Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: A communications system includes both cellular and land based telecommunications such as PSTN telephone, as well as cellular telephone. A subscriber may use prepaid cellular phone to make and receive calls via cellular network. A Mobile Switching Center (MSC) routes the subscriber's calls to and/or from wireline network for domestic connections and/or network for international connection. A Mobile Virtual Network Operator (MVNO) operates a prepaid vendor service control point (SCP), Prepaid Vendor Service Platform (PSP), and connected databases. A method of providing a universal communications account includes: providing at least one account to a customer, enabling use of the account for a first type of connection and a second type of connection; and debiting the account based at least in part on one of the first type of connection and the second type of connection.

Abstract: A communications system [100] includes both cellular and land based telecommunications such as PSTN telephone [115], [125], as well as cellular telephone [110]. A subcriber may use prepaid cellular phone [110] to make and receive calls via cellular network [120]. A Mobile Switching Center (MSC) [135] routes the subscriber's calls to and/or from wireline network [130] for domestic connections and/or network [145] for international connection. A Mobile Virtual Network Operator (MVNO) operates a prepaid vendor service control point (SCP) [140], Prepaid Vendor Service Platform (PSP) [150], and connected databases [155], [160], and [165]. A method of providing a universal communications account includes: providing at least one account to a customer, enabling use of the account for a first type of connection and a second type of connection; and debiting the account based at least i part on one of the first type of connection and the second type of connection.

Abstract: Disclosed herein are methods and systems for establishing a network-based system for purchase and sale of at least one of an option contract and a futures contract to acquire a travel-related item. The contract may be exercisable upon occurrence of a contingency and tradable in an online marketplace. In some instances, the contract may be exercisable upon future existence of the travel-related item, occurrence of a weather condition, or the outcome of a contest, any of which may be uncertain at the time of the purchase and sale of the contract.

Abstract: A system for allowing a remote user to purchase and trade, over a distributed computer network (e.g., the Internet), an option for a ticket and/or accommodations for a “contingent event,” i.e., an event which is certain to occur but for which the participants, content and/or location(s) are not predetermined. For instance, the subject system can be used to sell and trade options for the purchase of tickets to such contingent events such as playoff games on the basis of what teams qualify.

Abstract: A system for allowing a remote user to purchase and trade, over a distributed computer network (e.g., the Internet), an option for a ticket and/or accommodations for a “contingent event,” i.e., an event which is certain to occur but for which the participants, content and/or location(s) are not predetermined. For instance, the subject system can be used to sell and trade options for the purchase of tickets to such contingent events such as playoff games on the basis of what teams qualify.

Abstract: A system for allowing a remote user to purchase, over a distributed computer network (e.g., the Internet), an option for a ticket and/or accommodations for a “contingent event,”i.e., an event which is certain to occur but for which the participants, content and/or location(s) are not predetermined. For instance, the subject system can be used to sell options for the purchase of tickets to contingent events such as playoff games on the basis of what individuals qualify for the game.

Abstract: Methods and systems of establishing a network-based system for purchase and sale of at least one of an option contract and a futures contract to acquire an item or to attend an event, wherein the contract is exercisable upon the occurrence of a contingency. The contingency may relate to the presence of a particular team in a game and the location of the game. In some instances, the contingency may relate to the position of a participant in the event in the standings at a time proximate to the occurrence of the event.

Abstract: Disclosed herein is a system for allowing a remote user to purchase, over a distributed computer network (e.g., the Internet), an option for a ticket and/or accommodations for a “contingent event”, e.g., an event which is certain to occur but for which the participants, content and/or location(s) are not predetermined. For instance, the subject system can be used to sell options for the purchase of tickets to such contingent events such as playoff games on the basis of what teams qualify, or all-star game.

Abstract: A mobile data processing and communications system having a keyboard converter mounted in a vehicle and detachably interconnected to a self-contained removable hand-held portable computer. The hand-held portable computer includes a microprocessor with an interactive display and an integral internal RF antenna to enable the user to perform data processing and communications functions outside the vehicle. When the hand-held portable computer interfaces with the keyboard converter, the user may enter data through the keyboard converter and communicate via an external RF antenna attached to the vehicle.