Abstract: A pouch package system is fabricated from a compliant plastic film tube that includes a series of separate compartments formed by a plurality of transverse seals spaced along the tube. Contiguous pairs of compartments are mutually separated by means of the seals and are hermetically sealable for storing reactive materials under anaerobic conditions. A flexible narrow flattened conduit communicates each contiguous pair of compartments across the separating seal and comprises an unsealed portion in a common plane wherein the facing surfaces of the tube are joined. During storing of the materials the compartments are isolated by closing the conduit with a kink thereacross formed by a fold in the separating seal. Flattening the fold removes the kink to open the conduit. The separated materials are then combined and mixed by kneading the tube.