Patents by Inventor Doron Amit

Doron Amit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Constructs containing multiple expression cassettes for cancer therapy
    Patent number: 10004813
    Abstract: The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: June 26, 2018
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Avraham Hochberg, Doron Amit
  • CONSTRUCTS CONTAINING MULTIPLE EXPRESSION CASSETTES FOR CANCER THERAPY
    Publication number: 20160015834
    Abstract: The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
    Type: Application
    Filed: September 30, 2015
    Publication date: January 21, 2016
    Inventors: Avraham HOCHBERG, Doron AMIT
  • Diphtheria toxin first open reading frame operably linked to an H19 promoter and a diphtheria toxin second open reading frame operably linked to an IGF-II promoter as nucleic acid construct
    Patent number: 9173964
    Abstract: The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: November 3, 2015
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Avraham Hochberg, Doron Amit
  • CONSTRUCTS CONTAINING MULTIPLE EXPRESSION CASSETTES FOR CANCER THERAPY
    Publication number: 20100256225
    Abstract: The present invention relates to the field of cancer treatment, particularly to a novel constructs useful for treating tumors expressing H19 and/or IGF-II. More specifically, the invention provides compositions and methods utilizing a nucleic acid construct enabling expression of a cytotoxic gene product directed by more than one tumor specific promoter.
    Type: Application
    Filed: October 23, 2008
    Publication date: October 7, 2010
    Inventors: Avraham Hochberg, Doron Amit