Patents by Inventor Dong Rim Seol

Dong Rim Seol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATION FOR DELIVERY OF LUBRICIN GENE
    Publication number: 20230001017
    Abstract: Compositions comprising nanoparticles, nanoplexes or virus comprising isolated nucleic acid comprising nucleic acid encoding a mammalian, and methods of using the compositions, are provided.
    Type: Application
    Filed: October 28, 2020
    Publication date: January 5, 2023
    Inventors: Aliasger K. Salem, James A. Martin, Leela Raghava Jaidev Chakka, Juliana c. Quarterman, Hongjun Zheng, Dong Rim Seol
  • METHODS TO PREVENT, INHIBIT OR TREAT INTERVERTEBRAL DISC DEGENERATION
    Publication number: 20220265700
    Abstract: A method to prevent, inhibit or treat intervertebral disc disease in a mammal and compositions useful in that regard are provided.
    Type: Application
    Filed: January 20, 2022
    Publication date: August 25, 2022
    Inventors: Dong Rim Seol, James A. Martin, Tae-Hong Lim, Mitchell C. Coleman, Aliasger K. Salem, Ino Song
  • METHODS OF PREVENTATIVE THERAPY FOR POST-TRAUMATIC OSTEOARTHRITIS
    Publication number: 20220233598
    Abstract: In certain embodiments, the present invention provides a method for preventing or treating post-traumatic osteoarthritis (PTOA) in the temporomandibular joint (TMJ) in a subject in need thereof, comprising administrating a pharmaceutical composition comprising an effective amount of mesenchymal stem cell-derived exosomes or mesenchymal stem cell-derived exosomal microRNA to the subject. In certain embodiments, the present invention provides a method for preventing progressive fibrocartilage degeneration in a subject in need thereof, comprising administrating a pharmaceutical composition comprising an effective amount of mesenchymal stem cell-derived exosomes or mesenchymal stem cell-derived exosomal microRNA to the subject.
    Type: Application
    Filed: January 26, 2022
    Publication date: July 28, 2022
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Kyungsup Shin, Dong Rim Seol, James A. Martin, Ino Song
  • METHODS FOR THE REGENERATION OF ARTICULAR CARTILAGE IN VIVO
    Publication number: 20180000736
    Abstract: A pharmaceutical composition is provided that is useful to enhance the repair of articular cartilage, to treat a joint injury or to prevent, inhibit or treat osteoarthritis in a mammal. The composition may include an effective amount of an isolated protein that is a chemoattractant for chondrogenic progenitor cells and/or an effective amount of an isolated protein that is a chondro genic factor or a nucleic acid sequence that encodes a chondrogenic factor.
    Type: Application
    Filed: January 7, 2016
    Publication date: January 4, 2018
    Inventors: James A. Martin, Yin Yu, Dong Rim Seol, Aliasger K Salem, Behnoush Khorsand Sourkohi, Anh-Vu T Do, Marc Brouillette