Patents by Inventor EDNA CHOW MANEVAL

EDNA CHOW MANEVAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER
    Publication number: 20220257592
    Abstract: Provided herein are methods of treating cancer in a patient in need thereof includes administering to the patient a therapeutically effective amount of entrectinib wherein the patient has impaired hepatic function and methods of managing adverse reactions of administration of entrectinib in a patient.
    Type: Application
    Filed: February 1, 2022
    Publication date: August 18, 2022
    Applicants: HOFFMANN-LA ROCHE INC., IGNYTA, INC., GENENTECH, INC.
    Inventors: Georgina Meneses-Lorente, Edna Chow Maneval, Pratik S. Multani, Susan Diane Eng, Sergio Rene Ley Acosta
  • Androgen Receptor Modulator And Uses Thereof
    Publication number: 20210177821
    Abstract: Described herein is the androgen receptor modulator of formula (I) in the treatment of prostate cancer in combination with other therapeutic options and in the treatment of diseases or conditions that are amenable to treatment with the androgen receptor modulator, as well as pharmaceutical compositions and medicaments that include such compound.
    Type: Application
    Filed: February 25, 2021
    Publication date: June 17, 2021
    Inventors: Isan Chen, Jeffrey H. Hager, Edna Chow Maneval, Mark R. Herbert, Nicholas D. Smith
  • Estrogen receptor modulators and uses thereof
    Patent number: 10227334
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: March 12, 2019
    Assignee: Genentech, Inc.
    Inventors: Mehmet Kahraman, Steven P. Govek, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer
    Patent number: 10034860
    Abstract: Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: July 31, 2018
    Assignee: Genentech, Inc.
    Inventors: Edna Chow Maneval, Boa Tran H. Troung, Isan Chen, Jeffrey H. Hager, Debasish F. Roychowdhury
  • Estrogen receptor modulators and uses thereof
    Patent number: 9873684
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: January 23, 2018
    Assignee: Genentech, Inc.
    Inventors: Mehmet Kahraman, Steven P. Govek, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • Methods and compositions for modulating estrogen receptor mutants
    Patent number: 9855270
    Abstract: Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: January 2, 2018
    Assignee: GENENTECH, INC.
    Inventors: Jeffrey J. Hager, James D. Joseph, Jing Qian, Nicholas D. Smith, Edna Chow Maneval, Debasish F. Roychowdhury, Lori Friedman, Deepak Sampath
  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20170275273
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: June 12, 2017
    Publication date: September 28, 2017
    Applicant: Genentech, Inc.
    Inventors: Mehmet Kahraman, Steven P. Govek, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • ESTROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF LOCALLY ADVANCED OR METASTATIC ESTROGEN RECEPTOR POSITIVE BREAST CANCER
    Publication number: 20170239219
    Abstract: Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Applicant: Genentech, Inc.
    Inventors: Edna Chow Maneval, Boa Tran H. Troung, Isan Chen, Jeffrey H. Hager, Debasish F. Roychowdhury
  • Estrogen receptor modulator for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer
    Patent number: 9675586
    Abstract: Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: June 13, 2017
    Assignee: Genentech, Inc.
    Inventors: Edna Chow Maneval, Boa Tran H. Truong, Isan Chen, Jeffrey H. Hager, Debasish F. Roychowdhury
  • Azetidine estrogen receptor modulators and uses thereof
    Patent number: 9655880
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: May 23, 2017
    Assignee: Genentech, Inc.
    Inventors: Steven P. Govek, Mehmet Kahraman, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • AZETIDINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160367526
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: September 6, 2016
    Publication date: December 22, 2016
    Applicant: Genentech, Inc.
    Inventors: Steven P. Govek, Mehmet Kahraman, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • Azetidine estrogen receptor modulators and uses thereof
    Patent number: 9475798
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: October 25, 2016
    Assignee: Genentech, Inc.
    Inventors: Steven P. Govek, Mehmet Kahraman, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • ANDROGEN RECEPTOR MODULATOR AND USES THEREOF
    Publication number: 20160220548
    Abstract: Described herein is the androgen receptor modulator of formula (I) in the treatment of prostate cancer in combination with other therapeutic options and in the treatment of diseases or conditions that are amenable to treatment with the androgen receptor modulator, as well as pharmaceutical compositions and medicaments that include such compound.
    Type: Application
    Filed: April 8, 2016
    Publication date: August 4, 2016
    Inventors: ISAN CHEN, JEFFREY H. HAGER, EDNA CHOW MANEVAL, MARK R. HERBERT, NICHOLAS D. SMITH
  • Androgen receptor modulator and uses thereof
    Patent number: 9340524
    Abstract: Described herein is the androgen receptor modulator of formula (I) in the treatment of prostate cancer in combination with other therapeutic options and in the treatment of diseases or conditions that are amenable to treatment with the androgen receptor modulator, as well as pharmaceutical compositions and medicaments that include such compound.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: May 17, 2016
    Assignee: Aragon Pharmaceuticals, Inc.
    Inventors: Isan Chen, Jeffrey H Hager, Edna Chow Maneval, Mark R Herbert, Nicholas D Smith
  • AZETIDINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160090377
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Applicant: Genentech, Inc.
    Inventors: Steven P. Govek, Mehmet Kahraman, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20160090378
    Abstract: Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Applicant: Genentech, Inc.
    Inventors: Mehmet Kahraman, Steven P. Govek, Nicholas D. Smith, Jeffrey H. Hager, Edna Chow Maneval
  • THERAPEUTIC COMBINATIONS WITH ESTROGEN RECEPTOR MODULATORS
    Publication number: 20150258080
    Abstract: Described herein are therapeutic combinations with estrogen receptor modulators for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 17, 2015
    Applicant: Genentech, Inc.
    Inventors: Jeffrey J. Hager, Edna Chow Maneval, Nicholas D. Smith, Lori Friedman, Deepak Sampath
  • METHODS AND COMPOSITIONS FOR MODULATING ESTROGEN RECEPTOR MUTANTS
    Publication number: 20150258099
    Abstract: Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.
    Type: Application
    Filed: March 12, 2015
    Publication date: September 17, 2015
    Applicant: GENENTECH, INC.
    Inventors: Jeffrey J. Hager, James D. Joseph, Jing Qian, Nicholas D. Smith, Edna Chow Maneval, Debasish F. ROYCHOWDHURY, Lori Friedman, Deepak Sampath
  • ESTROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF LOCALLY ADVANCED OR METASTATIC ESTROGEN RECEPTOR POSITIVE BREAST CANCER
    Publication number: 20150157606
    Abstract: Described herein are methods of treating locally advanced or metastatic estrogen receptor positive breast cancer.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 11, 2015
    Inventors: Edna Chow Maneval, Boa Tran H. Truong, Isan Chen, Jeffrey H. Hager, Debasish F. Roychowdhury
  • ANDROGEN RECEPTOR MODULATOR AND USES THEREOF
    Publication number: 20140199236
    Abstract: Described herein is the androgen receptor modulator of formula (I) in the treatment of prostate cancer in combination with other therapeutic options and in the treatment of diseases or conditions that are amenable to treatment with the androgen receptor modulator, as well as pharmaceutical compositions and medicaments that include such compound.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 17, 2014
    Applicant: ARAGON PHARMACEUTICALS, INC.
    Inventors: ISAN CHEN, JEFFREY H. HAGER, EDNA CHOW MANEVAL, MARK R. HERBERT, NICHOLAS D. SMITH