Patents by Inventor Durvanei Augusto Maria

Durvanei Augusto Maria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF
    Publication number: 20230130823
    Abstract: The present invention reports the obtaining of carbonyl compounds and derivatives, through syntheses with high yield and purity, providing anti-humoral active principles with selective antiproliferative properties and anti-metastatic activity. The present invention refers to the development of new polyfunctional push-pull butadienes and their O and C-prenylated, benzoylated and iodide derivatives, with high electronic conjugation in the lateral chain. These compounds exhibit high anti-tumor selectivity, causing cell death by apoptosis, also show anti-metastatic and non-mutagenic properties in the experimental studies performed.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 27, 2023
    Applicants: ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A, FUNDAÇÃO UNIVERSIDADE FEDERAL DO ABC, INSTITUTO BUTANTAN
    Inventors: Anderson ORZARI RIBEIRO, Carolina PASSARELLI GONÇALVES, Durvanei AUGUSTO MARIA, José Agustín QUINCOCES SUÁREZ, Manuel SALUSTIANO ALMEIDA SAAVEDRA
  • Method for producing embryonic-like stem cells from ticks (acari: ixodidae), composition, uses thereof and diagnostic methods
    Patent number: 10869915
    Abstract: The invention refers to a process for the production of a continuous cell line of simile embryo stem cells, such as Amblyomma sculptum (Acari: Ixodidae), known as line IBU/ASE-16 (access number with CNCM: 1-5000) and its uses. More specifically, the invention refers to a process for the production of the line IBU/ASE-16 and their use for obtaining extracts for the production of vaccines and candidate recombinant proteins for biopharmaceuticals and acaricides, production of diagnostic kits for the detection of antigens and/or antibodies for animal and human use, obtaining clones for use in genotyping and use as a substrate for the isolation and culture of pathogens.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: December 22, 2020
    Assignees: BIOTICK PESQUISA E DESENVOLVIMIENTO TECNOLÓGICO LTDA, FUNDACÃO BUTANTAN
    Inventors: Darci Moraes Barros Battesti, Irina Kerkis, Ronaldo Zucatelli Mendonca, Durvanei Augusto Maria, Angelina Cirelli Moraes
  • METHOD FOR PRODUCING EMBRYONIC-LIKE STEM CELLS FROM TICKS (ACARI: IXODIDAE), COMPOSITION, USES THEREOF AND DIAGNOSTIC METHODS
    Publication number: 20180236051
    Abstract: The invention refers to a process for the production of a continuous cell line of simile embryo stem cells, such as Amblyomma sculptum (Acari: Ixodidae), known as line IBU/ASE-16 (access number with CNCM: 1-5000) and its uses. More specifically, the invention refers to a process for the production of the line IBU/ASE-16 and their use for obtaining extracts for the production of vaccines and candidate recombinant proteins for biopharmaceuticals and acaricides, production of diagnostic kits for the detection of antigens and/or antibodies for animal and human use, obtaining clones for use in genotyping and use as a substrate for the isolation and culture of pathogens.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 23, 2018
    Inventors: Darci Moraes Barros Battesti, Irina Kerkis, Ronaldo Zucatelli Mendonca, Durvanei Augusto Maria, Angelina Cirelli Moraes
  • Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals
    Patent number: 9381169
    Abstract: The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs. The present invention further relates to the use of said polyfunctional metal phenolates in the preparation of drugs for the treatment, prophylaxis or prevention of neoplasic diseases in humans and animals.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: July 5, 2016
    Assignees: UNIVERSIDADE BANDEIRANTE DE SÃO PAULO—ACADEMIA PAULISTA ANCHIETA S/C LT, FUNDAÇ ÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO—FAPESP
    Inventors: José Agustin Quincoces Suárez, Durvanei Augusto Maria, Paulo Celso Pardi, Fernanda Faião Flores, Reginaldo Pereira Santos, Daniela Gonçales Rando
  • Methods to prepare penta-1,4-dien-3-ones and substituted cyclohexanones and derivatives with antitumoral and antiparasitic properties, the compounds and their uses
    Patent number: 8859625
    Abstract: The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition including the referred compounds, method of treatment for cancer and parasitic diseases.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: October 14, 2014
    Assignee: Universidade Bandeirante de Sao Paulo-Academia, Paulista Anchieta S/C Ltda
    Inventors: José Agustin Quincoces Suárez, Durvanei Augusto Maria, Daniela Goncales Rando, Clizete Aparecida Sbravate Martins, Paulo Celso Pardi, Pamela Oliveira De Souza
  • Methods for growing tissue with Lopap-based pharmaceutical compositions
    Patent number: 8673840
    Abstract: The invention refers to pharmaceutical compositions and cosmetic compositions comprising a prophylactic or therapeutically effective quantity of at least one polypeptide substantially identical to Lopap (a lipocalin-related protein with prothrombin activating protease activity). The invention refers to the use of these compositions as modulators of cell death and anti-aging agents.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: March 18, 2014
    Assignees: Biolabs Sanus Farmaceutica Ltda., Fundacao de Amparao a Pesquisa do Estado de Sao Paulo-Fapesp
    Inventors: Ana Marisa Chudzinski-Tavassi, Marcio Falci, Cleyson Valenca Reis, Durvanei Augusto Maria
  • Kunitz-type recombinant inhibitor
    Patent number: 8440795
    Abstract: The present invention presents a Kunitz-type recombinant inhibitor obtained from a gene cloned from a cDNA library of salivary glands of the Amblyomma cajennense, and the inhibitor named Amblyomin-X has molecular mass of 13,500 Da.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: May 14, 2013
    Assignee: Coinfair-Consórcio De Indústrias Farmacêuticas
    Inventors: Durvanei Augusto Maria, Ana Marisa Chudzinski-Tavassi, Isabel De Fatima Correia Batista, Paulo Lee Ho
  • PHARMACEUTICAL COMPOSITION AND USE OF THE PHARMACEUTICAL COMPOSITION FOR THE TREATMENT, PROPHYLAXIS OR PREVENTION OF NEOPLASTIC DISEASES IN HUMANS AND ANIMALS
    Publication number: 20120082703
    Abstract: The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs. The present invention further relates to the use of said polyfunctional metal phenolates in the preparation of drugs for the treatment, prophylaxis or prevention of neoplasic diseases in humans and animals.
    Type: Application
    Filed: November 11, 2009
    Publication date: April 5, 2012
    Applicant: UNIVERSIDADE BANDEIRANTE DE SAO PAULO-ACADEMIA PAULISTA ANCHETA S/C LTDA
    Inventors: José Agustín Quincoces Suárez, Durvanei Augusto Maria, Paulo Celso Pardi, Fernanda Faião Flores, Reginaldo Pereira Santos, Daniela Gonçales Rando
  • METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES
    Publication number: 20100029763
    Abstract: The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition including the referred compounds, method of treatment for cancer and parasitic diseases.
    Type: Application
    Filed: July 6, 2007
    Publication date: February 4, 2010
    Inventors: Jose Agustin Quincoces Suarez, Durvanei Augusto Maria, Daniela Goncales Rando, Clizete Aparecida Sbravaate Martins, Paulo Celso Pardi, Pamela Oliveira De Souza
  • Kunitz-type recombinant inhibitor
    Publication number: 20090042786
    Abstract: The present invention presents a Kunitz-type recombinant inhibitor obtained from a gene cloned from a cDNA library of salivary glands of the Amblyomma cajennense, and the inhibitor named Amblyomin-X has molecular mass of 13,500 Da.
    Type: Application
    Filed: March 14, 2007
    Publication date: February 12, 2009
    Inventors: Durvanei Augusto Maria, Ana Marisa Chudzinski-Tavassi, Isabel De Fatima Correia Batista, Paulo Lee Ho