Patents by Inventor Doralyn S. Dalisay

Doralyn S. Dalisay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR TREATING HYPERCHOLESTEROLEMIA AND PREPARATION METHODS THEREOF
    Publication number: 20240122880
    Abstract: The present invention relates to compositions for preventing or treating hypercholesterolemia, comprising an extract obtained from Ananas comosus, said extract comprising a therapeutically effective amount of N1, N10-Diferuloylspermidine, and preparation methods thereof. The invention provides for a natural product exhibiting HMG-CoA reductase and lipase enzyme inhibition that may be as effective as synthetic cholesterol-lowering drugs available in the market.
    Type: Application
    Filed: May 17, 2021
    Publication date: April 18, 2024
    Applicants: UNIVERSITY OF SAN AGUSTIN, DEL MONTE PHILIPPINES, INC.
    Inventors: Jonel P. SALUDES, Doralyn S. DALISAY, Angelica Faith L. SUAREZ, Angel Ann B. JUANILLO, Dave Clark D. SISON, Joey I. ORAJAY, Ma. Bella B. JAVIER
  • Hemi-phorboxazole A derivatives and methods of their use
    Patent number: 8957097
    Abstract: The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, —OH, or —C1-6alkyl; and R is —CN, a 5- or 6-membered heteroaryl, or halogen; and the pharmaceutically acceptable salt forms thereof, in addition to methods of using these compounds.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: February 17, 2015
    Assignees: The Trustees Of The University Of Pennsylvania, The Regents Of The University Of California
    Inventors: Amos B. Smith, III, Zhuqing Liu, Anne-Marie L. Hogan, Doralyn S. Dalisay, Tadeusz F. Molinski
  • HEMI-PHORBOXAZOLE A DERIVATIVES AND METHODS OF THEIR USE
    Publication number: 20130030027
    Abstract: The present invention is directed to hemi phorboxazole A: and its stereoisomers, as well as derivatives of hemi phorboxazole A of formula I: wherein ring A is aryl or a 5- or 6-membered heteroaryl optionally substituted with one or more of halogen, —OH, or —C1-6alkyl; and R is —CN, a 5- or 6-membered heteroaryl, or halogen; and the pharmaceutically acceptable salt forms thereof, in addition to methods of using these compounds.
    Type: Application
    Filed: July 23, 2010
    Publication date: January 31, 2013
    Applicants: The Regents of the University of California, The Trustes of The University of Pennsylvania
    Inventors: Amos B. Smith, III, Zhuqing Liu, Anne-Marie L. Hogan, Doralyn S. Dalisay, Tadeusz F. Molinski