiting the expression of a target gene using the nucleic acid molecule. The nucleic acid molecule structure of the present invention increases the efficiency with which the nucleic acid molecule inhibits the target gene.

Abstract: A chalcopyrite compound-based thin film in which an alkali metal is incorporated, and a method of fabricating the same are provided. The chalcopyrite compound-based thin film in which an alkali metal is incorporated may have improved film characteristics such as excellent chalcopyrite crystal characteristics and improved surface characteristics, and may exhibit improved optical characteristics by control of the distribution of constituent elements in the chalcopyrite compound layer. Accordingly, performance of a solar cell including the chalcopyrite compound-based thin film may be improved. The chalcopyrite compound-based thin film may be easily fabricated through a solution process.

Abstract: A display device including a substrate, a source electrode and a drain electrode on the substrate, the source electrode and the drain electrode being spaced apart from each other, a first layer on the source electrode or the drain electrode, a second layer directly on the first layer, and a first electrode on the second layer. A step difference between a top of the first layer and a top of the drain electrode is 100 ? or less.

Abstract: A display device including a display unit having a first region, which is flat, and second regions, which are curved, and a touch sensor layer disposed on the display unit. The touch sensor layer includes a high refractive index layer having a first refractive index and a planarization layer disposed on the high refractive index layer and having a second refractive index, which is smaller than the first refractive index, and the high refractive index layer includes pattern parts.

Abstract: The present invention relates to a method for diagnosis of bile duct cancer, using methionyl-tRNA synthetase (MRS) in bile duct cells of a latent patient.

Abstract: A display device including a substrate, a source electrode and a drain electrode on the substrate, the source electrode and the drain electrode being spaced apart from each other, a first planarization layer on the source electrode and the drain electrode, a second planarization layer on the first planarization layer, and a first electrode on the second planarization layer. A step difference between a top of the first planarization layer and a top of the drain electrode is 100 ? or less.

Abstract: A display device includes a substrate including a display region including a plurality of pixels and a non-display region at one side of the display region; at least one transistor on the substrate; a light emitting element connected to the transistor; a thin film encapsulation layer covering the light emitting element; a plurality of light blocking patterns on the thin film encapsulation layer, the plurality of light blocking patterns corresponding to at least a portion of a non-emission region of each pixel, and a planarization layer covering the light blocking patterns; and a touch sensor including a plurality of touch electrodes on the planarization layer. None of the light blocking patterns overlap touch electrodes.

Abstract: Electrodialysis cell systems for water deionization is provided. Also provided are methods for using the electrodialysis cell systems. The cells use the forward and reverse reactions of a redox mediator and the combined operations of a deionization cell and an ion-accumulation cell to enable sustainable deionization with a significantly decreased operating voltage, relative to conventional deionization cells. The cells have applications in seawater desalination, water purification, and wastewater treatment.

Abstract: An input sensing unit includes a base including light-transmitting areas and non-light transmitting areas. A light absorbing pattern is provided corresponding to the non-light transmitting areas and is configured to absorb incident light. A sensing electrode overlaps the light absorbing pattern. The light absorbing pattern has an aperture for exposing a light-transmitting area of the light-transmitting areas. A boundary of the aperture and an outer boundary of the light-transmitting area are spaced apart from each other. The input sensing unit has improved viewing angle/luminance ratio and improved characteristics of reflective color.

Abstract: In certain aspects, provided herein are RNA complexes (e.g., asymmetric RNA complexes, such as asiRNAs or cell penetrating asiRNAs) that inhibit ANGPT2 and/or PDGFB expression and are therefore useful for treating angiogenesis-associated diseases, such as cancer, AMD, and DME.