Patents by Inventor E. Douglas Grindstaff, II
E. Douglas Grindstaff, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10383837Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: August 14, 2018Date of Patent: August 20, 2019Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20190224152Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: August 14, 2018Publication date: July 25, 2019Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 10076507Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: November 17, 2017Date of Patent: September 18, 2018Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 9901573Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: GrantFiled: June 9, 2017Date of Patent: February 27, 2018Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Patent number: 9855235Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: May 15, 2017Date of Patent: January 2, 2018Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20170368045Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: ApplicationFiled: June 9, 2017Publication date: December 28, 2017Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Publication number: 20170312240Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: May 15, 2017Publication date: November 2, 2017Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 9713609Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: GrantFiled: July 8, 2016Date of Patent: July 25, 2017Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Patent number: 9682053Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: May 25, 2016Date of Patent: June 20, 2017Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20170000777Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: ApplicationFiled: July 8, 2016Publication date: January 5, 2017Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Publication number: 20160338983Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: May 25, 2016Publication date: November 24, 2016Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 9408410Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: GrantFiled: October 29, 2015Date of Patent: August 9, 2016Assignee: NuSirt Sciences, Inc.Inventors: Michael B. Zemel, E. Douglas Grindstaff, II
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Patent number: 9351967Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: October 29, 2015Date of Patent: May 31, 2016Assignee: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20160113317Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: ApplicationFiled: October 29, 2015Publication date: April 28, 2016Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Publication number: 20160113915Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: October 29, 2015Publication date: April 28, 2016Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20150342914Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: June 22, 2015Publication date: December 3, 2015Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 9198454Abstract: The present invention provides for compositions, methods and kits for regulating energy metabolism. In one aspect, the invention provides for compositions that comprise a combination of (a) branched chain amino acids, such as leucine, and (b) vitamin B6, or any precursors or metabolites of (a) or (b). These combinations may be synergistic and/or effective for reducing weight or adipose volume. In another aspect, the invention provides for methods of regulating energy metabolism by the administration of one or more compositions comprising branched chain amino acids and vitamin B6. The invention also provides for kits comprising compositions of branched chain amino acids and vitamin B6 packaged in an oral dose form with usage instructions.Type: GrantFiled: October 26, 2012Date of Patent: December 1, 2015Assignee: NUSIRT SCIENCES, INC.Inventors: Michael Zemel, E. Douglas Grindstaff, II
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Patent number: 9198883Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: June 22, 2015Date of Patent: December 1, 2015Assignee: NUSIRT SCIENCES, INC.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Patent number: 9072692Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: GrantFiled: April 19, 2013Date of Patent: July 7, 2015Assignee: NUSIRT SCIENCES, INC.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer
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Publication number: 20140148488Abstract: Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.Type: ApplicationFiled: April 19, 2013Publication date: May 29, 2014Applicant: NuSirt Sciences, Inc.Inventors: Michael Zemel, E. Douglas Grindstaff, II, Antje Bruckbauer