Abstract: Disclosed herein are compositions and methods useful for the treatment or amelioration of various diseases, disorders, or conditions. Some aspects pertain to a composition comprising a testosterone source, an aromatase inhibitor, and an estriol source. Also presented herein is the surprising discovery that exposing a subject to the compositions disclosed herein can increase a subject's longevity, survival time, life span, and health span, as well as treat Alzheimer's disease.

Abstract: GPS map for commercial vehicle industry comprising of a navigation system and user interface to optimize needed navigation for a commercial vehicle based on physical criteria and content taking into consideration low bridge clearances, load limits, one-way road designations, left-hand and dangerous turn restrictions, and allowances pertaining to commercial vehicles. Based on the specified dimension and content of the vehicle, the system will display roads on the map with alerting color, texture to warn driver about roads where location of the vehicle is prohibited.

Abstract: Apparatus for determining a route for a road vehicle for a user comprising: a database of information pertaining to roads, the information comprising geographic data that includes map, location and configuration data for the roads, the information further comprising data indicative of a plurality of road characteristics or limits that pertain to the roads; a program having a first operation that compares a multiplicity of selected characteristics or limits of the road vehicle to the data indicative of the plurality of road characteristics or limits contained within the database and a second operation that computes one or more authorized road routes for the road vehicle; wherein the program includes instructions that compute one or more unauthorized road routes or portions of unauthorized road routes having road characteristics that are not complementary to or do not match the selected characteristics or limits of the road vehicle.