Patents by Inventor Dongsop LEE

Dongsop LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11840574
    Abstract: The present invention relates to an antibody that specifically binds to death receptor 5 (DR5) and has a function of killing cancer cells. Specifically, provided are an anti-DR5 antibody or antigen-binding fragment thereof, and a use of the antibody or antigen-binding fragment for preventing or treating cancer. The present invention is characterized in that the anti-DR5 antibody or antigen-binding fragment thereof is improved in terms of affinity to DR5, stability, and an effect of killing cancer cells.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: December 12, 2023
    Assignee: DONG-A ST CO., LTD.
    Inventors: Hyounmie Doh, Dongsop Lee, Hanyoung Lee, Yoojin Kim, Kyungmi Han, Eunee Jung, Donghyeon Kim, Eongsup Song, Kum-Joo Shin, Soyon Woo
  • Publication number: 20230133381
    Abstract: The present invention relates to an antibody that specifically binds to death receptor 5 (DR5) and has a function of killing cancer cells. Specifically, provided are an anti-DR5 antibody or antigen-binding fragment thereof, and a use of the antibody or antigen-binding fragment for preventing or treating cancer. The present invention is characterized in that the anti-DR5 antibody or antigen-binding fragment thereof is improved in terms of affinity to DR5, stability, and an effect of killing cancer cells.
    Type: Application
    Filed: February 8, 2018
    Publication date: May 4, 2023
    Inventors: Hyounmie DOH, Dongsop LEE, Hanyoung LEE, Yoojin KIM, Kyungmi HAN, Eunee JUNG, Donghyeon KIM, Eongsup SONG, Kum-Joo SHIN, Soyon WOO
  • Patent number: 9822174
    Abstract: A novel anti-vascular endothelial growth factor (VEGF) antibody having a strong binding affinity for VEGF and capable of inhibiting in vivo tumor growth and a composition for the treatment of cancer, containing the same. The antibody shows a remarkable binding property to human and mouse VEGF, suppresses the proliferation and permeability of a human umbilical vein endothelial cell (HUVEC) and inhibits tumor growth, and thus can be useful as an antibody for the treatment of cancer.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: November 21, 2017
    Assignees: DONG-A SOCIO HOLDINGS CO., LTD., DONG-A ST CO., LTD
    Inventors: Hyounmie Doh, Byong Moon Kim, Chae Young Kim, Sung-Hee Lee, Dong-Hyeon Kim, Yoo-jin Kim, Dongsop Lee, Kyung Mi Han, Dongsup Song, Eun-ee Jung, Jinseok Lee, Woo Jin Seung, Kyusang Hwang
  • Publication number: 20160122426
    Abstract: A novel anti-vascular endothelial growth factor (VEGF) antibody having a strong binding affinity for VEGF and capable of inhibiting in vivo tumor growth and a composition for the treatment of cancer, containing the same. The antibody shows a remarkable binding property to human and mouse VEGF, suppresses the proliferation and permeability of a human umbilical vein endothelial cell (HUVEC) and inhibits tumor growth, and thus can be useful as an antibody for the treatment of cancer.
    Type: Application
    Filed: May 30, 2014
    Publication date: May 5, 2016
    Applicants: DONG-A SOCIO HOLDINGS CO., LTD., DONG-A ST CO., LTD
    Inventors: Hyounmie DOH, Byong Moon KIM, Chae Young KIM, Sung-Hee LEE, Dong-Hyeon KIM, Yoo-jin KIM, Dongsop LEE, Kyung Mi HAN, Dongsup SONG, Eun-ee JUNG, Jinseok LEE, Woo Jin SEUNG, Kyusang HWANG