Patents by Inventor Dorothy French

Dorothy French has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for diagnosis and treatment of hepatic cancers
    Patent number: 10266602
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: April 23, 2019
    Assignee: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • Methods of treating liver conditions using Notch2 antagonists
    Patent number: 10208114
    Abstract: Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2 antibodies. Liver conditions include, but are not limited to, chronic liver disease.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: February 19, 2019
    Inventors: Dorothy French, Christian W. Siebel, Erik Huntzicker
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF HEPATIC CANCERS
    Publication number: 20180355054
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Application
    Filed: April 27, 2018
    Publication date: December 13, 2018
    Applicant: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • METHODS OF TREATING FGFR3 RELATED CONDITIONS
    Publication number: 20180194844
    Abstract: Provided herein are biomarkers and therapies for the treatment of pathological conditions, such as cancer, and method of using FGFR3 antagonists. In particular, provided is FGFR3 as a biomarker for patient selection and prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
    Type: Application
    Filed: October 19, 2017
    Publication date: July 12, 2018
    Applicant: Genentech, Inc.
    Inventor: Dorothy French
  • Anti-JAG1 antibody compositions and methods for treatment of hepatic cancers
    Patent number: 9982058
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: May 29, 2018
    Assignee: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • METHODS OF USING FGF19 MODULATORS
    Publication number: 20170342488
    Abstract: Provided herein are methods of using FGF19 modulators and/or bile acid metabolism biomarkers.
    Type: Application
    Filed: May 30, 2017
    Publication date: November 30, 2017
    Applicant: Genentech, Inc.
    Inventors: Rama PAI, Donna M. Dambach, Dorothy French, Veronique V. Lauriault
  • METHODS OF TREATING LIVER CONDITIONS USING NOTCH2 ANTAGONISTS
    Publication number: 20170327574
    Abstract: Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2 antibodies. Liver conditions include, but are not limited to, chronic liver disease.
    Type: Application
    Filed: April 25, 2017
    Publication date: November 16, 2017
    Applicant: Genentech, Inc.
    Inventors: Dorothy French, Christian W. Siebel, Erik Huntzicker
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF HEPATIC CANCERS
    Publication number: 20170210815
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Application
    Filed: December 8, 2016
    Publication date: July 27, 2017
    Applicant: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • Methods of treating liver conditions using Notch2 antagonists
    Patent number: 9663573
    Abstract: Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2 antibodies. Liver conditions include, but are not limited to, chronic liver disease.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: May 30, 2017
    Assignee: GENENTECH, INC.
    Inventors: Dorothy French, Christian W. Siebel, Erik Huntzicker
  • Compositions and methods for diagnosis and treatment of hepatic cancers
    Patent number: 9550829
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 24, 2017
    Assignee: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • ANTI-FGFR4 ANTIBODIES AND METHODS OF USE
    Publication number: 20160237157
    Abstract: The invention provides anti-FGFR4 antibodies and methods of using the same.
    Type: Application
    Filed: January 13, 2016
    Publication date: August 18, 2016
    Inventors: Mark DENNIS, Luc DESNOYERS, Dorothy FRENCH
  • METHODS OF TREATING FGFR3 RELATED CONDITIONS
    Publication number: 20160185864
    Abstract: Provided herein are biomarkers and therapies for the treatment of pathological conditions, such as cancer, and method of using FGFR3 antagonists. In particular, provided is FGFR3 as a biomarker for patient selection and prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
    Type: Application
    Filed: July 30, 2015
    Publication date: June 30, 2016
    Applicant: GENENTECH, INC.
    Inventor: Dorothy FRENCH
  • Anti-FGFR4 antibodies and methods of use
    Patent number: 9266955
    Abstract: The invention provides anti-FGFR4 antibodies and methods of using the same.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: February 23, 2016
    Assignee: Genentech, Inc.
    Inventors: Mark Dennis, Luc Desnoyers, Dorothy French
  • IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
    Publication number: 20150266953
    Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
    Type: Application
    Filed: December 23, 2014
    Publication date: September 24, 2015
    Applicant: GENENTECH, INC.
    Inventors: Jian CHEN, Ellen FILVAROFF, Sherman FONG, Dorothy FRENCH, Audrey GODDARD, Paul J. GODOWSKI, J. Christopher GRIMALDI, Austin L. GUMEY, Kenneth J. HILLAN, Sarah G. HYMOWITZ, Hanzhong LI, James Pan ZTUBICOKE, Melissa A. STAROVASNIK, Daniel TUMAS, Menno VAN LOOKEREN, Richard VANDLEN, Colin K. WATANABE, P. Mickey WILLIAMS, William I. WOOD, Daniel G. YANSURA
  • IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
    Publication number: 20150141283
    Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
    Type: Application
    Filed: September 17, 2014
    Publication date: May 21, 2015
    Applicant: GENENTECH, INC.
    Inventors: Jian CHEN, Ellen FILVAROFF, Sherman FONG, Dorothy FRENCH, Audrey GODDARD, Paul J. GODOWSKI, J. Christopher GRIMALDI, Austin L. GURNEY, Kenneth J. HILIAN, Sarah G. HYMOWITZ, Hanzhong LI, Melissa A. STAROVASNIK, Daniel TUMAS, Menno VAN LOOKEREN, Richard VANDLEN, Colin K. WATANABE, P. Mickey WILLIAMS, William I. WOOD, Daniel G. YANSURA, James PAN
  • METHODS OF TREATING LIVER CONDITIONS USING NOTCH2 ANTAGONISTS
    Publication number: 20150064186
    Abstract: Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2 antibodies. Liver conditions include, but are not limited to, chronic liver disease.
    Type: Application
    Filed: April 6, 2012
    Publication date: March 5, 2015
    Applicant: GENENTECH, INC.
    Inventors: Dorothy French, Christian W. Siebel, Erik Huntzicker
  • COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF HEPATIC CANCERS
    Publication number: 20140314749
    Abstract: The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided.
    Type: Application
    Filed: March 13, 2014
    Publication date: October 23, 2014
    Applicant: Genentech, Inc.
    Inventors: Dorothy French, Erik Huntzicker, Christian W. Siebel
  • ANTI-FGFR4 ANTIBODIES AND METHODS OF USE
    Publication number: 20140037624
    Abstract: The invention provides anti-FGFR4 antibodies and methods of using the same.
    Type: Application
    Filed: October 4, 2013
    Publication date: February 6, 2014
    Applicant: GENENTECH, INC.
    Inventors: Mark Dennis, Luc Desnoyer, Dorothy French
  • METHODS OF TREATING FGFR3 RELATED CONDITIONS
    Publication number: 20140030259
    Abstract: Provided herein are biomarkers and therapies for the treatment of pathological conditions, such as cancer, and method of using FGFR3 antagonists. In particular, provided is FGFR3 as a biomarker for patient selection and prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
    Type: Application
    Filed: July 26, 2013
    Publication date: January 30, 2014
    Applicant: Genentech, Inc.
    Inventor: Dorothy French
  • METHODS OF TREATING LIVER CONDITIONS USING NOTCH2 ANTAGONISTS
    Publication number: 20130089562
    Abstract: Methods and compositions for the treatment of liver conditions are provided, such methods and compositions comprising Notch2 antagonists, e.g., anti-Notch2 antibodies. Liver conditions include, but are not limited to, chronic liver disease.
    Type: Application
    Filed: April 6, 2012
    Publication date: April 11, 2013
    Inventors: Dorothy French, Christian W. Siebel, Erik Huntzicker