Patents by Inventor Dwo Lynm

Dwo Lynm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions and methods for use
    Patent number: 6852721
    Abstract: The present invention relates to diazabicyclic compounds, preferably to N-aryl diazabicyclic compounds. Of particular interest are 2-pyridinyl diazabicyclic compounds, such as (1S,4S)-2-(5-(3-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. Other exemplary compounds of the present invention include (1S,4S)-2-(5-(4-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-(3-thienyl)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-(4-fluorophenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, and (1S,4S)-2-(5-benzoyl-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. The present invention also relates to prodrug derivatives of the compounds of the present invention.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: February 8, 2005
    Assignee: Targacept, Inc.
    Inventors: Craig Harrison Miller, Gary Maurice Dull, Lan Miao, Dwo Lynm, Jeffrey Daniel Schmitt, Thomas Jeffrey Clark
  • Pharmaceutical compositions and methods for use
    Publication number: 20030087915
    Abstract: Pharmaceutical compositions incorporate aryl substituted olefinic amine compounds. Representative compounds are (2S)-(4E)-N-methyl-5-[3-(5-isopropoxy-1-oxopyridin)yl)]-4-penten-2-amine, (4E)-N-methyl-5-(3-(1-oxopyridin)yl)4-penten-2-amine, (4E)-N-methyl-5-(3-(5-((carboxymethyl)oxy)pyridin)yl)-4-penten-2-amine and (4E)-N-methyl-5-(3-(1-oxopyridin)yl)-4-penten-2-amine.
    Type: Application
    Filed: September 16, 2002
    Publication date: May 8, 2003
    Inventors: Gary Maurice Dull, Craig Harrison Miller, William Scott Caldwell, Dwo Lynm, Balwinder Singh Bhatti, Jeffrey Daniel Schmitt, Gary Dwight Byrd
  • Oxopyridinyl pharmaceutical compositions and methods for use
    Patent number: 6455554
    Abstract: Pharmaceutical compositions incorporate aryl substituted olefinic amine compounds. Representative compounds are (2S)-(4E)-N-methyl-5-[3-(5-isopropoxy-1-oxopyridin)yl)]-4-penten-2-amine, (4E)-N-methyl-5-(3-(1-oxopyridin)yl)-4-penten-2-amine, (4E)-N-methyl-5-(3-(5-((carboxymethyl)oxy)pyridin)yl)-4-penten-2-amine and (4E)-N-methyl-5-(3-(1-oxopyridin)yl)-4-penten-2-amine.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: September 24, 2002
    Assignee: Targacept, Inc.
    Inventors: Gary Maurice Dull, Craig Harrison Miller, William Scott Caldwell, Dwo Lynm, Balwinder Singh Bhatti, Jeffrey Daniel Schmitt, Gary Dwight Byrd
  • Pharmaceutical compositions and methods for use
    Patent number: 6440970
    Abstract: The present invention relates to diazabicyclic compounds, and preferably N-aryl diazabicyclic compounds. Of particular interest are 2-pyridyl diazabicyclic compounds, such as (1S,4S)-2-(3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. Other exemplary compounds of the present invention include: (1S,4S)-2-(5-(4-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-pyrimidinyl)-2,5-diazabicyclo[2.2.1]heptane and (1S,4S)-2-(6-chloro-3-pyridazinyl)-2,5-diazabicyclo[2.2.1]heptane. The present invention also relates to prodrug derivatives of the compounds of the present invention.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: August 27, 2002
    Assignee: Targacept, Inc.
    Inventors: Thomas Jeffrey Clark, Gary Maurice Dull, Dwo Lynm, Lan Miao, Craig Harrison Miller, Jeffrey Daniel Schmitt
  • Pharmaceutical compositions and methods for use
    Publication number: 20020013309
    Abstract: The present invention relates to diazabicyclic compounds, preferably to N-aryl diazabicyclic compounds. Of particular interest are 2-pyridyl diazabicyclic compounds, such as (1S,4S)-2-(5-(3-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. Other exemplary compounds of the present invention include: (1S,4S)-2-(5-(4-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1 ]heptane, (1S,4S)-2-(5-(3,4-dimethoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-(4-fluorophenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1 ]heptane, and (1S,4S)-2-(5-benzoyl-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. The present invention also relates to prodrug derivatives of the compounds of the present invention.
    Type: Application
    Filed: May 24, 2001
    Publication date: January 31, 2002
    Inventors: Craig Harrison Miller, Gary Maurice Dull, Lan Miao, Dwo Lynm, Jeffrey Daniel Schmitt, Thomas Jeffrey Clark
  • Tobacco treatment process
    Patent number: 5370139
    Abstract: A process is provided for treating tobacco material for use in a smoking article comprising the step of applying a flavorful and aromatic casing and top dressing composition comprising a weak ammonium salt and a sugar or sugar derivative to a tobacco material. The present also provides a smoking article including tobacco material wherein the tobacco material is in intimate contact with a casing and top casing composition comprising a weak ammonium salt and a sugar or sugar derivative.
    Type: Grant
    Filed: October 14, 1993
    Date of Patent: December 6, 1994
    Assignee: R. J. Reynolds Tobacco Company
    Inventors: Chi-Kuen Shu, Brian M. Lawrence, Joyce R. Durham, Dwo Lynm
  • Cigarette
    Patent number: 4715389
    Abstract: A cigarette having internal heat sinks of aluminum mesh and a section of carbonized flue-cured tobacco stem material containing adsorbed nicotine produces smoke having lower TPM and higher nicotine than smoke from conventional cigarettes.
    Type: Grant
    Filed: September 15, 1986
    Date of Patent: December 29, 1987
    Assignee: R. J. Reynolds Tobacco Company
    Inventors: Dwo Lynm, Carl C. Morrison, Ronald W. Hutcherson, Sr.
  • Pharmaceutical compositions and methods for use
    Patent number: RE41439
    Abstract: The present invention relates to diazabicyclic compounds, preferably to N-aryl diazabicyclic compounds. Of particular interest are 2-pyridinyl diazabicyclic compounds, such as (1S,4S)-2-(5-(3-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. Other exemplary compounds of the present invention include (1S,4S)-2-(5-(4-methoxyphenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-(3-thienyl)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, (1S,4S)-2-(5-(4-fluorophenoxy)-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane, and (1S,4S)-2-(5-benzoyl-3-pyridyl)-2,5-diazabicyclo[2.2.1]heptane. The present invention also relates to prodrug derivatives of the compounds of the present invention.
    Type: Grant
    Filed: February 5, 2007
    Date of Patent: July 13, 2010
    Assignee: Targacept, Inc.
    Inventors: Craig Harrison Miller, Gary Maurice Dull, Lan Miao, Dwo Lynm, Jeffrey Daniel Schmitt, Thomas Jeff Clark