Patents by Inventor Donna M. Ford

Donna M. Ford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030143607
    Abstract: Highly hydrophilic non-nucleosidic tags with multiple labels are provided for use in nucleic acid probes. The tags are branched structures having a phosphodiester backbone, which have the advantages of a small dimensional size and high hydrophilicity. After the tag is labeled, its high negative charge and minimal size help to keep the carriers away from DNA or RNA molecules, due to repulsion between negative charges. Non-specific intercalation and steric hindrance are therefore minimized, and the hydrophobicity, if any of reporter molecules is reduced. The probes are used in place of conventionally labeled oligonucleotides for a variety of hybridization reactions.
    Type: Application
    Filed: December 18, 2002
    Publication date: July 31, 2003
    Inventors: Guohan Yang, Donna M. Ford, Say-Jong Law, John E. Monahan, Todd B. Sells
  • Publication number: 20030097666
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Application
    Filed: May 31, 2001
    Publication date: May 22, 2003
    Inventors: Wilson O. Endege, Kathleen E. Steinmann, Jon H. Astle, Christopher C. Burgess, Eddie Carroll, Theodore J. Catino, Poornima Dwivedi, Donna M. Ford, Marcia E. Lewis, Gary A. Molino, John E. Mohahan, Robert Schlegel
  • Patent number: 6504019
    Abstract: Highly hydrophilic non-nucleosidic tags with multiple labels are provided for use in nucleic acid probes. The tags are branched structures having a phosphodiester backbone, which have the advantages of a small dimensional size and high hydrophilicity. After the tag is labeled, its high negative charge and minimal size help to keep the carriers away from DNA or RNA molecules, due to repulsion between negative charges. Non-specific intercalation and steric hindrance are therefore minimized, and the hydrophobicity, if any of reporter molecules is reduced. The probes are used in place of conventionally labeled oligonucleotides for a variety of hybridization reactions.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: January 7, 2003
    Assignee: Bayer Corporation
    Inventors: Guohan Yang, Donna M. Ford, Say-Jong Law, John E. Monahan, Todd B. Sells
  • Publication number: 20020192699
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The invention further relates to polynucleotides differentially expressed in prostate cancer.
    Type: Application
    Filed: July 23, 2002
    Publication date: December 19, 2002
    Applicant: Chiron Corporation
    Inventors: Jimmy Zhang, Jon H. Astle, Eddie Carroll, Wilson O. Endege, Donna M. Ford, John E. Monahan, Robert Schlegel, Kathleen E. Steinmann
  • Patent number: 6476207
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The invention further relates to polynucleotides differentially expressed in prostate cancer.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: November 5, 2002
    Assignee: Chiron Corporation
    Inventors: Jimmy Zhang, Jon H. Astle, Eddie Carroll, III, Wilson O. Endege, Donna M. Ford, John E. Monahan, Robert Schlegel, Kathleen E. Steinmann
  • Publication number: 20020144298
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly colon cancer cell lines and/or tissue.
    Type: Application
    Filed: June 11, 2001
    Publication date: October 3, 2002
    Inventors: Wilson O. Endege, Kathleen E. Steinmann, Jon H. Astle, Christopher C. Burgess, Steven E. Bushnell, Eddie Carroll, Theodore J. Catino, Adnan Derti, Donna M. Ford, Marcia E. Lewis, John E. Mohahan, Robert Schlegel
  • Publication number: 20020015953
    Abstract: Highly hydrophilic non-nucleosidic tags with multiple labels are provided for use in nucleic acid probes. The tags are branched structures having a phosphodiester backbone, which have the advantages of a small dimensional size and high hydrophilicity. After the tag is labeled, its high negative charge and minimal size help to keep the carriers away from DNA or RNA molecules, due to repulsion between negative charges. Non-specific intercalation and steric hindrance are therefore minimized, and the hydrophobicity, if any of reporter molecules is reduced. The probes are used in place of conventionally labeled oligonucleotides for a variety of hybridization reactions.
    Type: Application
    Filed: March 21, 2001
    Publication date: February 7, 2002
    Inventors: Guohan Yang, Donna M. Ford, Say-Jong Law, John E. Monahan, Todd B. Sells
  • Patent number: 6262333
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs. and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly colon cancer cell lines and/or tissue.
    Type: Grant
    Filed: June 8, 1999
    Date of Patent: July 17, 2001
    Assignee: Bayer Corporation
    Inventors: Wilson O. Endege, Kathleen E. Steinmann, Jon H. Astle, Christopher C. Burgess, Steven E. Bushnell, Eddie Carroll, III, Theodore J. Catino, Adnan Derti, Donna M. Ford, Marcia E. Lewis, John E. Monahan, Robert Schlegel
  • Patent number: 6262334
    Abstract: This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs, and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly in colon cancer tissue.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: July 17, 2001
    Assignee: Bayer Corporation
    Inventors: Wilson O. Endege, Kathleen E. Steinmann, Jon H. Astle, Christopher C. Burgess, Eddie Carroll, III, Theodore J. Catino, Poornima Dwivedi, Donna M. Ford, Marcia E. Lewis, Gary A. Molino, John E. Monahan, Robert Schlegel
  • Patent number: 5571039
    Abstract: This invention pertains to an abdominal support for the extended abdomen of a person who is pregnant or has a large abdomen due to obesity.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: November 5, 1996
    Inventor: Donna M. Ford
  • Patent number: 4899556
    Abstract: A removable member, having a front surface for receiving a flexible sheet of ornamental material thereover, is attachably engageable with a backing member. A peripheral edge of the sheet is gripped and held between the engaged members. The backing member carries a post, clip, pin or other device for attachment to a selected substrate such as the human body or the clothing. The movable member is held in snap engagement with the backing member for convenient separation and changeability of the ornamental sheet material.
    Type: Grant
    Filed: October 3, 1988
    Date of Patent: February 13, 1990
    Inventor: Donna M. Ford