Abstract: The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.

Abstract: A scan driver includes: a first transistor having a first electrode coupled to an output scan line, a second electrode coupled to a first power line, and a gate electrode coupled to a first node; a second transistor having a first electrode coupled to a first clock line, a second electrode coupled to the output scan line, and a gate electrode coupled to a second node; a third transistor having a first electrode coupled to the first node, a second electrode coupled to a first input scan line, and a gate electrode coupled to a second clock line; and a fourth transistor having a first electrode coupled to the second node and a second electrode and a gate electrode, which are coupled to a second input scan line, wherein the first input scan line and the second input scan line are different from each other.

Abstract: Provided is a pharmaceutical composition for preventing or treating breast cancer including a compound derived from Dendropanax morbiferus. It was confirmed that dihydroconiferyl ferulate, a compound derived from Dendropanax morbiferus of the present disclosure, inhibited the expression of c-Myc known to be characteristically expressed in breast cancer, inhibited the mammosphere formation of breast cancer stem cells, and inhibited an EGFR signaling pathway. Accordingly, the compound inhibits the proliferation of breast cancer cells and inhibits the growth of cancer stem cells, and thus can be usefully used for prevention or treatment of breast cancer.

Abstract: A display device comprises a first substrate comprising a first contact hole, a laser absorption layer disposed on the first substrate and containing amorphous silicon, a first barrier insulating layer disposed on the laser absorption layer, fan-out lines disposed in a metal layer on the first barrier insulating layer and comprising pad portions inserted into second contact holes provided in the first barrier insulating layer and the laser absorption layer, a second barrier insulating layer disposed on the metal layer, a second substrate disposed on the second barrier insulating layer, and a display layer disposed on the second substrate. The second substrate is inserted into a third contact hole provided in the second barrier insulating layer, the first barrier insulating layer, and the laser absorption layer disposed between the pad portions.

Abstract: The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Abstract: A biosensor comprising a substrate, a gate electrode provided on the substrate, an insulating layer provided on the gate electrode, a source electrode and a drain electrode, provided on the insulating layer, respectively, an n-type channel provided between the source electrode and the drain electrode, and a quantum dot layer provided on the n-type channel and provided so as to have electronic transition energy capable of resonating with vibration energy of a target biological material.

Abstract: A gas detecting sensor including a substrate, a gate electrode provided on the substrate, an insulating layer provided on the gate electrode, a source electrode and a drain electrode, provided on the insulating layer, respectively, an n-type channel provided between the source electrode and the drain electrode, and a quantum dot layer provided on the n-type channel and provided so as to have electronic transition energy capable of resonating with vibration energy of a target gas molecule.

Abstract: A biosensor comprising a substrate, a gate electrode provided on the substrate, an insulating layer provided on the gate electrode, a source electrode and a drain electrode, provided on the insulating layer, respectively, an n-type channel provided between the source electrode and the drain electrode, and a quantum dot layer provided on the n-type channel and provided so as to have electronic transition energy capable of resonating with vibration energy of a target biological material.

Abstract: A gas detecting sensor including a substrate, a gate electrode provided on the substrate, an insulating layer provided on the gate electrode, a source electrode and a drain electrode, provided on the insulating layer, respectively, an n-type channel provided between the source electrode and the drain electrode, and a quantum dot layer provided on the n-type channel and provided so as to have electronic transition energy capable of resonating with vibration energy of a target gas molecule.

Abstract: A system for supporting the diversity of a ubiquitous computing environment according to the present invention has a message bus including a message broker managing an intermediary role of delivering an actual message between the subsystems and a messaging adaptor managing an interface function between the message broker and the subsystems, wherein the messaging adaptor is installed in the subsystems and includes a first adaptor including a first application port for interfacing with the subsystems, and a second adaptor including a second application port for interfacing with the first adaptor and the broker port operating with the message broker.

Abstract: The present invention provides a system for minimally reducing the additional development correction request of which various and diverse systems are required, in the integration platform for the ubiquitous environment construction, and for supporting the diversity of the ubiquitous computing environment which minimally reduces the burden in which developers are additionally on duty for the interface development between the subsystems for an interaction.

Abstract: The present invention discloses an apparatus for propelling the wheelchair that prevents a backward movement and helps the occupant rotate the wheel with less manual torque. The invention makes it possible for the disabled person to climb the sloped road with less manual force and without fear of dangerous backward slide.