Abstract: The present invention is a biopsy specimen collection device having chambers, for receiving tissue samples of differing sizes from various locations within a particular anatomical organ or system, consolidated on a base or tray. The site-specific chambers of the collection device are mounted over a schematic diagram of the anatomical organ or organ system from which the specimens are being collected, and an identification panel, having a key for each chamber, allows commentary to be added regarding the particular samples. One or more non-site-specific chambers are also provided to allow the physician maximum collection flexibility, without the need for additional, separate containers. The chambers are filled with a tissue preservative to preserve the specimens for laboratory testing or histological examination.