Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

Abstract: The present disclosure provides a compound represented by structural Formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: Novel semiconductor devices are taught. The novel devices include a thin film transistor (TFT) with an n-type semiconductor layer to form a channel between a source and a drain. The TFT further includes a source-channel interfacial member adjacent to at least the source contact of the device to provide depletion layer control of the operation of the TFT.

Abstract: A method for controlling a robotic system includes determining a location and/or a pose of a power system component based on data received from one or more sensors, and determining a mapping of a location of a robotic system within a model of an external environment of the robotic system based on the data. The model of the external environment provides locations of objects external to the robotic system. A sequence of movements of components of the robotic system is determined to perform maintenance on the power system component based on the locations of the objects external to the robotic system and/or the location or pose of the power system component. One or more control signals are communicated to remotely control movement of the components of the robotic system based on the sequence or movements of the components to perform maintenance on the power system component.

Abstract: The present disclosure provides a compound represented by structural Formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: A non-pneumatic tire is provided that has a hub with a central axis. A supporting structure is located outward from the hub in a radial direction, and a shear band is located outward from the supporting structure in the radial direction. Tread is located outward from the shear band in the radial direction. A static discharge element extends from a first radial end of the supporting structure to a second radial end of the supporting structure. The first radial end is located closer to the central axis than the second radial end in the radial direction. The static discharge element is electrically conductive to conduct electricity through the supporting structure.

Abstract: There is provided a computer-implemented method comprising, at an intermediary process acting as an intermediary between a publisher system and a plurality of subscriber processes, the intermediary process having a publisher data store storing one or more subscriptions for which the intermediary process is a publisher and a subscriber data store storing one or more subscriptions for which the intermediary process is a subscriber.

Abstract: Compounds and compositions useful for treating disorders related to mutant KIT are described herein.

Abstract: The present disclosure provides a compound represented by structural Formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: A telescoping mirror pivot assembly comprises a telescoping frame assembly, a central shaft, and a mirror head. The telescoping frame assembly may include a first end and a second end. The central shaft may be coupled to the first end of the telescoping frame assembly. The central shaft may include a detent manual fold arm. The detent manual fold arm may comprise a first detent and a second detent. The first detent may be configured to mechanically secure the telescoping frame assembly in a first position. The second detent may be configured to mechanically secure the telescoping frame assembly in a second position. The mirror head may be coupled to the second end of the telescoping frame assembly. The telescoping frame assembly may be configured to transition from the first position to the second position when a first force is applied in a first direction to the mirror head.

Abstract: The present disclosure provides a compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: A power telescoping mirror pivot assembly includes a base frame, a first telescoping arm and a second telescoping arm, wherein the first telescoping arm is pivotally attached at its first end of the base frame and the second telescoping arm is pivotally attached at its first end to the base frame, a telescoping frame assembly comprising a telescoping motor, wherein the telescoping motor is mounted to the telescoping frame assembly and is attached at a second end of the first telescoping arm and at a second end of the second telescoping arms, and a mirror head attached to the telescoping frame assembly.

Abstract: The present disclosure provides a compound represented by structural Formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: Compounds and compositions useful for treating disorders related to mutant KIT are described herein.

Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.

Abstract: The present disclosure provides a compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: The present disclosure provides a compound represented by structural formula (I): or a pharmaceutically acceptable salt thereof useful for treating a cancer.

Abstract: Systems and methods for medical data aggregation, transformation, and presentation are provided. In one example, a method comprises sets of attributes and supplementary attributes are selectively presented as directly editable medical notes in an interface with enhanced functionality.

Abstract: Provided herein are co-crystal forms comprising 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (VX-745): and compositions thereof, useful as inhibitors of one or more protein kinases and which exhibit desirable characteristics for the same.

Abstract: Described herein are compounds that inhibit ALK2 and its mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.