Abstract: Methods and systems for detecting and quantifying signal peaks from ESI-TOF-MS data may include creating a signal model and a noise model for mass spectrometry (MS) data. The method may also include detecting a signal peak based, at least in part, on the signal model and the noise model for the MS data. The method may further include determining an amplitude of the detected signal peak based, at least in part, on the signal model and the noise model for the MS data.

Abstract: A method for preparing an organic pigment dispersion, such as a flush pigment or ink product, comprises steps of introducing into a twin screw extruder a stable, water-borne pigment dispersion, an organic medium, and a destabilizing agent; mixing together the stable, water-borne pigment dispersion, the organic medium, and the destabilizing agent to produce a pigment flush phase and a water phase; and removing at least a part of the water phase. A twin-screw extruder for carrying out the flushing method has an addition and flushing zone, a water removal zone, and a zone for rinsing the crude organic pigment dispersion or flush with water and removing the rinse water. Additional materials may be added to form a finished pigmented product such as an ink product, masterbatch, or toner.