Patents by Inventor E. Lerner
E. Lerner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240139025Abstract: Caps and other luer taper medical devices having a volume displacing protrusion are described. The volume displacing protrusion can extend in an axial direction away from an end wall inside the female hub and be configured to create a seal that can be substantially airtight with a distal end of a syringe that is engaged with the cap or other luer taper medical device. The volume displacing protrusion of the cap or other luer taper medical device can create a seal with a distal end of a syringe before an outside surface of the syringe tip creates a seal with the luer taper of the female hub.Type: ApplicationFiled: January 9, 2024Publication date: May 2, 2024Inventor: Leonid E. Lerner
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Patent number: 11865039Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.Type: GrantFiled: November 23, 2022Date of Patent: January 9, 2024Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20230226280Abstract: An injection device includes one or more of a barrel having an open proximal end, an open distal end, and a sidewall therebetween; a plunger; and a conduit or connector. The barrel may be configured to house a volume of therapeutic agent. The plunger may have a proximal end, a distal end, and an elongate body. The conduit or connector may be operably attached to the open distal end of the barrel. The distal end of the barrel can include a variable inner diameter segment configured such that movement of the plunger to the variable inner diameter segment of the distal end of the barrel creates an audible and/or tactile feedback sensation to a user.Type: ApplicationFiled: September 24, 2021Publication date: July 20, 2023Inventor: Leonid E. Lerner
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Publication number: 20230078528Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: November 23, 2022Publication date: March 16, 2023Inventor: Leonid E. Lerner
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Patent number: 11554041Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.Type: GrantFiled: March 9, 2018Date of Patent: January 17, 2023Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20220376127Abstract: A photovoltaic cell includes a semiconductor element (20) formed from a direct semiconductor and a transparent biasing agent (28) overlying a first portion of the front face (22) of the semiconductor, the biasing agent producing a first depletion region (30) in the semiconductor element. A collector (40) directly contacts a second portion of the front face. The collector produces a second depletion region (44) in the semiconductor element. The collector (40) is out of direct conductive contact with the biasing agent (28) but in proximity to the biasing agent. A continuous region at least partially depleted of majority carriers extends between the first and second depletion regions at the front face of the semiconductor element, The continuous region may include overlapping portions of the first and second depletion regions (30,44), or may include an additional depletion region (160) formed by a charged dielectric (147).Type: ApplicationFiled: July 13, 2020Publication date: November 24, 2022Applicant: Columbus Photovoltaics LLCInventors: Ian Ferguson, Corey E. Lerner, Chuanle Zhou
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Publication number: 20220015945Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: February 1, 2021Publication date: January 20, 2022Inventor: Leonid E. Lerner
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Patent number: 10905587Abstract: Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.Type: GrantFiled: August 5, 2016Date of Patent: February 2, 2021Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20200214889Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: January 6, 2020Publication date: July 9, 2020Inventor: Leonid E. Lerner
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Patent number: 10525009Abstract: The present invention provides improved formulations of 6-mercaptopurine that exhibit better bioavailability and faster dissolution than previous formulations.Type: GrantFiled: June 17, 2016Date of Patent: January 7, 2020Assignee: Hadasit Medical Research Services and Development Ltd.Inventors: Itzhak E. Lerner, Moshe Flashner-Barak, Erwin v Achthoven, Hans Keegstra, Ruud Smit
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Patent number: 10524957Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: GrantFiled: August 18, 2016Date of Patent: January 7, 2020Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20200000635Abstract: Injection devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: April 8, 2019Publication date: January 2, 2020Inventor: Leonid E. Lerner
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Patent number: 10478335Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: GrantFiled: August 7, 2018Date of Patent: November 19, 2019Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20190312167Abstract: A photovoltaic cell incorporating a semiconductor element (10) composed entirely of a single conductivity type. A biasing agent (26) having a work function different from that of the semiconductor element overlies a face of the element and produces a band bending and thus an electric field in a space charge region. Electrodes are in contact with the semiconductor element within the space charge region. Carriers generated by light absorbed in the semiconductor element are accelerated toward the electrodes by the field.Type: ApplicationFiled: June 10, 2019Publication date: October 10, 2019Applicant: Columbus Photovoltaics LLCInventor: Corey E. Lerner
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Patent number: 10355157Abstract: A photovoltaic cell incorporating a semiconductor element (10) composed entirely of a single conductivity type. A biasing agent (26) having a work function different from that of the semiconductor element overlies a face of the element and produces a band bending and thus an electric field in a space charge region. Electrodes are in contact with the semiconductor element within the space charge region. Carriers generated by light absorbed in the semiconductor element are accelerated toward the electrodes by the field.Type: GrantFiled: November 3, 2014Date of Patent: July 16, 2019Assignee: Columbus Photovoltaics LLCInventor: Corey E. Lerner
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Patent number: 10251779Abstract: Injection devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described.Type: GrantFiled: April 25, 2016Date of Patent: April 9, 2019Assignee: OcuJect, LLCInventor: Leonid E. Lerner
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Publication number: 20180360656Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: March 9, 2018Publication date: December 20, 2018Inventor: Leonid E. Lerner
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Publication number: 20180344523Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: August 7, 2018Publication date: December 6, 2018Inventor: Leonid E. Lerner
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Publication number: 20180333300Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: April 12, 2018Publication date: November 22, 2018Inventor: Leonid E. Lerner
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Publication number: 20180263816Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.Type: ApplicationFiled: May 21, 2018Publication date: September 20, 2018Inventor: Leonid E. Lerner