Patents by Inventor Earl E. Henderson

Earl E. Henderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (2-5')-Oligo (3'-deoxyadenylate) and derivatives thereof
    Patent number: 4708935
    Abstract: 3'-deoxyadenosine 5'-triphosphate is oligomerized to form (2'-5')-oligo (3'-deoxyadenylate) by incubation with adenosine triphosphate: (2'-5')-oligo adenosine adenyl transferase, in the presence of an inert support carrying a double straded polynucleotide. The (2'-5')-oligo (3'-deoxyadenylate) is digested with a suitable phosphatase to remove the terminal phosphate groups. The thus produced corresponding 3'-deoxyadenosine compound is an anti-viral material effective against Herpes Simplex infection and effective in inhibiting the transformation of cells infected with Epstein Barr virus.
    Type: Grant
    Filed: March 29, 1985
    Date of Patent: November 24, 1987
    Assignee: Research Corporation
    Inventors: Robert J. Suhadolnik, Joseph M. Wu, Paul Doetsch, Earl E. Henderson
  • (2'-5')-Oligo (3'-deoxyandenylate) and derivatives thereof
    Patent number: 4539313
    Abstract: 3'-deoxyadenosine 5'-triphosphate is oligomerized to form (2'-5')-oligo (3'-deoxyadenylate) by incubation with adenosine triphosphate: (2'-5')-oligo adenosine adenyl transferase, in the presence of an inert support carrying a double stranded polynucleotide. The (2'-5')-oligo (3'-deoxyadenylate) is digested with a suitable phosphatase to remove the terminal phosphate groups. The thus produced corresponding 3'-deoxyadenosine compound is an anti-viral material effective against Herpes simplex infection and effective in inhibiting the transformation of cells infected with Epstein Barr virus.
    Type: Grant
    Filed: April 27, 1984
    Date of Patent: September 3, 1985
    Assignee: Research Corporation
    Inventors: Robert J. Suhadolnik, Joseph M. Wu, Paul Doetsch, Earl E. Henderson
  • (2'-5')-Oligo (3'-deoxyadenylate) and derivatives thereof
    Patent number: 4464359
    Abstract: 3'-Deoxyadenosine 5'-triphosphate is oligomerized to form (2'-5')-oligo (3'-deoxyadenylate) by incubation with adenosine triphosphate: (2'-5')-oligo adenosine adenyl transferase, in the presence of an inert support carrying a double stranded polynucleotide. The (2'-5')-oligo (3'-deoxyadenylate) is digested with a suitable phosphatase to remove the terminal phosphate groups. The thus produced corresponding 3'-deoxyadenosine compound is an anti-viral material effective against Herpes Simplex infection and effective in inhibiting the transformation of cells infected with Epstein Barr virus.
    Type: Grant
    Filed: April 10, 1981
    Date of Patent: August 7, 1984
    Assignee: Research Corporation
    Inventors: Robert J. Suhadolnik, Joseph M. Wu, Paul Doetsch, Earl E. Henderson