Abstract: A method for identifying and quantifying organic or biochemical substances in a fluid medium using a nanogap sensor is disclosed. A nanogap sensor with two electrodes of different materials is used, a respective probe molecule is bonded to each electrode and the free remainder of the probe molecules have at least one bondable group with specificity to a substance or analyte. The analyte has at least two binding sites and passes selectively out of the fluid medium, binds to the free ends of the probe molecules to form a bridge, modifying the impedance between the electrodes.

Abstract: A method for identifying and quantifying organic or biochemical substances in a fluid medium using a nanogap sensor is disclosed. A nanogap sensor with two electrodes of different materials is used, a respective probe molecule is bonded to each electrode and the free remainder of the probe molecules have at least one bondable group with specificity to a substance or analyte. The analyte has at least two binding sites and passes selectively out of the fluid medium, binds to the free ends of the probe molecules to form a bridge, modifying the impedance between the electrodes.

Abstract: A biocompatible porous scaffolds, especially bone regeneration scaffolds, comprising carbon-based nanoparticles, especially diamond nanoparticles, methods for the production of such biocompatible porous scaffolds, the use of such biocompatible porous scaffolds and methods for treating bone defects by inserting such biocompatible porous scaffolds comprising carbon-based nanoparticles into the bone defect.

Abstract: A base body contains a substrate that is at least partially coated with a carbon-containing layer. The carbon-containing layer is at least partially functionalized with a molecule that is bound directly or via at least one linker or functional group to the carbon-containing layer. The base body, which has a functionalized carbon-containing surface, is capable of influencing biological processes during a corresponding functionalization.

Abstract: Method for coating micromechanical components of a micromechanical system, in particular a watch movement, comprising: providing a substrate (4) component to be coated; providing said component with a first diamond coating (2) doped with boron; providing said component with a second diamond coating (3); wherein: said second diamond coating (3) is provided by CVD in a reaction chamber; during CVD deposition, during the last portion of the growth process, a controlled increase of the carbon content within the reaction chamber is provided, thereby providing an increase of the sp2/sp3 carbon (6) bonds up to an sp2 content substantially between 1% and 45%. Corresponding micromechanical components are also provided.

Abstract: Method for coating micromechanical components of a micromechanical system, in particular a watch movement, comprising: providing a substrate component to be coated; providing said component with a diamond coating; wherein said diamond coating conductivity is increased in order to reduce dust attraction by the coated component when used in said micromechanical system. Corresponding micromechanical components and systems are also provided.

Abstract: The invention relates to a method for identifying organic or biochemical substances and for determining their concentration in a fluid medium using a nanogap sensor that comprises at least two electrodes. The invention is characterized in that: a nanogap sensor) with electrodes of different materials is used, a respective probe molecule is bonded to each surface of the two electrodes of the sensor and the free remainder of the probe molecules have at least one bondable group with specificity for bonding to a sought substance or to an analyte molecule in the fluid medium. The analyte molecule has at least two binding sites and passes selectively out of the fluid medium in which it is contained, binds to the free ends of the probe molecules, forming a bridge with the probe molecule, and modifies the resulting impedance between the electrodes. The concentration of the substance in the fluid medium can be determined as a result of the modification.