Patents by Inventor Eden Rephaeli
Eden Rephaeli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10473911Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor is configured to receive a reflection of the visible light as reflected visible light.Type: GrantFiled: April 24, 2019Date of Patent: November 12, 2019Assignee: Verily Life Sciences LLCInventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
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Patent number: 10445607Abstract: An imaging system (e.g., hyperspectral imaging system) receives an indication to compare a first object and a second object (e.g., two anatomical structures or organs in a medical environment). The imaging system accesses a classification vector for the first object and the second object, the classification vector having been extracted by separating a plurality of collected reflectance values for the first object from a plurality of collected reflectance values for the second object. A set of optimal illumination intensities for one or more spectral illumination sources of the imaging system is determined based on the extracted classification vector. The first and second objects are illuminated with the determined illumination intensities. A high-contrast image of the first and second objects is provided for display, such that the two objects can be readily distinguished in the image. The intensity of pixels in the image is determined by the illumination intensities.Type: GrantFiled: March 16, 2017Date of Patent: October 15, 2019Assignee: Verily Life Sciences LLCInventors: Eden Rephaeli, Vidya Ganapati, Daniele Piponi, Thomas Teisseyre
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Patent number: 10440300Abstract: Systems and methods are described that relate to an optical system including an image sensor optically-coupled to at least one nanophotonic element. The image sensor may include a plurality of superpixels. Each respective superpixel of the plurality of superpixels may include at least a respective first pixel and a respective second pixel. The at least one nanophotonic element may have an optical phase transfer function and may include a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first material having a first index of refraction and the second material having a second index of refraction. The nanophotonic element is configured to direct light toward individual superpixels in the plurality of superpixels, and to direct light toward the first or second pixel in each individual superpixel based on a wavelength dependence or a polarization dependence of the optical phase transfer function.Type: GrantFiled: July 5, 2018Date of Patent: October 8, 2019Assignee: Verily Life Sciences LLCInventors: Eden Rephaeli, Victor Marcel Acosta, Andrew Homyk
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Patent number: 10410365Abstract: An apparatus, system and process for utilizing dual complementary pattern illumination of a scene when performing depth reconstruction of the scene are described. The method may include projecting a first reference image and a complementary second reference image on a scene, and capturing first image data and second image data including the first reference image and the complementary second reference image on the scene. The method may also include identifying features of the first reference image from features of the complementary second reference image. Furthermore, the method may include performing three dimensional (3D) scene reconstruction for image data captured by the imaging device based on the identified features in the first reference image.Type: GrantFiled: April 13, 2017Date of Patent: September 10, 2019Assignee: Verily Life Sciences LLCInventors: Vidya Ganapati, Eden Rephaeli
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Patent number: 10386627Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor coupled to the distal end of the fiber optic cable and positioned to receive a reflection of the visible light as reflected visible light.Type: GrantFiled: January 20, 2017Date of Patent: August 20, 2019Assignee: Verily Life Sciences LLCInventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
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Publication number: 20190246905Abstract: Systems and methods for acquiring images of a sample are provided. According to an aspect of the invention, a system includes a first light source that emits first light having a first wavelength as a temporally continuous beam; a second light source that emits second light having a second wavelength as a temporally modulated beam; and a scanning mirror that raster scans the first light across a sample during a raster scan period, and projects a structured light pattern of the second light onto the sample during the raster scan period. A first image of the sample is generated from at least a portion of the first light that is backscattered from the sample during the raster scan period, and a second image of the sample is generated from at least a portion of the second light that is backscattered from the sample during the raster scan period.Type: ApplicationFiled: January 23, 2019Publication date: August 15, 2019Applicant: Verily Life Sciences LLCInventors: Chinmay Belthangady, James Polans, Daniele Piponi, Eden Rephaeli
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Publication number: 20190250394Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor is configured to receive a reflection of the visible light as reflected visible light.Type: ApplicationFiled: April 24, 2019Publication date: August 15, 2019Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi
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Patent number: 10375330Abstract: The present disclosure relates to systems and devices configured to determine the distance to objects within a field of view. Namely, at least a portion of the field of view may be illuminated with a coherent light source. Due to interactions between the laser light, the transmission medium, and the object, characteristic laser speckle patterns may be formed. These characteristic laser speckle patterns may be imaged with a camera. Using statistical image analysis, an estimated distance to the objects within the field of view may be obtained. For example, the image frame may be partitioned into a plurality of image segments. An autocorrelation for each image segment of the plurality of image segments may be obtained. A depth map may be obtained based on the autocorrelations.Type: GrantFiled: May 11, 2017Date of Patent: August 6, 2019Assignee: Verily Life Sciences LLCInventors: Eden Rephaeli, Daniele Paolo Piponi
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Patent number: 10338275Abstract: Systems and methods are described that relate to a nanophotonic optical system. The nanophotonic optical system may be configured to transmit light in a range of wavelengths. The nanophotonic optical system includes at least one nanophotonic element, which includes a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first and second materials having different indices of refraction. The at least one nanophotonic element includes a surface having a curvature and an optical phase transfer function dependent on the curvature of the surface. The nanophotonic optical system includes an actuator configured to modify the curvature of the surface and a controller. The controller is configured to determine a threshold optical phase transfer function and cause the actuator to modify the curvature of the surface to provide the threshold optical phase transfer function.Type: GrantFiled: May 27, 2016Date of Patent: July 2, 2019Assignee: Verily Life Sciences LLCInventors: Victor Marcel Acosta, James Michael Higbie, Supriyo Sinha, Eden Rephaeli, Andrew Homyk, John D. Perreault
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Patent number: 10259126Abstract: A device for relief of strain on a cable includes a modular base for mounting, a first arm, a second arm, and a spring assembly. The first arm is pivotally coupled to the modular base. A first proximal end of the first arm is connected to the modular base at a first pivot point for pivoting of the first arm about a first rotational axis. The second arm is coupled to the modular base. A second proximal end of the second arm is connected to the modular base. The spring assembly is coupled to the first arm to provide a clamping force between the first arm and the second arm.Type: GrantFiled: October 10, 2017Date of Patent: April 16, 2019Assignee: Verily Life Sciences LLCInventors: Maximilian Kapczynski, Eden Rephaeli
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Publication number: 20190105787Abstract: A device for relief of strain on a cable includes a modular base for mounting, a first arm, a second arm, and a spring assembly. The first arm is pivotally coupled to the modular base. A first proximal end of the first arm is connected to the modular base at a first pivot point for pivoting of the first arm about a first rotational axis. The second arm is coupled to the modular base. A second proximal end of the second arm is connected to the modular base. The spring assembly is coupled to the first arm to provide a clamping force between the first arm and the second arm.Type: ApplicationFiled: October 10, 2017Publication date: April 11, 2019Inventors: Maximilian Kapczynski, Eden Rephaeli
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Publication number: 20190065905Abstract: Embodiments may include a method to estimate motion data based on test image data sets. The method may include receiving a training data set comprising a plurality of training data elements. Each element may include an image data set and a motion data set. The method may include training a machine learning model using the training data set, resulting in identifying one or more parameters of a function in the machine learning model based on correspondences between the image data sets and the motion data sets. The method may further include receiving a test image data set. The test image data set may include intensities of pixels in a deep-tissue image. The method may include using the trained machine learning model and the test image data set to generate output data for the test image data set. The output data may characterize motion represented in the test image data set.Type: ApplicationFiled: August 13, 2018Publication date: February 28, 2019Applicant: Verily Life Sciences LLCInventors: Eden Rephaeli, Daniele Piponi, Chinmay Belthangady, Seung Ah Lee
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Publication number: 20190017758Abstract: Various aspects as described herein are directed to a radiative cooling apparatuses and methods for cooling an object. As consistent with one or more embodiments, a radiative cooling apparatus includes an arrangement of a plurality of different material located at different depths along a depth dimension relative to the object. The plurality of different material includes a solar spectrum reflecting portion configured and arranged to suppress light modes, thereby inhibiting coupling of the incoming electromagnetic radiation, of at least some wavelengths in the solar spectrum, to the object at a range of angles of incidence relative to the depth dimension. Further, the plurality of material includes a thermally-emissive arrangement configured and arranged to facilitate, simultaneously with the inhibiting coupling of the incoming electromagnetic radiation, the thermally-generated electromagnetic emissions from the object at the range of angles of incidence and in mid-IR wavelengths.Type: ApplicationFiled: September 19, 2018Publication date: January 17, 2019Inventors: Aaswath Pattabhi Raman, Shanhui Fan, Eden Rephaeli, Linxiao Zhu, Marc A. Anoma, Eli Goldstein
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Publication number: 20180316880Abstract: Systems and methods are described that relate to an optical system including an image sensor optically-coupled to at least one nanophotonic element. The image sensor may include a plurality of superpixels. Each respective superpixel of the plurality of superpixels may include at least a respective first pixel and a respective second pixel. The at least one nanophotonic element may have an optical phase transfer function and may include a two-dimensional arrangement of sub-wavelength regions of a first material interspersed within a second material, the first material having a first index of refraction and the second material having a second index of refraction. The nanophotonic element is configured to direct light toward individual superpixels in the plurality of superpixels, and to direct light toward the first or second pixel in each individual superpixel based on a wavelength dependence or a polarization dependence of the optical phase transfer function.Type: ApplicationFiled: July 5, 2018Publication date: November 1, 2018Inventors: Eden Rephaeli, Victor Marcel Acosta, Andrew Homyk
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Publication number: 20180296270Abstract: In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore. A beam scanner may direct the excitation light towards a tissue location. A fluorophore may produce emission light in response to absorbing the excitation light. A camera may capture an image of the tissue location. In response to the image indicating emission light at the tissue location, an ablation light source may produce ablation light. The beam scanner may direct the ablation light towards the tissue location. Additionally or alternatively, a topography map may be generated and certain aspects of the apparatus and/or the method may be adjusted based on the topography map.Type: ApplicationFiled: June 26, 2018Publication date: October 18, 2018Inventors: Eden Rephaeli, Chia-Jean Wang
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Patent number: 10092355Abstract: A surgical probe is configured to be inserted into a body cavity and to emit beams of light to ablate tissue within the body cavity. The probe further includes sensors to detect properties of tissue in the body cavity and a source of suction to remove material produced by ablation of tissue within the body cavity. The sensors could be configured to operate in combination with beams of light emitted by the surgical probe to detect the location, geometry, fluorophore content, or other information about tissue in the body cavity. The surgical probe can additionally include suction port(s) to secure portions of tissue relative to the surgical probe to allow ablation of portions of the secured tissue and to allow detection of properties of portions of the secured tissue that are maintained in contact with the surgical probe by the suction port(s).Type: GrantFiled: November 21, 2014Date of Patent: October 9, 2018Assignee: Verily Life Sciences LLCInventors: Blake Eugene Hannaford, Eden Rephaeli, Jöelle Karine Barral, Christine Denise Ching
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Patent number: 10088251Abstract: Various aspects as described herein are directed to a radiative cooling apparatuses and methods for cooling an object. As consistent with one or more embodiments, a radiative cooling apparatus includes an arrangement of a plurality of different material located at different depths along a depth dimension relative to the object. The plurality of different material includes a solar spectrum reflecting portion configured and arranged to suppress light modes, thereby inhibiting coupling of the incoming electromagnetic radiation, of at least some wavelengths in the solar spectrum, to the object at a range of angles of incidence relative to the depth dimension. Further, the plurality of material includes a thermally-emissive arrangement configured and arranged to facilitate, simultaneously with the inhibiting coupling of the incoming electromagnetic radiation, the thermally-generated electromagnetic emissions from the object at the range of angles of incidence and in mid-IR wavelengths.Type: GrantFiled: May 21, 2015Date of Patent: October 2, 2018Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Aaswath Pattabhi Raman, Shanhui Fan, Eden Rephaeli, Linxiao Zhu, Marc Anoma, Eli Goldstein
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Publication number: 20180247153Abstract: An apparatus, system and process for identifying one or more different tissue types are described. The method may include applying a configuration to one or more programmable light sources of an imaging system, where the configuration is obtained from a machine learning model trained to distinguish between the one or more different tissue types captured in image data. The method may also include illuminating a scene with the configured one or more programmable light sources, and capturing image data that includes one or more types of tissue depicted in the image data. Furthermore, the method may include analyzing color information in the captured image data with the machine learning model to identify at least one of the one or more different tissue types in the image data, and rendering a visualization of the scene from the captured image data that visually differentiates tissue types in the visualization.Type: ApplicationFiled: February 28, 2017Publication date: August 30, 2018Inventors: Vidya Ganapati, Eden Rephaeli
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Patent number: 10052154Abstract: In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore. A beam scanner may direct the excitation light towards a tissue location. A fluorophore may produce emission light in response to absorbing the excitation light. A camera may capture an image of the tissue location. In response to the image indicating emission light at the tissue location, an ablation light source may produce ablation light. The beam scanner may direct the ablation light towards the tissue location. Additionally or alternatively, a topography map may be generated and certain aspects of the apparatus and/or the method may be adjusted based on the topography map.Type: GrantFiled: October 1, 2014Date of Patent: August 21, 2018Assignee: Verily Life Sciences LLCInventors: Eden Rephaeli, Chia-Jean Wang
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Publication number: 20180210188Abstract: An endoscope apparatus includes a fiber optic cable with a proximal end and a distal end opposite the proximal end. The endoscope apparatus also includes a light source optically coupled to the proximal end of the fiber optic cable to emit visible light and excitation light into the fiber optic cable for output from the distal end. The light source is configured to emit both the visible light and the excitation light simultaneously, and a wavelength of the excitation light is outside a wavelength spectrum of the visible light. An image sensor coupled to the distal end of the fiber optic cable and positioned to receive a reflection of the visible light as reflected visible light.Type: ApplicationFiled: January 20, 2017Publication date: July 26, 2018Inventors: Vidya Ganapati, Eden Rephaeli, Daniele Piponi