Patents by Inventor Dongmei Xu

Dongmei Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230363344
    Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.
    Type: Application
    Filed: May 22, 2023
    Publication date: November 16, 2023
    Applicant: Altria Client Services LLC
    Inventors: Andrew C. ADAMS, Marcos F. de GODOY LUSSO, Sreepriya PRAMOD, Dongmei XU
  • Patent number: 11807860
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: November 7, 2023
    Assignee: Altria Client Services LLC
    Inventors: Dongmei Xu, Chengalrayan Kudithipudi, Yanxin Shen, Jaemo Yang, Jesse Frederick, James Strickland
  • Publication number: 20230348925
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: March 13, 2023
    Publication date: November 2, 2023
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James Strickland
  • Publication number: 20230329168
    Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.
    Type: Application
    Filed: February 16, 2023
    Publication date: October 19, 2023
    Applicant: Altria Client Services LLC
    Inventors: Andrew Carl Adams, Marcos Fernando de Godoy Lusso, Sreepriya Pramod, Dongmei Xu
  • Patent number: 11767535
    Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.
    Type: Grant
    Filed: March 1, 2022
    Date of Patent: September 26, 2023
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Jaemo Yang, Yanxin Shen, Dongmei Xu, Ujwala Warek, James Strickland, Jesse Frederick
  • Patent number: 11766068
    Abstract: The method includes first adding at least one first chelator to smokeless tobacco, second adding at least one first antioxidant to the smokeless tobacco, the at least one first antioxidant being different than the at least one first chelator, and third adding at least one first flavorant to the smokeless tobacco, wherein the first adding occurs before the third adding.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: September 26, 2023
    Assignee: Altria Client Services LLC
    Inventors: Marc W. Fariss, Jeffery Edmiston, Dongmei Xu, Randall Baren, Yahya Kargalioglu, James A. Strickland
  • Publication number: 20230247961
    Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
    Type: Application
    Filed: August 22, 2022
    Publication date: August 10, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Jesse FREDERICK, Yanxin SHEN, Dongmei XU, Ujwala WAREK, James Arthur STRICKLAND
  • Patent number: 11690347
    Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: July 4, 2023
    Assignee: Altria Client Services LLC
    Inventors: Andrew C. Adams, Marcos F. de Godoy Lusso, Sreepriya Pramod, Dongmei Xu
  • Publication number: 20230203518
    Abstract: The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof.
    Type: Application
    Filed: April 13, 2022
    Publication date: June 29, 2023
    Applicant: U.S. Smokeless Tobacco Company LLC
    Inventors: Dongmei XU, Mark T. Nielsen, Yanxin Shen
  • Patent number: 11634724
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: April 25, 2023
    Assignee: Altria Client Services LLC
    Inventors: Chengalrayan Kudithipudi, Dongmei Xu, James Strickland
  • Publication number: 20230109671
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: April 2, 2020
    Publication date: April 6, 2023
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei XU, James Strickland
  • Publication number: 20230105789
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: January 26, 2021
    Publication date: April 6, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dong QI, Yanxin SHEN, Ujwala WAREK, James STRICKLAND, Dongmei XU
  • Patent number: 11602118
    Abstract: The present disclosure provides metabolic signatures and genetic markers for tracking enhanced nitrogen utilization efficiency phenotypes in tobacco plants and for introgressing enhanced nitrogen utilization efficiency phenotypes into tobacco plants. The disclosure also provides tobacco plants comprising enhanced nitrogen utilization efficiency and methods to the creation of tobacco plants comprising enhanced nitrogen utilization efficiency. The disclosure also provides recombinant polynucleotides and polypeptides for enhancing nitrogen utilization efficiency in modified tobacco plants and tobacco plants comprising the provided recombinant polynucleotides and polypeptides.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: March 14, 2023
    Assignee: Altria Client Services LLC
    Inventors: Jesse Frederick, Chengalrayan Kudithipudi, Dongmei Xu
  • Publication number: 20230035750
    Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 2, 2023
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Dongmei XU, Jesse FREDERICK, Chengalrayan KUDITHIPUDI, Yanxin SHEN, James STRICKLAND, Jaemo YANG
  • Publication number: 20220403402
    Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 22, 2022
    Applicant: Altria Client Services LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dongmei Xu, James Strickland, Yanxin Shen
  • Publication number: 20220395014
    Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.
    Type: Application
    Filed: August 22, 2022
    Publication date: December 15, 2022
    Applicant: Altria Client Services LLC
    Inventors: Yahya KARGA, James POWELL, Dongmei XU, James A. STRICKLAND, Ujwala WAREK
  • Publication number: 20220380788
    Abstract: The present disclosure provides compositions and methods related to tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
    Type: Application
    Filed: June 8, 2022
    Publication date: December 1, 2022
    Applicant: ALTRIA CLIENT SERVICES LLC
    Inventors: Chengalrayan KUDITHIPUDI, Dong QI, Yanxin SHEN, Ujwala WAREK, James A. STRICKLAND, Dongmei XU
  • Patent number: 11505530
    Abstract: Disclosed are a 1,8-naphthalimide derivative, a preparation method therefor and a use thereof. The 1,8-naphthalimide derivative is easy to prepare, and is an enhanced Cu2+ fluorescent probe, which can detect Cu2+ by two wavelengths and be applied to almost-all-water systems. According to atitration experiments and blank experiments at 392 nm and 754 nm, the detection limit of the 1,8-naphthalimide derivative of the present invention for Cu2+ is 2.6368×10?7 mol/L and 2.0156×10?7 mol/L, respectively, indicating that same can perform quantitative detection for Cu2+ with a high selectivity and a high sensitivity by using two wavelengths. In addition, a pH colorimetric switch based on 1,8-naphthalimide can rapidly and reversibly respond to a pH by means of three ways: a maximum absorption wavelength, absorbance and color change. Same has a narrow switching pH range, a good selectivity and a high sensitivity, can be used in almost-all-water systems.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: November 22, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Dongmei Xu, Yufen Chen
  • Patent number: 11457659
    Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: October 4, 2022
    Assignee: Altria Client Services LLC
    Inventors: Yahya Karga, James Powell, Dongmei Xu, James A. Strickland, Ujwala Warek
  • Patent number: 11452275
    Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: September 27, 2022
    Assignee: Altria Client Services LLC
    Inventors: Jesse Frederick, Yanxin Shen, Dongmei Xu, Ujwala Warek, James Arthur Strickland