Patents by Inventor Douglas E. Raines
Douglas E. Raines has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10154991Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: GrantFiled: October 19, 2017Date of Patent: December 18, 2018Assignee: Annovation Biopharma, Inc.Inventors: Douglas E. Raines, Syed Shaukat Husain, John C. R. Randle
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Publication number: 20180098968Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: ApplicationFiled: October 19, 2017Publication date: April 12, 2018Applicants: THE GENERAL HOSPITAL CORPORATION, ANNOVATION BIOPHARMA, INC.Inventors: Douglas E. RAINES, Syed Shaukat HUSAIN, John C.R. RANDLE
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Patent number: 9820971Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: GrantFiled: November 10, 2016Date of Patent: November 21, 2017Assignees: THE GENERAL HOSPITAL CORPORATION, ANNOVATION BIOPHARMA, INC.Inventors: Douglas E. Raines, Syed Shaukat Husain, John C. R. Randle
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Publication number: 20170273951Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: ApplicationFiled: November 10, 2016Publication date: September 28, 2017Applicants: THE GENERAL HOSPITAL CORPORATION, ANNOVATION BIOPHARMA, INC.Inventors: Douglas E. RAINES, Syed Shaukat HUSAIN, John C.R. RANDLE
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Patent number: 9522136Abstract: Provided herein are compounds according to formula (I): provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: GrantFiled: July 24, 2015Date of Patent: December 20, 2016Assignees: THE GENERAL HOSPITAL CORPORATION, ANNOVATION BIOPHARMA, INC.Inventors: Douglas E. Raines, Syed Shaukat Husain, John C. R. Randle
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Publication number: 20150328189Abstract: Provided herein are compounds according to formula (I): provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: ApplicationFiled: July 24, 2015Publication date: November 19, 2015Applicants: ANNOVATION BIOPHARMA, LLC., THE GENERAL HOSPITAL CORPORATIONInventors: Douglas E. RAINES, Syed Shaukat HUSAIN, John C.R. RANDLE
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Patent number: 9187421Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; R4 and R5 are independently H, halogen, CN or CF3; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: GrantFiled: May 19, 2014Date of Patent: November 17, 2015Assignees: THE GENERAL HOSPITAL CORPORATION, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Douglas E. Raines, Joseph F. Cotten, Stuart A. Forman, Keith W. Miller, Syed S. Husain, Gregory D. Cuny
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Patent number: 9181197Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: GrantFiled: September 13, 2013Date of Patent: November 10, 2015Assignee: THE GENERAL HOSPITAL CORPORATIONInventors: Douglas E. Raines, Stuart A. Forman, Keith W. Miller, Syed Shaukat Husain, Joseph F. Cotten
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Patent number: 9156825Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: GrantFiled: January 11, 2013Date of Patent: October 13, 2015Assignees: THE GENERAL HOSPITAL CORPORATION, ANNOVATION BIOPHARMA, LLCInventors: Douglas E. Raines, Syed Shaukat Husain, John C. R. Randle
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Publication number: 20150203476Abstract: Provided herein are compounds according to formula (I): Provided herein is also a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and a method for providing anesthesia in a subject by administering such a pharmaceutical composition.Type: ApplicationFiled: January 11, 2013Publication date: July 23, 2015Inventors: Douglas E. Raines, Syed Shaukat Husain, John C.R. Randle
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Publication number: 20150011603Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; R4 and R5 are independently H, halogen, CN or CF3; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: ApplicationFiled: May 19, 2014Publication date: January 8, 2015Applicants: THE GENERAL HOSPITAL CORPORATION, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.Inventors: Douglas E. RAINES, Joseph F. COTTEN, Stuart A. FORMAN, Keith W. MILLER, Syed S. HUSAIN, Gregory D. CUNY
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Publication number: 20140200251Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: ApplicationFiled: September 13, 2013Publication date: July 17, 2014Applicant: THE GENERAL HOSPITAL CORPORATIONInventors: Douglas E. Raines, Stuart A. Forman, Keith W. Miller, Syed Shaukat Husain, Joseph F. Cotten
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Patent number: 8765973Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; R4 and R5 are independently H, halogen, CN or CF3; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: GrantFiled: July 8, 2010Date of Patent: July 1, 2014Assignee: The General Hospital CorporationInventors: Douglas E. Raines, Joseph F. Cotten, Stuart A. Forman, Keith W. Miller, Syed S. Husain, Gregory D. Cuny
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Patent number: 8557856Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: GrantFiled: March 31, 2009Date of Patent: October 15, 2013Assignee: The General Hospital CorporationInventors: Douglas E. Raines, Stuart A. Forman, Keith W. Miller, Syed Shaukat Husain, Joseph F. Cotten
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Publication number: 20130079381Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; R4 and R5 are independently H, halogen, CN or CF3; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: ApplicationFiled: July 8, 2010Publication date: March 28, 2013Inventors: Douglas E. Raines, Joseph F. Cotten, Stuart A. Forman, Keith W. Miller, Syed S. Husain, Gregory D. Cuny
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Publication number: 20110053998Abstract: The invention is directed to compounds according to formula (I): where R1 is L1C(O)OT or L1C(O)OL2C(O)OT; R2 is a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, or R1; n is an integer from 0 to 5; each R3 is independently halogen or R2; L1 and L2 are each independently a bond, a substituted or unsubstituted C1-C10 alkylene, C2-C10 alkenylene, or C2-C10 alkynylene; and T is H, a substituted or unsubstituted C1-C10 alkyl, C2-C10 alkenyl, or C2-C10 alkynyl, nitrophenol, or cyclopropyl. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier, and to methods for providing anesthesia in mammals by administering such a pharmaceutical composition.Type: ApplicationFiled: March 31, 2009Publication date: March 3, 2011Applicant: THE GENERAL HOSPITAL CORPORATIONInventors: Douglas E. Raines, Stuart A. Forman, Keith W. Miller, Syed Shaukat Husain, Joseph F. Cotten