Patents by Inventor Edward George Bernstine

Edward George Bernstine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant heterodimeric human fertility hormones, and methods, cells, and vectors and DNA for the production thereof
    Patent number: 5767251
    Abstract: Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subunit being controlled by a separate promoter. Preferred human fertility hormones include hCG, hLH and hFSH.
    Type: Grant
    Filed: January 22, 1993
    Date of Patent: June 16, 1998
    Assignee: Genzyme Corporation
    Inventors: Vermuri B. Reddy, Nancy Hsiung, Anton K. Beck, Edward George Bernstine
  • DNA encoding the beta subunit of human follide stimulating hormone and expression vectors and cells containing same
    Patent number: 5639640
    Abstract: The correct sequence is disclosed for the beta subunit of human follicle stimulating hormone which, when present in a recombinant heterodimeric human fertility hormone allows the production of biologically active hormone. DNA coding for such beta subunit of human FSH may thus be prepared as well as expression vectors containing such DNA and cells transfected therewith.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 17, 1997
    Assignee: Genzyme Corporation
    Inventors: Vermuri B. Reddy, Nancy Hsiung, Anton K. Beck, Edward George Bernstine