Patents by Inventor Douglas L. Vizard

Douglas L. Vizard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7011945
    Abstract: A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of micro-spheres dispersed in a fluid containing a gelling agent or a precursor to a gelling agent and immobilized at random positions on the substrate, at least one sub-population of said population micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a nucleic acid probe sequence; contacting said array with a target nucleic acid sequence; and detecting the color barcode of said sub-population of micro-spheres due to the interaction of said probe nucleic acid sequence and said target nucleic acid sequence.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: March 14, 2006
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Patent number: 6947142
    Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, at least one of which has a color characteristic; capturing the microarray with an electronic color image sensor assembly having a matrix of pixels to produce an electronic microarray image; detecting the location of a microsphere within the captured microarray image; and identifying a color characteristic of the detected microsphere.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: September 20, 2005
    Assignee: Eastman Kodak Company
    Inventors: Samuel Chen, Krishnan Chari, Martin C. Kaplan, Douglas L. Vizard, Joaquin Calcines
  • Patent number: 6916620
    Abstract: A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of nucleic acid probe modified micro-spheres immobilized in a coating containing a gelling agent or a precursor to a gelling agent, wherein a first portion of the micro-spheres is submerged in the gelatin coating and a second portion is exposed above the gelatin coating and is substantially free of gelatin, at least one sub-population of the population micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a nucleic acid probe sequence; contacting the array with a target nucleic acid sequence; and detecting the color barcode of the sub-population of micro-spheres due to the interaction of the probe nucleic acid sequence and the fluorescently/chemiluminescently labeled nucleic acid sample target nucleic acid sequence.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: July 12, 2005
    Assignee: Eastman Kodak Company
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Publication number: 20040265905
    Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, including at least one colored microsphere which has a color characteristic; producing a magnified optical image of individual microspheres of the microarray; locating a microsphere in the aperture of a spectrometer to confine the color region of interest of the located microsphere in order to determine one or more color characteristics thereof; and determining one or more color characteristics of the located microsphere by means of the spectrometer.
    Type: Application
    Filed: June 26, 2003
    Publication date: December 30, 2004
    Inventors: Samuel Chen, Anthony E. Taddei, Joaquin Calcines, Krishnan Chari, Martin C. Kaplan, Douglas L. Vizard
  • Publication number: 20040263848
    Abstract: A method of determining one or more color characteristics of a colored microsphere comprising: providing a microarray of microspheres, at least one of which has a color characteristic; capturing the microarray with an electronic color image sensor assembly having a matrix of pixels to produce an electronic microarray image; detecting the location of a microsphere within the captured microarray image; and identifying a color characteristic of the detected microsphere.
    Type: Application
    Filed: June 26, 2003
    Publication date: December 30, 2004
    Inventors: Samuel Chen, Krishnan Chari, Martin C. Kaplan, Douglas L. Vizard, Joaquin Calcines
  • Publication number: 20030175719
    Abstract: A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of nucleic acid probe modified micro-spheres immobilized in a coating containing a gelling agent or a precursor to a gelling agent, wherein a first portion of the micro-spheres is submerged in the gelatin coating and a second portion is exposed above the gelatin coating and is substantially free of gelatin, at least one sub-population of the population micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a nucleic acid probe sequence; contacting the array with a target nucleic acid sequence; and detecting the color barcode of the sub-population of micro-spheres due to the interaction of the probe nucleic acid sequence and the fluorescently/chemiluminescently labeled nucleic acid sample target nucleic acid sequence.
    Type: Application
    Filed: March 15, 2002
    Publication date: September 18, 2003
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Publication number: 20030143542
    Abstract: A method of identifying nucleic acid samples comprising:
    Type: Application
    Filed: December 21, 2001
    Publication date: July 31, 2003
    Inventors: Tiecheng A. Qiao, Krishnan Chari, Douglas L. Vizard
  • Publication number: 20030068609
    Abstract: A coating composition for making a microarray comprising: a gelling agent or a precursor to a gelling agent and microspheres dispersed in a fluid; wherein, upon coating the composition on a substrate, said microspheres become immobilized in the plane of coating and form a random pattern on the substrate. The substrate is characterized by an absence of specific sites capable of interacting physically or chemically with the microspheres.
    Type: Application
    Filed: August 29, 2001
    Publication date: April 10, 2003
    Inventors: Krishan Chari, Tiecheng A. Qiao, Douglas L. Vizard
  • Patent number: 6444988
    Abstract: An electronic imaging system including; a transparent support having first and second sides; an optical interference coating on the first side of the transparent support; and a first prompt phosphor layer overlaying the interference coating for use in high resolution ionizing radiation imaging application or in low energy ionizing radiation imaging applications. The system also includes a second prompt phosphor layer which is removably overlaid on the first prompt phosphor layer for use in high energy ionizing radiation applications; and an electronic camera for converting the light image produced by the first and the second prompt phosphor layers when exposed to an ionizing radiation image, into an electronic image; wherein the phosphor of the first and second prompt phosphor layers emits radiation at wavelengths which are passed by the optical interference coating.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: September 3, 2002
    Assignee: Eastman Kodak Company
    Inventor: Douglas L. Vizard
  • Patent number: 6346707
    Abstract: An imaging system with an imaging assemblage including a prompt phosphor layer for converting an ionizing radiation image into a light image, and a transparent layer supporting the phosphor layer; wherein the light image is transmitted through the transparent layer; an electronic camera for converting the light image into an electronic image; and a light image transmission system between the imaging assemblage and the electronic camera for transmitting the light image to the electronic camera.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: February 12, 2002
    Assignee: Eastman Kodak Company
    Inventors: Douglas L. Vizard, Joel N. Helfer, William E. McLaughlin, David J. Steklenski
  • Patent number: 6143459
    Abstract: A photosensitive film assembly comprising;a polymeric support having first and second side, said support being reflective to non penetrating radiation; anda photosensitive layer on at least one of said first and second sides of said support.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: November 7, 2000
    Assignee: Eastman Kodak Company
    Inventor: Douglas L. Vizard
  • Patent number: 5945292
    Abstract: This invention discloses a gene for the identification of cells comprising a secretion leader segment, a cell marker segment and a transmembrane segment. The gene can be used to identify cells transfected with the gene by the steps of: inserting the gene having a secretion leader segment, a cell marker segment and a transmembrane segment into the DNA or RNA of a cell, allowing the cell to express the gene, and detecting the expressed cell marker segment of the gene.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: August 31, 1999
    Assignee: Sigma-Aldrich Co.
    Inventors: Billy L. Brizzard, Darlene W. Bianca, Richard G. Chubet, Douglas L. Vizard, Thomas Patrick Hopp
  • Patent number: 5830629
    Abstract: An assemblage useful for autoradiography comprising, in order, a sample layer containing a radioactively labeled biological sample in contact with a phosphor layer, a film layer and a reflector layer. The phosphor layer is preferably a gadolinium oxysulfide containing layer and the film is preferably a photographic film containing a tabular grain emulsion.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: November 3, 1998
    Assignee: Eastman Kodak Company
    Inventors: Douglas L. Vizard, David J. Steklenski
  • Patent number: 5779869
    Abstract: An electrophoresis device consists of a housing which has opening(s) for the movement of gases from inside the housing to outside the housing and opening(s) for the movement of gases from outside the housing to inside the housing, whereby the condensation of gases on the inside of the housing is avoided or minimized.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: July 14, 1998
    Assignee: Eastman Kodak Company
    Inventors: Joel Norman Helfer, Douglas L. Vizard
  • Patent number: 5731425
    Abstract: This invention discloses a gene for the identification of cells comprising a selection leader segment, a cell marker segment and a transmembrane segment. The gene can be used to identify cells transfected with the gene by the steps of: inserting the gene having a selection leader segment, a cell marker segment and a transmembrane segment into the DNA or RNA of a cell, allowing the cell to express the gene, and detecting the expressed cell marker segment of the gene.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: March 24, 1998
    Assignee: Eastman Kodak Company
    Inventors: Billy L. Brizzard, Darlene W. Bianca, Richard G. Chubet, Douglas L. Vizard, Thomas Patrick Hopp