Patents by Inventor Eduard Batlle Gomez

Eduard Batlle Gomez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TGFß INHIBITOR AND PRODRUGS
    Publication number: 20220089600
    Abstract: A compound of formula I with improved TGF? signaling pathway inhibitory activity, improved therapeutic efficacy and improved toxicity profile, as well as two prodrugs thereof are disclosed. Compositions comprising said TGF? signaling pathway inhibitor and prodrugs thereof are also disclosed. Additionally, present invention discloses said compound of formula I and prodrugs thereof for use in a method of treating diseases responsive to TGF? signaling pathway inhibition.
    Type: Application
    Filed: November 22, 2019
    Publication date: March 24, 2022
    Inventors: Daniele TAURIELLO, Daniel BYROM, Joan Antoni MATARÍN MORALES, Eduard BATLLE GÓMEZ, Antoni RIERA ESCALÉ
  • METHODS AND KITS FOR THE PROGNOSIS OF COLORECTAL CANCER
    Publication number: 20150289795
    Abstract: The invention relates to methods for predicting the risk of relapse of cancer patients as well as methods for providing personalized medicine to said patients based on the expression levels of different genes the expression of which is induced in response to TGF-beta stimulation. The invention also relates to kits for carrying out the diagnostic and predictive medicine methods.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 15, 2015
    Inventors: Eduard Batlle Gómez, Elena Sancho Suils, David Rossell Ribera, Alexandre Calon, Elisa Espinet Hernández, Sergio Palomo Ponce
  • METHODS AND KITS FOR THE PROGNOSIS OF COLORECTAL CANCER
    Publication number: 20140314662
    Abstract: The invention relates to methods for predicting the risk of relapse of cancer patients as well as methods for providing personalized medicine to said patients based on the expression levels of different genes the expression of which is induced in response to TGF-beta stimulation. The invention also relates to kits for carrying out the diagnostic and predictive medicine methods.
    Type: Application
    Filed: November 12, 2012
    Publication date: October 23, 2014
    Inventors: Eduard Batlle-Gomez, Elena Sancho Suils, David Rossell Ribera, Alexandre Calon, Elisa Espinet Hernandez, Sergio Palomo Ponce
  • Use of novel stem cell markers for isolation of intestinal stem cells, and use of the intestinal stem cells thus obtained for the preparation of a therapeutical composition
    Publication number: 20040058392
    Abstract: The invention relates to the use of the expression products of the TCF target genes as markers for the isolation of intestinal stem cells in a method for the isolation of intestinal stem cells by providing antibodies, antibody derivatives or ligand fusion proteins against one or more of the target gene products of the genes; providing single cell suspensions of intestinal tissue; contacting the antibodies, antibody derivatives or ligand fusion proteins and the single cell suspensions; identifying the cells binding to the antibodies, antibody derivatives or ligand fusion proteins; and optionally isolating the stem cells from the antibodies, antibody derivatives or ligand fusion proteins.
    Type: Application
    Filed: September 17, 2002
    Publication date: March 25, 2004
    Applicant: Kylix B.V.
    Inventors: Johannes Carolus Clevers, Eduard Batlle Gomez, Marcus Lambertus Van De Wetering, Elena Sancho Suils