Patents by Inventor DORI C. WOODS

DORI C. WOODS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR HIGH-FIDELITY SEQUENCE ANALYSIS OF INDIVIDUAL LONG AND ULTRALONG NUCLEIC ACID MOLECULES
    Publication number: 20230193353
    Abstract: Disclosed are compositions and methods related to the use of plurality of reverse transcriptase primers, unique molecular identifiers (UMIs), and/or spiky primers with unique junction identifiers to improve the sequencing and amplifications methods. In some embodiments, the disclosed methods can identify sequencing errors and PCR-jumping errors.
    Type: Application
    Filed: May 7, 2021
    Publication date: June 22, 2023
    Inventors: Zoe Fleischmann, Konstantin Khrapko, Dori C. Woods, Jonathan L. Tilly
  • Methods for growth and maturation of ovarian follicles
    Patent number: 10525086
    Abstract: The present technology provides for methods for generation and isolation of granulosa cells and/or granulosa cell precursors from multi-potent cells, wherein the granulosa cells and/or granulosa cell precursors are useful in methods for growth and maturation of follicles or follicle-like structures. Additionally, the present technology also provides for methods of increasing steroidal hormones in a subject in need thereof.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: January 7, 2020
    Assignee: Northeastern University
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • Compositions and Methods for Autologous Germline Mitochondrial Energy Transfer
    Publication number: 20190300850
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 3, 2019
    Inventors: Jonathan Lee Tilly, Dori C. Woods
  • Methods and Compositions for Ex Vivo Generation of Developmentally Competent Eggs from Germ Line Cells Using Autologous Cell Systems
    Publication number: 20160237402
    Abstract: The present technology provides for methods for the directed differentiation of multi-potent cells, female germ line stem cells, or oogonial stem cells into oocytes, granulosa cells and/or granulosa precursor cells, i.e.,“synthetic granulosa cells.” The synthetic granulosa cells are useful in methods for growth and maturation of follicles or follicle-like structures and immature oocytes. Additionally, the synthetic granulosa cells are useful in methods of increasing ovarian derived hormones and growth factors in a subject in need thereof.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 18, 2016
    Inventors: Jonathan L. TILLY, Dori C. WOODS
  • METHODS AND COMPOSITIONS FOR GENERATION OF DEVELOPMENTALLY-INCOMPETENT EGGS IN RECIPIENTS OF NUCLEAR GENETIC TRANSFER
    Publication number: 20160208214
    Abstract: The present technology provides for a developmentally-incompetent egg cell that is produced by genetically engineering (e.g., inactivating) at least one gene in an oocyte precursor cell and culturing the oocyte precursor cell in conditions sufficient to produce an egg cell. The present technology also provides for methods of using the developmentally-incompetent egg cell.
    Type: Application
    Filed: October 2, 2014
    Publication date: July 21, 2016
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • Compositions and Methods for Autologous Germline Mitochondrial Energy Transfer
    Publication number: 20150353887
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 10, 2015
    Inventors: Jonathan Lee Tilly, Dori C. Woods
  • Compositions for autologous ovarian oogonial stem cell mitochondrial energy transfer
    Patent number: 9150830
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 6, 2015
    Assignee: The General Hospital Corporation
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • Compositions and methods for autologous germline mitochondrial energy transfer
    Patent number: 8647869
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: February 11, 2014
    Assignee: The General Hospital Corporation
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • Compositions and methods for autologous germline mitochondrial energy transfer
    Patent number: 8642329
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: February 4, 2014
    Assignee: The General Hospital Corporation
    Inventors: Jonathan Lee Tilly, Dori C. Woods
  • COMPOSITIONS AND METHODS FOR AUTOLOGOUS GERMLINE MITOCHONDRIAL ENERGY TRANSFER
    Publication number: 20130060079
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Application
    Filed: August 21, 2012
    Publication date: March 7, 2013
    Applicant: The General Hospital Corporation
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • COMPOSITIONS AND METHODS FOR AUTOLOGOUS GERMLINE MITOCHONDRIAL ENERGY TRANSFER
    Publication number: 20130052727
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Application
    Filed: September 7, 2012
    Publication date: February 28, 2013
    Applicant: The General Hospital Corporation
    Inventors: Jonathan L. Tilly, Dori C. Woods
  • COMPOSITIONS AND METHODS FOR AUTOLOGOUS GERMLINE MITOCHONDRIAL ENERGY TRANSFER
    Publication number: 20120315651
    Abstract: Oogonial stem cell (OSC)-derived compositions, such as nuclear free cytoplasm or isolated mitochondria, and uses of OSC-derived compositions in autologous fertility-enhancing procedures are described.
    Type: Application
    Filed: April 13, 2012
    Publication date: December 13, 2012
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: JONATHAN L. TILLY, DORI C. WOODS