Abstract: A multi-actuated micro-pipette controller is actuated in at least three different ways. First, the multi-actuated micro-pipette controller may be employed similar to a striper for denudation of cumulus cells and transfer of oocytes and embryos by depressing an actuator assembly operably coupled to a ballonet. Second, the multi-actuated micro-pipette controller may be actuated similar to a SWEMED™ denudation pipette by pressing directly on the ballonet while it is seated in a primary housing and a secondary housing, without employing an actuator assembly of the primary housing. Third, the multi-actuated micro-pipette controller may be actuated by removing the ballonet and employing it similar to a PASTEUR™ pipette.