Patents by Inventor Eden Rephaeli

Eden Rephaeli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10473911
    Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor is configured to receive a reflection of the visible light as reflected visible light.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: November 12, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
  • Patent number: 10445607
    Abstract: An imaging system (e.g., hyperspectral imaging system) receives an indication to compare a first object and a second object (e.g., two anatomical structures or organs in a medical environment). The imaging system accesses a classification vector for the first object and the second object, the classification vector having been extracted by separating a plurality of collected reflectance values for the first object from a plurality of collected reflectance values for the second object. A set of optimal illumination intensities for one or more spectral illumination sources of the imaging system is determined based on the extracted classification vector. The first and second objects are illuminated with the determined illumination intensities. A high-contrast image of the first and second objects is provided for display, such that the two objects can be readily distinguished in the image. The intensity of pixels in the image is determined by the illumination intensities.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: October 15, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Vidya Ganapati, Daniele Piponi, Thomas Teisseyre
  • Patent number: 10440300
    Abstract: Systems and methods are described that relate to an optical system including an image sensor optically-coupled to at least one nanophotonic element. The image sensor may include a plurality of superpixels. Each respective superpixel of the plurality of superpixels may include at least a respective first pixel and a respective second pixel. The at least one nanophotonic element may have an optical phase transfer function and may include a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first material having a first index of refraction and the second material having a second index of refraction. The nanophotonic element is configured to direct light toward individual superpixels in the plurality of superpixels, and to direct light toward the first or second pixel in each individual superpixel based on a wavelength dependence or a polarization dependence of the optical phase transfer function.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: October 8, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Victor Marcel Acosta, Andrew Homyk
  • Patent number: 10410365
    Abstract: An apparatus, system and process for utilizing dual complementary pattern illumination of a scene when performing depth reconstruction of the scene are described. The method may include projecting a first reference image and a complementary second reference image on a scene, and capturing first image data and second image data including the first reference image and the complementary second reference image on the scene. The method may also include identifying features of the first reference image from features of the complementary second reference image. Furthermore, the method may include performing three dimensional (3D) scene reconstruction for image data captured by the imaging device based on the identified features in the first reference image.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: September 10, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Vidya Ganapati, Eden Rephaeli
  • Patent number: 10386627
    Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor coupled to the distal end of the fiber optic cable and positioned to receive a reflection of the visible light as reflected visible light.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: August 20, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
  • Publication number: 20190246905
    Abstract: Systems and methods for acquiring images of a sample are provided. According to an aspect of the invention, a system includes a first light source that emits first light having a first wavelength as a temporally continuous beam; a second light source that emits second light having a second wavelength as a temporally modulated beam; and a scanning mirror that raster scans the first light across a sample during a raster scan period, and projects a structured light pattern of the second light onto the sample during the raster scan period. A first image of the sample is generated from at least a portion of the first light that is backscattered from the sample during the raster scan period, and a second image of the sample is generated from at least a portion of the second light that is backscattered from the sample during the raster scan period.
    Type: Application
    Filed: January 23, 2019
    Publication date: August 15, 2019
    Applicant: Verily Life Sciences LLC
    Inventors: Chinmay Belthangady, James Polans, Daniele Piponi, Eden Rephaeli
  • Publication number: 20190250394
    Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor is configured to receive a reflection of the visible light as reflected visible light.
    Type: Application
    Filed: April 24, 2019
    Publication date: August 15, 2019
    Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
  • Patent number: 10375330
    Abstract: The present disclosure relates to systems and devices configured to determine the distance to objects within a field of view. Namely, at least a portion of the field of view may be illuminated with a coherent light source. Due to interactions between the laser light, the transmission medium, and the object, characteristic laser speckle patterns may be formed. These characteristic laser speckle patterns may be imaged with a camera. Using statistical image analysis, an estimated distance to the objects within the field of view may be obtained. For example, the image frame may be partitioned into a plurality of image segments. An autocorrelation for each image segment of the plurality of image segments may be obtained. A depth map may be obtained based on the autocorrelations.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: August 6, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Daniele Paolo Piponi
  • Patent number: 10338275
    Abstract: Systems and methods are described that relate to a nanophotonic optical system. The nanophotonic optical system may be configured to transmit light in a range of wavelengths. The nanophotonic optical system includes at least one nanophotonic element, which includes a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first and second materials having different indices of refraction. The at least one nanophotonic element includes a surface having a curvature and an optical phase transfer function dependent on the curvature of the surface. The nanophotonic optical system includes an actuator configured to modify the curvature of the surface and a controller. The controller is configured to determine a threshold optical phase transfer function and cause the actuator to modify the curvature of the surface to provide the threshold optical phase transfer function.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: July 2, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Victor Marcel Acosta, James Michael Higbie, Supriyo Sinha, Eden Rephaeli, Andrew Homyk, John D. Perreault
  • Patent number: 10259126
    Abstract: A device for relief of strain on a cable includes a modular base for mounting, a first arm, a second arm, and a spring assembly. The first arm is pivotally coupled to the modular base. A first proximal end of the first arm is connected to the modular base at a first pivot point for pivoting of the first arm about a first rotational axis. The second arm is coupled to the modular base. A second proximal end of the second arm is connected to the modular base. The spring assembly is coupled to the first arm to provide a clamping force between the first arm and the second arm.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: April 16, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Maximilian Kapczynski, Eden Rephaeli
  • Publication number: 20190105787
    Abstract: A device for relief of strain on a cable includes a modular base for mounting, a first arm, a second arm, and a spring assembly. The first arm is pivotally coupled to the modular base. A first proximal end of the first arm is connected to the modular base at a first pivot point for pivoting of the first arm about a first rotational axis. The second arm is coupled to the modular base. A second proximal end of the second arm is connected to the modular base. The spring assembly is coupled to the first arm to provide a clamping force between the first arm and the second arm.
    Type: Application
    Filed: October 10, 2017
    Publication date: April 11, 2019
    Inventors: Maximilian Kapczynski, Eden Rephaeli
  • Publication number: 20190065905
    Abstract: Embodiments may include a method to estimate motion data based on test image data sets. The method may include receiving a training data set comprising a plurality of training data elements. Each element may include an image data set and a motion data set. The method may include training a machine learning model using the training data set, resulting in identifying one or more parameters of a function in the machine learning model based on correspondences between the image data sets and the motion data sets. The method may further include receiving a test image data set. The test image data set may include intensities of pixels in a deep-tissue image. The method may include using the trained machine learning model and the test image data set to generate output data for the test image data set. The output data may characterize motion represented in the test image data set.
    Type: Application
    Filed: August 13, 2018
    Publication date: February 28, 2019
    Applicant: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Daniele Piponi, Chinmay Belthangady, Seung Ah Lee
  • Publication number: 20190017758
    Abstract: Various aspects as described herein are directed to a radiative cooling apparatuses and methods for cooling an object. As consistent with one or more embodiments, a radiative cooling apparatus includes an arrangement of a plurality of different material located at different depths along a depth dimension relative to the object. The plurality of different material includes a solar spectrum reflecting portion configured and arranged to suppress light modes, thereby inhibiting coupling of the incoming electromagnetic radiation, of at least some wavelengths in the solar spectrum, to the object at a range of angles of incidence relative to the depth dimension. Further, the plurality of material includes a thermally-emissive arrangement configured and arranged to facilitate, simultaneously with the inhibiting coupling of the incoming electromagnetic radiation, the thermally-generated electromagnetic emissions from the object at the range of angles of incidence and in mid-IR wavelengths.
    Type: Application
    Filed: September 19, 2018
    Publication date: January 17, 2019
    Inventors: Aaswath Pattabhi Raman, Shanhui Fan, Eden Rephaeli, Linxiao Zhu, Marc A. Anoma, Eli Goldstein
  • Publication number: 20180316880
    Abstract: Systems and methods are described that relate to an optical system including an image sensor optically-coupled to at least one nanophotonic element. The image sensor may include a plurality of superpixels. Each respective superpixel of the plurality of superpixels may include at least a respective first pixel and a respective second pixel. The at least one nanophotonic element may have an optical phase transfer function and may include a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first material having a first index of refraction and the second material having a second index of refraction. The nanophotonic element is configured to direct light toward individual superpixels in the plurality of superpixels, and to direct light toward the first or second pixel in each individual superpixel based on a wavelength dependence or a polarization dependence of the optical phase transfer function.
    Type: Application
    Filed: July 5, 2018
    Publication date: November 1, 2018
    Inventors: Eden Rephaeli, Victor Marcel Acosta, Andrew Homyk
  • Publication number: 20180296270
    Abstract: In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore. A beam scanner may direct the excitation light towards a tissue location. A fluorophore may produce emission light in response to absorbing the excitation light. A camera may capture an image of the tissue location. In response to the image indicating emission light at the tissue location, an ablation light source may produce ablation light. The beam scanner may direct the ablation light towards the tissue location. Additionally or alternatively, a topography map may be generated and certain aspects of the apparatus and/or the method may be adjusted based on the topography map.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Inventors: Eden Rephaeli, Chia-Jean Wang
  • Patent number: 10092355
    Abstract: A surgical probe is configured to be inserted into a body cavity and to emit beams of light to ablate tissue within the body cavity. The probe further includes sensors to detect properties of tissue in the body cavity and a source of suction to remove material produced by ablation of tissue within the body cavity. The sensors could be configured to operate in combination with beams of light emitted by the surgical probe to detect the location, geometry, fluorophore content, or other information about tissue in the body cavity. The surgical probe can additionally include suction port(s) to secure portions of tissue relative to the surgical probe to allow ablation of portions of the secured tissue and to allow detection of properties of portions of the secured tissue that are maintained in contact with the surgical probe by the suction port(s).
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: October 9, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Blake Eugene Hannaford, Eden Rephaeli, Jöelle Karine Barral, Christine Denise Ching
  • Patent number: 10088251
    Abstract: Various aspects as described herein are directed to a radiative cooling apparatuses and methods for cooling an object. As consistent with one or more embodiments, a radiative cooling apparatus includes an arrangement of a plurality of different material located at different depths along a depth dimension relative to the object. The plurality of different material includes a solar spectrum reflecting portion configured and arranged to suppress light modes, thereby inhibiting coupling of the incoming electromagnetic radiation, of at least some wavelengths in the solar spectrum, to the object at a range of angles of incidence relative to the depth dimension. Further, the plurality of material includes a thermally-emissive arrangement configured and arranged to facilitate, simultaneously with the inhibiting coupling of the incoming electromagnetic radiation, the thermally-generated electromagnetic emissions from the object at the range of angles of incidence and in mid-IR wavelengths.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: October 2, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Aaswath Pattabhi Raman, Shanhui Fan, Eden Rephaeli, Linxiao Zhu, Marc Anoma, Eli Goldstein
  • Publication number: 20180247153
    Abstract: An apparatus, system and process for identifying one or more different tissue types are described. The method may include applying a configuration to one or more programmable light sources of an imaging system, where the configuration is obtained from a machine learning model trained to distinguish between the one or more different tissue types captured in image data. The method may also include illuminating a scene with the configured one or more programmable light sources, and capturing image data that includes one or more types of tissue depicted in the image data. Furthermore, the method may include analyzing color information in the captured image data with the machine learning model to identify at least one of the one or more different tissue types in the image data, and rendering a visualization of the scene from the captured image data that visually differentiates tissue types in the visualization.
    Type: Application
    Filed: February 28, 2017
    Publication date: August 30, 2018
    Inventors: Vidya Ganapati, Eden Rephaeli
  • Patent number: 10052154
    Abstract: In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore. A beam scanner may direct the excitation light towards a tissue location. A fluorophore may produce emission light in response to absorbing the excitation light. A camera may capture an image of the tissue location. In response to the image indicating emission light at the tissue location, an ablation light source may produce ablation light. The beam scanner may direct the ablation light towards the tissue location. Additionally or alternatively, a topography map may be generated and certain aspects of the apparatus and/or the method may be adjusted based on the topography map.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: August 21, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Eden Rephaeli, Chia-Jean Wang
  • Publication number: 20180210188
    Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor coupled to the distal end of the fiber optic cable and positioned to receive a reflection of the visible light as reflected visible light.
    Type: Application
    Filed: January 20, 2017
    Publication date: July 26, 2018
    Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi