Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: Systems and methods for rewarding users of a social network are disclosed. In embodiments, a social networking system receives a first user's prediction regarding an event, series of events, or portion of an event, as well as the first user's reasoning supporting the prediction. In certain embodiments, the social networking system then receives feedback—for example, in the form of a vote of approval—from one or more users regarding the information received from the first user. According to some embodiments, reward amounts for the first user and the feedback-providing users are then calculated based on at least the feedback and the outcome of the event, series of events, or portion of an event, the first user's prediction is about.

Abstract: An automated system and method for processing vote-by-mail ballots. The method comprises electronically evaluating the ballots for validity and sorting them according to sort parameters and sort plan. Included in the invention is an apparatus, computer readable medium, and computer system for carrying out the ballot processing method.

Abstract: An automated system and method for processing vote-by-mail ballots. The method comprises electronically evaluating the ballots for validity and sorting them according to sort parameters and sort plan. Included in the invention is an apparatus, computer readable medium, and computer system for carrying out the ballot processing method.

Abstract: Methods useful in constructing libraries that collectively display and/or express members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.

Abstract: Methods useful in constructing libraries that collectively display members of diverse families of peptides, polypeptides or proteins and the libraries produced using those methods. Methods of screening those libraries and the peptides, polypeptides or proteins identified by such screens.

Abstract: A method of sorting items using multiple OCR attempts. A marking is read on the item with use of at least two or more of the following: a first algorithm with second settings; a second algorithm; and the first algorithm with second settings. The marking readings are compared to a database, and if the marking corresponds to data in the database, the data is selected. Readings may be performed simultaneously or consecutively. Also disclosed is a computer readable medium and system of one or more computers, and computer data signals embodied in a transmission medium to carry out the inventive methods, and a sorting system that carries out methods of the resent invention.

Abstract: A method of processing a plurality of mail items in an automated system without isolating each mail item on a scale. The method includes creation of a mail item record that identifies the item and includes the weight. Mail items may be weighed by determining a first scale weight reading, introducing a mail item onto the scale, determining the mail item weight at one or more times within a time window, and finding the difference between each consecutive scale weight. Differences between scale weight readings not equal to zero are outputted. All outputted scale weight readings are totaled to obtain the mail item weight. Further disclosed are a mail processing system and a method of ceasing mail processing when invalid weights are detected.

Abstract: A method of processing a plurality of mail items in an automated system without isolating each mail item on a scale. The method includes creation of a mail item record that identifies the item and includes the weight. Mail items may be weighed by determining a first scale weight reading, introducing a mail item onto the scale, determining the mail item weight at one or more times within a time window, and finding the difference between each consecutive scale weight. Differences between scale weight readings not equal to zero are outputted. All outputted scale weight readings are totaled to obtain the mail item weight. Further disclosed are a mail processing system and a method of ceasing mail processing when invalid weights are detected.

Abstract: An area of interest is scanned to produce pixels of the scanned area. The pixels are divided into a plurality of blocks. For each block, an orientation of a spanning line or a lack of orientation is determined. Contiguous ones of the blocks are clustered, when their orientation is within a certain tolerance level. Each cluster has a length and a width. The length is longer than the width. If the orientation of a cluster's block is perpendicular to the length of that cluster, that cluster is selected as a bar code candidate.

Abstract: An area of interest is scanned to produce pixels of the scanned area. The pixels are divided into a plurality of blocks. For each block, an orientation of a spanning line or a lack of orientation is determined. Contiguous ones of the blocks are clustered, when their orientation is within a certain tolerance level. Each cluster has a length and a width. The length is longer than the width. If the orientation of a cluster's block is perpendicular to the length of that cluster, that cluster is selected as a bar code candidate.

Abstract: A system for high speed acquisition and decoding of a barcode symbol locates potential barcode candidates within a scanned image and filters the candidates to eliminate invalid data. The system permits computational resources to be focused on decoding information most likely to be an actual barcode symbol. Once a potential barcode candidate has been located, the barcode symbol is processed to determine the barcode orientation and symbology. Each element of the barcode symbol is then located, even if all elements are not visible in the original image, and the barcode symbol is decoded in accordance with the specific symbology.

Abstract: A system for high speed acquisition and decoding of a barcode symbol locates potential barcode candidates within a scanned image and filters the candidates to eliminate invalid data. The system permits computational resources to be focused on decoding information most likely to be an actual barcode symbol. Once a potential barcode candidate has been located, the barcode symbol is processed to determine the barcode orientation and symbology. Each element of the barcode symbol is then located, even if all elements are not visible in the original image, and the barcode symbol is decoded in accordance with the specific symbology.

Abstract: A system for high speed acquisition and decoding of a barcode symbol locates potential barcode candidates within a scanned image and filters the candidates to eliminate invalid data. The system permits computational resources to be focused on decoding information most likely to be an actual barcode symbol. Once a potential barcode candidate has been located, the barcode symbol is processed to determine the barcode orientation and symbology. Each element of the barcode symbol is then located, even if all elements are not visible in the original image, and the barcode symbol is decoded in accordance with the specific symbology.

Abstract: An apparatus is provided for sorting a group of documents contained with an envelope into selected batches of documents. An envelope feeder feeds a group of envelopes containing documents onto a document transport. A document extractor positioned along the path of movement extracts the documents from the envelopes. A system controller identifies the documents extracted from each respective envelope as a single transaction along the path of movement. An orientation detector including a magnetic image reader and an optical image reader determines the orientation of selected documents along the path of movement. A document orientor changes the orientation of documents along the path of movement into a desired orientation. A document feeder is positioned downstream from the envelope feeder to selectively feed batch identification pieces into the path of movement.

Abstract: A camera mount is disclosed that includes a base clamp, with a pair of opposing adjustable gripping surfaces to engage an environmental support, such as a bookshelf or a tree branch. In the preferred embodiment, removably attached to the base, is an adaptor designed to receive the mast portions of the device. The adaptor has a plurality of apertures for receiving the first mast portion, thus increasing the possible angles at which the masts can be set relative to the base clamp. Additionally, in the preferred embodiment, each of the mast portions has an integral ball joint that allows the mast to have a "zig-zag" shape through various angles, if desired. This allows the field of view of the camera to avoid intervening obstacles, and aids in concealment, if desired. In a second embodiment of the invention, the adaptor and masts are replaced by a resiliently deformable "goose neck" arrangement.

Abstract: Disclosed are a transformed mammalian cell that produces biologically active Protein S, and a vector for effecting the transformation of the cell. produces biologically active human Protein S, and the vector used to effect the transgenesis of the cell. The vector disclosed includes DNA encoding mature human Protein S, under the transcriptional control of a eukaryotic metallothionein gene, and also includes the transforming region of the bovine papilloma virus genome, and a fragment of SV40 DNA.

Abstract: In a method of detecting blemishes in the proximity of the perimeter of a CCD image, pairs of adjacent pixels in the proximity of the perimeter are sequentially considered. For each pair of adjacent pixels, a plurality of pixels, in a blemish detection pixel pattern extending toward the center of the image are considered. The sum of the four outer pixels in the pixel pattern are compared to the sum of the inner pixels and the variance is compared to selected minimum and maximum differences. When the variance is outside either the minimum or the maximum differences a blemish has been detected. When the difference is within the two differences no blemish has been found. The blemish pattern is moved one pixel toward the center of the image and the process repeated. The difference comparison is repeated for a selected plurality of times and if desired the differences can be changed for some of the comparisons.

Abstract: Blemishes in the proximity of the perimeter of an image on a charge coupled device (CCD) are detected. The image pixels adjacent to the perimeter are sequentially detected and three consecutive pixels define a motion as either straight, clockwise or counterclockwise. The detection occurs in a clockwise direction and straight or clockwise motions are permitted. When two counterclockwise motions are detected, and a clockwise motion has not occurred between them, a blemish signal is provided.