Patents by Inventor Eddy Yue

Eddy Yue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
    Patent number: 7250435
    Abstract: The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: July 31, 2007
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: David A. Nugiel, David J. Carini, Susan V. Di Meo, Anup P. Vidwans, Eddy Yue
  • Modulators of indoleamine 2,3-dioxygenase and methods of using the same
    Publication number: 20060258719
    Abstract: The present invention is directed to modulators of indoleamine 2,3-dioxygenase (IDO), as well as compositions and pharmaceutical methods thereof.
    Type: Application
    Filed: May 9, 2006
    Publication date: November 16, 2006
    Inventors: Andrew Combs, Eddy Yue
  • Inhibitors of proteins that bind phosphorylated molecules
    Publication number: 20050272778
    Abstract: The present invention provides compounds that can modulate the activity of a target protein, such as a phosphatase, that selectively binds phosphorylated peptides or proteins. The present compounds can be useful in treating diseases or disorders, including, for example, diabetes and obesity, that are connected directly or indirectly to the activity of the target protein.
    Type: Application
    Filed: October 7, 2004
    Publication date: December 8, 2005
    Inventors: Andrew Combs, Eddy Yue, Michael Bower, Wenyu Zhu, Matthew Crawley, Richard Sparks, James Pruitt, Amy Takvorian
  • Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
    Publication number: 20050261353
    Abstract: The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.
    Type: Application
    Filed: February 24, 2005
    Publication date: November 24, 2005
    Inventors: David Nugiel, David Carini, Susan Di Meo, Anup Vidwans, Eddy Yue
  • Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
    Publication number: 20040048844
    Abstract: The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): 1
    Type: Application
    Filed: May 1, 2003
    Publication date: March 11, 2004
    Applicant: Bristol-Myers Squibb Pharma Company
    Inventors: David Nugiel, David Carini, Susan DiMeo, Anup Vidwans, Eddy Yue
  • Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
    Patent number: 6593356
    Abstract: The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: July 15, 2003
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: David Nugiel, David Carini, Susan DiMeo, Anup Vidwans, Eddy Yue
  • Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
    Publication number: 20030073686
    Abstract: The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): 1
    Type: Application
    Filed: July 16, 2001
    Publication date: April 17, 2003
    Inventors: David Nugiel, David Carini, Susan DiMeo, Anup Vidwans, Eddy Yue