Abstract: A system for selecting a sensitivity level for adjusting an intensity setting for therapy provided to a patient includes one or more processors and one or more processors coupled to the memory. The one or more processors are configured to receive an indication of an input to adjust an intensity setting related to the therapy provided to the patient and determine a sensitivity level for adjustment of the intensity setting based on an efficacy of the therapy provided to the patient. The one or more processors are further configured to determine an updated intensity level for the intensity setting based on the sensitivity level and the input to adjust the intensity setting and output an instruction to cause a medical device to provide the therapy at the updated intensity level.

Abstract: Systems and methods are disclosed for a configurable interconnect address remapper with event detection. For example, an integrated circuit can include a processor core configured to execute instructions. The processor core includes region registers defined by a From Address range and a To Address, a register storing a number of regions defined in the integrated circuit, interrupt enable registers associated with each pair of region registers, and event flags associated with each pair of region registers; an interconnection system handling transactions from the processor core; an interconnect address remapper translating an address associated with a transaction using the one or more pair of region registers; and an interrupt controller receiving an interrupt signal from the interconnect address remapper when the interrupt enable registers are enabled and at least one raised event flags when at least one of the one or more pair of region registers matches the transaction address.

Abstract: A system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to perform steps of a method. The system may provide an augmented environment that facilitates a transaction. The system may store profile data including user payment or user profile information. The system may then receive environmental data, and identify one or more action items in the environmental data. In response to this identification, the system may augment the environmental data by adding virtual environmental data, and then provide this virtual environmental data to a device to create an augmented environment. The system can then receive user input data, and provide purchase request data to a merchant terminal in response to those inputs.

Abstract: A system includes one or more memory devices storing instructions, and one or more processors configured to execute the instructions to perform steps of a method for providing an interactive virtual environment. The system may receive environmental data, and augment the environmental data by adding virtual environmental data. The system may then provide this virtual environment to two or more devices. The system can then receive user input, and modify the virtual environment in response to those inputs.

Abstract: A tube coupling for coupling a first tube and a second tube. The tube coupling includes an inner shroud including a ball portion and an outer shroud including a socket portion. The socket portion receives the ball portion. The tube coupling includes a compressive ring configured to elastically compress the outer shroud onto the inner shroud. The ball portion and the socket portion form a ball and socket joint. The ball and socket joint allows relative angular movement and relative axial movement between the inner shroud and the outer shroud.

Abstract: A tube assembly includes a first tube, a second tube, and a tube coupling. The tube coupling is for coupling the first tube to the second tube. The tube coupling may include protrusions, indentations, compressive rings, compressive bands, and/or connection members. The protrusions and/or indentions may be located on the first tube, the second tube, the compressive band, and/or the connection member. The compressive ring and/or compressive band is placed on an outer surface of the first tube and/or the second tube. The compressive ring provides an elastic compressive force to the first tube and/or the second tube such that the protrusion is secured within the indentation. The tube coupling provides a weld-free connection between the first tube and the second tube.

Abstract: A tube coupling for coupling a first tube and a second tube. The tube coupling includes an inner shroud including a ball portion and an outer shroud including a socket portion. The socket portion receives the ball portion. The tube coupling includes a compressive ring configured to elastically compress the outer shroud onto the inner shroud. The ball portion and the socket portion form a ball and socket joint. The ball and socket joint allows relative angular movement and relative axial movement between the inner shroud and the outer shroud.

Abstract: A gas turbine engine including a wall assembly, a seal assembly, and a member extended through the wall assembly is provided. The wall assembly defines an opening through which the member is extended, and the wall assembly defines a first side and a second side opposite of the first side along a direction of extension of the member through the wall assembly. The seal assembly includes a retaining portion extended at least partially co-directional to the member. The retaining portion is configured to couple around the member and extend through the opening. The seal assembly further includes a locking portion configured to sealingly attach to the wall assembly and the retaining portion at an interface between the locking portion and the retaining portion.

Abstract: In one exemplary embodiment of the present disclosure a fluid coupling assembly defining an axial direction, a radial direction, and a circumferential direction is provided.

Abstract: A seal assembly for a propulsion system couples a plurality of manifolds of a manifold assembly of the propulsion system generally in fluid communication. Each of the manifolds defines a first end and a second end. The seal assembly includes a coupling member attaching the first end and the second end of the manifold assembly together in fluid communication; one or more seals disposed between the coupling member and at least one of the first end and the second end of the manifold; and a retainer adjacent to the coupling member and the seal. The retainer defines a radial wall and an axial wall, in which the radial wall is extended generally from one or more of the first end and the second end of the manifold alongside the coupling member and the seal, and the axial wall is extended generally from the radial wall alongside the coupling member and the seal.

Abstract: A gas turbine engine including a wall assembly, a seal assembly, and a member extended through the wall assembly is provided. The wall assembly defines an opening through which the member is extended, and the wall assembly defines a first side and a second side opposite of the first side along a direction of extension of the member through the wall assembly. The seal assembly includes a retaining portion extended at least partially co-directional to the member. The retaining portion is configured to couple around the member and extend through the opening. The seal assembly further includes a locking portion configured to sealingly attach to the wall assembly and the retaining portion at an interface between the locking portion and the retaining portion.

Abstract: In one exemplary embodiment of the present disclosure a fluid coupling assembly defining an axial direction, a radial direction, and a circumferential direction is provided.

Abstract: The present disclosure is directed to a seal assembly for a propulsion system. The seal assembly couples a plurality of manifolds of a manifold assembly of the propulsion system generally in fluid communication. Each of the manifolds defines a first end and a second end. The seal assembly includes a coupling member attaching the first end and the second end of the manifold assembly together in fluid communication; one or more seals disposed between the coupling member and at least one of the first end and the second end of the manifold; and a retainer adjacent to the coupling member and the seal. The retainer defines a radial wall and an axial wall, in which the radial wall is extended generally from one or more of the first end and the second end of the manifold alongside the coupling member and the seal, and the axial wall is extended generally from the radial wall alongside the coupling member and the seal.

Abstract: A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage exposed sample, and a substance which enhances bacteriophage amplification or sensitivity; providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to infect the microorganism; and assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism.

Abstract: A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: (a) combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage-exposed sample; (b) providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to attach to the target microorganism while inhibiting phage replication in a potentially cross-reactive, non-target microorganism; and (c) assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism; wherein the amount of the bacteriophage is between 10% to 70% of the threshold number of bacteriophage that the assay can detect, or between 1×106 pfu/mL and 7×106 pfu/mL.

Abstract: The present invention provides novel methods and reagents for detecting the binding of protein targets to nucleic acid ligands. Using Universal Protein Stains (UPS), proteins bound by nucleic acid ligands may be labeled with a detectable moiety. The methods and reagents are particularly useful for the detection of protein targets bound to multiplexed arrays of nucleic acid ligands. The present invention also provides novel methods for the multiplexed evaluation of photocrosslinking nucleic acid ligands. The methods allow one simultaneously to: (1) evaluate the performance (dynamic range) of a plurality of photocrosslinking nucleic acid ligands; and (2) assess the specificity of each photocrosslinking nucleic acid ligand for its cognate target protein. Photocrosslinking nucleic acid ligands with the most desirable properties can then be selected for use in diagnostic and prognostic medical assays.

Abstract: A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage exposed sample, and a substance which enhances bacteriophage amplification or sensitivity; providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to infect the microorganism; and assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism.

Abstract: An apparatus, system and method is provided facilitating the planning and tracking of nutrient consumption and expenditure by humans, especially children, including various indicators such as graphical images pertaining to potential dietary intake of foods and liquids like vegetables, fruits and water and physical activities like running, dancing and the like, wherein the various indicators are uniquely charted to accomplish the monitoring and/or projecting of nutrient utilization.

Abstract: Apparatus comprising a signal tube extending from an engine component on a hot side of a firewall in a gas turbine engine to an engine control mechanism disposed on a cool side of the firewall. The apparatus includes a fuse in the portion of the signal tube extending through the hot side. An exemplary fuse includes a temperature-sensitive inner member that is deformable upon exposure to temperatures greater than a predetermined temperature. The fuse is operative responsive to a breach in the signal tube to change from a first condition to a second condition to prevent an over-temperature situation on the cool side of the firewall. An outer member substantially enclosing the inner member provides information about the condition of the fuse. A system utilizing the fuse includes a gas turbine engine having a firewall separating a hot side from a cool side, an engine control mechanism disposed on the cool side, and a signal tube extending from a component on the hot side to the engine control mechanism.

Abstract: A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: (a) combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage-exposed sample; (b) providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to attach to the target microorganism while inhibiting phage replication in a potentially cross-reactive, non-target microorganism; and (c) assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism; wherein the amount of the bacteriophage is between 10% to 70% of the threshold number of bacteriophage that the assay can detect, or between 1×106pfu/mL and 7×106pfu/mL.