Patents by Inventor Dorte Bjerre Steensgaard

Dorte Bjerre Steensgaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220202909
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 30, 2022
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Publication number: 20200384088
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Application
    Filed: August 4, 2020
    Publication date: December 10, 2020
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Patent number: 10596231
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: March 24, 2020
    Assignee: Novo Nordisk A/S
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Publication number: 20190183979
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Application
    Filed: February 20, 2019
    Publication date: June 20, 2019
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Patent number: 10265385
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analog, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: April 23, 2019
    Assignee: Novo Nordisk A/S
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Publication number: 20180303908
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Application
    Filed: June 29, 2018
    Publication date: October 25, 2018
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Publication number: 20180169190
    Abstract: The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue, and to the medical use of such compositions for basal insulin administration therapy.
    Type: Application
    Filed: December 15, 2017
    Publication date: June 21, 2018
    Inventors: Mathias Norrman, Susanne Hostrup, Dorte Bjerre Steensgaard, Holger Martin Strauss, Rosa Rebecca Erritzoee Hansen, Svend Havelund, Morten Schlein, Jesper Soendergaard Pedersen
  • Patent number: 9481721
    Abstract: A stable pharmaceutical formulation containing an insulin derivative can conveniently be prepared by adding glycerol, phenol, m-cresol and zinc ions to it.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: November 1, 2016
    Assignee: Novo Nordisk A/S
    Inventors: Helle Naver, Morten Schlein, Dorte Bjerre Steensgaard, Ingrid Vivika Petterson
  • Patent number: 9034818
    Abstract: The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: May 19, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Christian Poulsen, Kasper Huus, Frantisek Hubalek, Dorte Bjerre Steensgaard, Svend Havelund
  • Publication number: 20150126442
    Abstract: A stable pharmaceutical formulation containing an insulin derivative can conveniently be prepared by adding glycerol, phenol, m-cresol and zinc ions to it.
    Type: Application
    Filed: April 5, 2013
    Publication date: May 7, 2015
    Applicant: NOVO NORDISK A/S
    Inventors: Helle Naver, Morten Schlein, Dorte Bjerre Steensgaard, Ingrid Vivika Petterson
  • Patent number: 8937042
    Abstract: Pharmaceutical composition for parenteral administration comprising a basal insulin peptide and an insulinotropic GLP-1 peptide comprising at least 6 zinc atoms per 6 insulin molecules.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: January 20, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Anne Plum, Dorte Bjerre Steensgaard, Jens Kaalby Thomsen, Morten Schlein, Anne Sofie Kajær Markussen, Christian Poulsen
  • Publication number: 20110152185
    Abstract: Pharmaceutical composition for parenteral administration comprising a basal insulin peptide and an insulinotropic GLP-1 peptide comprising at least 6 zinc atoms per 6 insulin molecules.
    Type: Application
    Filed: November 14, 2008
    Publication date: June 23, 2011
    Applicant: Novo Nordisk A/S
    Inventors: Anne Plum, Dorte Bjerre Steensgaard, Jens Kaalby Thomsen, Morten Schlein, Anne Sofie Kajaer Markussen, Christian Poulsen
  • Patent number: 7879893
    Abstract: The present invention relates to novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer having the formula A-B-C-D-X (III), wherein: A is a chemical group which reversibly binds to a HisB10 Zn2+ sites of an insulin hexamer; B is a linker; C is a fragment consisting of 0 to 5 neutral amino acids; D is a fragment comprising 1 to 20 positively charged groups independently selected from amino or guanidino groups; and X is —OH, —NH2 or a diamino group. The present invention also relates to R-state insulin hexamers comprising such ligands, and aqueous insulin preparations comprising such R-state insulin hexamers.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: February 1, 2011
    Assignee: Novo Nordisk A/S
    Inventors: Helle Birk Olsen, Niels C. Kaarsholm, Peter Madsen, Soren Ostergaard, Svend Ludvigsen, Palle Jakobsen, Anders Klarskov Petersen, Dorte Bjerre Steensgaard
  • Publication number: 20100167990
    Abstract: The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation.
    Type: Application
    Filed: June 12, 2008
    Publication date: July 1, 2010
    Applicant: NOVO NORDISK A/S
    Inventors: Christian Poulsen, Kasper Huus, Frantisek Hubalek, Dorte Bjerre Steensgaard, Sven Havelund
  • Publication number: 20030229120
    Abstract: Novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer that are capable of prolonging the action of insulin preparations are disclosed.
    Type: Application
    Filed: May 14, 2003
    Publication date: December 11, 2003
    Inventors: Helle Birk Olsen, Niels C. kaarsholm, Peter Madsen, Soren Ostergaard, Svend Ludvigsen, Palle Jakobsen, Anders Klarskov Petersen, Dorte Bjerre Steensgaard