Patents by Inventor Dong Feng Chen

Dong Feng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPY FOR GLAUCOMA AND OPTIC NEUROPATHY BY TARGETING COLONY STIMULATING FACTORS
    Publication number: 20240025986
    Abstract: The invention provides compositions and methods for treating optic neuropathic disorders.
    Type: Application
    Filed: May 16, 2023
    Publication date: January 25, 2024
    Inventors: Dong Feng Chen, Ji Min, Kin-Sang Cho
  • Composition for Controlling Neuronal Outgrowth
    Publication number: 20230277623
    Abstract: Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration.
    Type: Application
    Filed: December 2, 2022
    Publication date: September 7, 2023
    Inventors: Dong Feng Chen, Chenying Guo
  • Therapy for glaucoma and optic neuropathy by targeting colony stimulating factors
    Patent number: 11692029
    Abstract: The invention provides compositions and methods for treating optic neuropathic disorders.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: July 4, 2023
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventors: Ji Min, Kin-Sang Cho, Dong Feng Chen
  • Alpha-aminoadipate for treatment of vision loss and restoring sight
    Patent number: 11622951
    Abstract: The invention provides compositions and methods for preserving, restoring, or enhancing vision of a subject by administering compositions to an injured or diseased eye.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: April 11, 2023
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventors: Dong Feng Chen, Kin-Sang Cho
  • Modulating Neuroinflammation
    Publication number: 20220143139
    Abstract: Compositions and methods for treating and/or reducing risk of development or progression of neuroinflammation and neurodegeneration, comprising HSP60 e.g., for nasal administration, and IGFBPL1, e.g., for nasal, systemic, or ocular, e.g., intravitreal, administration.
    Type: Application
    Filed: March 3, 2020
    Publication date: May 12, 2022
    Inventors: Dong Feng Chen, Kin-Sang Cho, Min Ji
  • Therapies That Target Autoimmunity For Treating Glaucoma And Optic Neuropathy
    Publication number: 20220034903
    Abstract: The present invention comprises a composition with means to inhibit an autoimmune response and methods for using this composition to treat glaucoma and optic neuropathy.
    Type: Application
    Filed: October 18, 2021
    Publication date: February 3, 2022
    Inventors: Dong Feng Chen, Jianzhu Chen, Huihui Chen
  • Compositions for Controlling Neuronal Outgrowth
    Publication number: 20210213101
    Abstract: Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration.
    Type: Application
    Filed: October 14, 2020
    Publication date: July 15, 2021
    Inventors: Dong Feng Chen, Chenying Guo
  • ASSESSING VISUAL FUNCTION
    Publication number: 20210068650
    Abstract: Methods, systems, and devices are provided for assessing visual function, especially in animals. For example, a device can be used for assessing visual functions, such as PLR and OMR, in animals that includes a visual stimulus unit. The device can also include one or more input devices that include at least one camera that is configured to monitor movement of the test subject and a processor that is configured to analyze the movement of the test subject taken by the camera and to assess visual functions of the test subject. The device can be used in a system including a designated general location for the test subject in which the test subject can see the visual stimulus unit and move freely while being monitored by the camera.
    Type: Application
    Filed: April 3, 2019
    Publication date: March 11, 2021
    Inventors: Dong Feng Chen, Gang Luo, Cong Shi, Kin-Sang Cho
  • ALPHA-AMINOADIPATE FOR TREATMENT OF VISION LOSS AND RESTORING SIGHT
    Publication number: 20210059969
    Abstract: The invention provides compositions and methods for preserving, restoring, or enhancing vision of a subject by administering compositions to an injured or diseased eye.
    Type: Application
    Filed: August 13, 2020
    Publication date: March 4, 2021
    Inventors: Dong Feng Chen, Kin-Sang Cho
  • THERAPY FOR GLAUCOMA AND OPTIC NEUROPATHY BY TARGETING COLONY STIMULATING FACTORS
    Publication number: 20200399361
    Abstract: The invention provides compositions and methods for treating optic neuropathic disorders.
    Type: Application
    Filed: March 5, 2019
    Publication date: December 24, 2020
    Inventors: Ji Min, Kin-Sang Cho, Dong Feng Chen
  • Methods for promoting neuronal outgrowth by insulin-like growth factor binding protein-like 1 (IGFBPL-1) in glaucoma or leber's optic neuropathy
    Patent number: 10842849
    Abstract: Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: November 24, 2020
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventors: Dong Feng Chen, Chenying Guo
  • Alpha-aminoadipate for treatment of vision loss and restoring sight
    Patent number: 10780070
    Abstract: The invention provides compositions and methods for preserving, restoring, or enhancing vision of a subject by administering compositions to an injured or diseased eye.
    Type: Grant
    Filed: October 20, 2014
    Date of Patent: September 22, 2020
    Assignee: The Schepens Eye Research Institute, Inc.
    Inventors: Dong Feng Chen, Kin-Sang Cho
  • Therapies That Target Autoimmunity For Treating Glaucoma And Optic Neuropathy
    Publication number: 20190004064
    Abstract: The present invention comprises a composition with means to inhibit an autoimmune response and methods for using this composition to treat glaucoma and optic neuropathy.
    Type: Application
    Filed: July 11, 2018
    Publication date: January 3, 2019
    Applicants: The Schepens Eye Research Institute, Inc., Massachusetts Institute of Technology
    Inventors: Dong Feng Chen, Jianzhu Chen, Huihui Chen
  • Alpha-Aminoadipate For Treatment Of Vision Loss And Restoring Sight
    Publication number: 20160271091
    Abstract: The invention provides compositions and methods for preserving, restoring, or enhancing vision of a subject by administering compositions to an injured or diseased eye.
    Type: Application
    Filed: October 20, 2014
    Publication date: September 22, 2016
    Inventors: Dong Feng Chen, Kin-Sang Cho
  • Therapies That Target Autoimmunity For Treating Glaucoma And Optic Neuropathy
    Publication number: 20140147413
    Abstract: The present invention comprises a composition with means to inhibit an autoimmune response and methods for using this composition to treat glaucoma and optic neuropathy.
    Type: Application
    Filed: February 28, 2012
    Publication date: May 29, 2014
    Inventors: Dong Feng Chen, Jianzhu Chen, Huihui Chen
  • Compositions for Controlling Neuronal Outgrowth
    Publication number: 20140128322
    Abstract: Disclosed is a method of promoting neuronal growth by administering IGFBPL-1, or an agent that increases or stabilizes IGFBPL-1 activity to a subject in need thereof, e.g., a subject in need of treating optic nerve degeneration.
    Type: Application
    Filed: February 28, 2012
    Publication date: May 8, 2014
    Inventors: Dong Feng Chen, Chenying Guo
  • Methods and compositions for stimulating axon regeneration and preventing neuronal cell degeneration
    Publication number: 20030103945
    Abstract: Agents which modulate a bcl family member to control axonal growth and regeneration are described. These bcl modulating agents promote axonal growth and regeneration in the neural cells of a subject. Compositions for promoting axonal cell growth in a subject also are described. The compositions of the present invention include an effective amount of an agent which modulates a bcl family member and in a pharmaceutically acceptable carrier. Other described aspects include packaged drugs for treating a state characterized by diminished potential for axonal growth. The packaged compounds and agents also include instructions for using the agent to promote axonal growth in a subject. An exemplary agent is lithium or a salt thereof.
    Type: Application
    Filed: February 8, 2002
    Publication date: June 5, 2003
    Inventors: Dong Feng Chen, Xizhong Huang, Guang Chen, Husseini K. Manji
  • Methods of controlling axonal growth
    Publication number: 20020058613
    Abstract: Agents which modulate a bcl family member to control axonal growth and regeneration are described. These bcl modulating agents promote axonal growth and regeneration in the neural cells of a subject. Compositions for promoting axonal cell growth in a subject also are described. The compositions of the present invention include an effective amount of an agent which modulates a bcl family member and in a pharmaceutically acceptable carrier. Other described aspects include packaged drugs for treating a state characterized by diminished potential for axonal growth. The packaged compounds and agents also include instructions for using the agent to promote axonal growth in a subject.
    Type: Application
    Filed: November 1, 2001
    Publication date: May 16, 2002
    Applicant: Massachusetts Institute of Technology
    Inventors: Gerald E. Schneider, Dong Feng Chen, Susumu Tonegowa, Sonal Jhaveri