Patents by Inventor Donovan St. Clair Green

Donovan St. Clair Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serine protease inhibitors
    Patent number: 6127340
    Abstract: This invention is directed to peptide inhibitors of serine proteases, espcecially thrombin, in which the P1-P2 natural amide linkage is replaced by another bond. Exemplary thrombin inhibitors have the formula: X-(aa.sup.3)-(aa.sup.2)-.psi.-(aa.sup.1)-Z wherein X is H or a substituent on the N-terminal amino group, aa.sup.3 is a hydrophobic amino acid, aa.sup.23 is Pro, aa.sup.1 is Arg or an Arg analgoue, Z is --COOH or a heteroatom acid group and .psi. is a non-amide linkage.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: October 3, 2000
    Assignee: Trigen Limited
    Inventors: Donovan St. Clair Green, Said Mohammed Anwr Ahmed Elgendy, Geeta Patel, Michael Finbar Scully, Christopher Andrew Goodwin, Vijay Vir Kakkar, John Joseph Deadman