Patents by Inventor E. Douglas Grindstaff, II

E. Douglas Grindstaff, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10383837
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: August 20, 2019
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20190224152
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: August 14, 2018
    Publication date: July 25, 2019
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 10076507
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: September 18, 2018
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 9901573
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: February 27, 2018
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Patent number: 9855235
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: January 2, 2018
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20170368045
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Application
    Filed: June 9, 2017
    Publication date: December 28, 2017
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Publication number: 20170312240
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: May 15, 2017
    Publication date: November 2, 2017
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 9713609
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: July 25, 2017
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Patent number: 9682053
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: June 20, 2017
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20170000777
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Application
    Filed: July 8, 2016
    Publication date: January 5, 2017
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Publication number: 20160338983
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: May 25, 2016
    Publication date: November 24, 2016
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 9408410
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 9, 2016
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael B. Zemel, E. Douglas Grindstaff, II
  • Patent number: 9351967
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: May 31, 2016
    Assignee: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20160113317
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Application
    Filed: October 29, 2015
    Publication date: April 28, 2016
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Publication number: 20160113915
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: October 29, 2015
    Publication date: April 28, 2016
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20150342914
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: June 22, 2015
    Publication date: December 3, 2015
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 9198454
    Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: December 1, 2015
    Assignee: NUSIRT SCIENCES, INC.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II
  • Patent number: 9198883
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: December 1, 2015
    Assignee: NUSIRT SCIENCES, INC.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Patent number: 9072692
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: July 7, 2015
    Assignee: NUSIRT SCIENCES, INC.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
  • Publication number: 20140148488
    Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.
    Type: Application
    Filed: April 19, 2013
    Publication date: May 29, 2014
    Applicant: NuSirt Sciences, Inc.
    Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer