Patents by Inventor Edward K. F. Lee
Edward K. F. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240033530Abstract: In accordance with the present invention, various embodiments of neurostimulators and stimulation systems are disclosed that provide different shapes and patterns of stimulus pulses and trains of pulses with fixed and no fixed frequencies. The neurostimulator can be configured to provide high frequency stimulation and also be implantable in the head or neck regions in order to stimulate nerves and nerve ganglions in the head and neck regions and also stimulate the brain.Type: ApplicationFiled: October 4, 2023Publication date: February 1, 2024Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Brian R. Dearden, Harshit Suri, Edward K. F. Lee
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Patent number: 11338144Abstract: A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.Type: GrantFiled: February 14, 2020Date of Patent: May 24, 2022Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K. F. Lee
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Patent number: 10925489Abstract: A medical system and method of communicating between a telemetry controller and medical devices is provided. Coupling coefficients between a primary coil of the telemetry controller and secondary coils of the medical devices differ from each other. A primary carrier signal is applied to the primary coil, thereby respectively inducing secondary carrier signals on the secondary coils. An amplitude of the secondary carrier signal is measured on each of the secondary coils. The envelope of each secondary carrier signal is modulated in accordance with data, thereby inducing modulation of the envelope of the primary carrier signal for the implanted medical devices. The secondary carrier signal envelopes are modulated based on the measured amplitudes of the respective secondary carrier signals.Type: GrantFiled: September 24, 2019Date of Patent: February 23, 2021Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Edward K. F. Lee, Harshit R. Suri
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Publication number: 20200269054Abstract: In accordance with the present invention, various embodiments of neurostimulators and stimulation systems are disclosed that provide different shapes and patterns of stimulus pulses and trains of pulses with fixed and no fixed frequencies. The neurostimulator can be configured to provide high frequency stimulation and also be implantable in the head or neck regions in order to stimulate nerves and nerve ganglions in the head and neck regions and also stimulate the brain.Type: ApplicationFiled: May 4, 2020Publication date: August 27, 2020Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Brian R. Dearden, Harshit Suri, Edward K. F. Lee
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Publication number: 20200179702Abstract: A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.Type: ApplicationFiled: February 14, 2020Publication date: June 11, 2020Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: EDWARD K.F. LEE
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Patent number: 10639480Abstract: In accordance with the present invention, various embodiments of neurostimulators and stimulation systems are disclosed that provide different shapes and patterns of stimulus pulses and trains of pulses with fixed and no fixed frequencies. The neurostimulator can be configured to provide high frequency stimulation and also be implantable in the head or neck regions in order to stimulate nerves and nerve ganglions in the head and neck regions and also stimulate the brain.Type: GrantFiled: December 21, 2017Date of Patent: May 5, 2020Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Brian R. Dearden, Harshit Suri, Edward K. F. Lee
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Patent number: 10603495Abstract: A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.Type: GrantFiled: May 15, 2018Date of Patent: March 31, 2020Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K.F. Lee
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Patent number: 10568513Abstract: A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).Type: GrantFiled: February 28, 2018Date of Patent: February 25, 2020Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Edward K. F. Lee, Harshit R. Suri
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Patent number: 10537246Abstract: A medical system and method of communicating between a telemetry controller and medical devices is provided. Coupling coefficients between a primary coil of the telemetry controller and secondary coils of the medical devices differ from each other. A primary carrier signal is applied to the primary coil, thereby respectively inducing secondary carrier signals on the secondary coils. An amplitude of the secondary carrier signal is measured on each of the secondary coils. The envelope of each secondary carrier signal is modulated in accordance with data, thereby inducing modulation of the envelope of the primary carrier signal for the implanted medical devices. The secondary carrier signal envelopes are modulated based on the measured amplitudes of the respective secondary carrier signals.Type: GrantFiled: February 7, 2018Date of Patent: January 21, 2020Assignee: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Edward K. F. Lee, Harshit R. Suri
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Publication number: 20200015682Abstract: A medical system and method of communicating between a telemetry controller and medical devices is provided. Coupling coefficients between a primary coil of the telemetry controller and secondary coils of the medical devices differ from each other. A primary carrier signal is applied to the primary coil, thereby respectively inducing secondary carrier signals on the secondary coils. An amplitude of the secondary carrier signal is measured on each of the secondary coils. The envelope of each secondary carrier signal is modulated in accordance with data, thereby inducing modulation of the envelope of the primary carrier signal for the implanted medical devices. The secondary carrier signal envelopes are modulated based on the measured amplitudes of the respective secondary carrier signals.Type: ApplicationFiled: September 24, 2019Publication date: January 16, 2020Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: EDWARD K.F. LEE, HARSHIT R. SURI
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Publication number: 20190015664Abstract: A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.Type: ApplicationFiled: May 15, 2018Publication date: January 17, 2019Applicant: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: EDWARD K.F. LEE
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Publication number: 20180256030Abstract: A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).Type: ApplicationFiled: February 28, 2018Publication date: September 13, 2018Applicant: The Alfred E. Mann Foundation for Scientific ResearchInventors: EDWARD K. F. LEE, HARSHIT R. SURI
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Publication number: 20180220891Abstract: A medical system and method of communicating between a telemetry controller and medical devices is provided. Coupling coefficients between a primary coil of the telemetry controller and secondary coils of the medical devices differ from each other. A primary carrier signal is applied to the primary coil, thereby respectively inducing secondary carrier signals on the secondary coils. An amplitude of the secondary carrier signal is measured on each of the secondary coils. The envelope of each secondary carrier signal is modulated in accordance with data, thereby inducing modulation of the envelope of the primary carrier signal for the implanted medical devices. The secondary carrier signal envelopes are modulated based on the measured amplitudes of the respective secondary carrier signals.Type: ApplicationFiled: February 7, 2018Publication date: August 9, 2018Applicant: The Alfred E. Mann Foundation for Scientific Resea rchInventors: EDWARD K. F. LEE, HARSHIT R. SURI
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Patent number: 10033296Abstract: Systems and methods for rectifying and regulating an input voltage are disclosed. A biasing circuit is configured to generate a biasing voltage greater than the maximum value of the input voltage minus a forward bias voltage of a p-n junction diode and apply the biasing voltage to the body terminal of a MOSFET. The biasing circuit may generate the biasing voltage by rectifying the input voltage. A control circuit is configured to generate a gate voltage based on the rectified and regulated output voltage and apply the gate voltage to the gate terminal of the MOSFET.Type: GrantFiled: September 1, 2016Date of Patent: July 24, 2018Assignee: The Alfred E. Mann Foundation for Scientific ResearchInventor: Edward K. F. Lee
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Publication number: 20180178015Abstract: In accordance with the present invention, various embodiments of neurostimulators and stimulation systems are disclosed that provide different shapes and patterns of stimulus pulses and trains of pulses with fixed and no fixed frequencies. The neurostimulator can be configured to provide high frequency stimulation and also be implantable in the head or neck regions in order to stimulate nerves and nerve ganglions in the head and neck regions and also stimulate the brain.Type: ApplicationFiled: December 21, 2017Publication date: June 28, 2018Applicant: THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventors: Brian R. Dearden, Harshit Suri, Edward K. F. Lee
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Patent number: 9981130Abstract: A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.Type: GrantFiled: September 12, 2016Date of Patent: May 29, 2018Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K. F. Lee
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Patent number: 9837831Abstract: A feedback controlled coil driver with ASK modulation is disclosed. A class E coil driver drives an LC circuit to generate a magnetic signal via the inductor. A modulation capacitor is coupled to the LC circuit to modulate the coil driver signal. The voltage across the coil driver switch is sampled. The difference between the sampled voltage and a reference voltage is integrated and compared to a ramp voltage to obtain an optimal on time for the coil driver switch such that coil current is maximized.Type: GrantFiled: April 28, 2015Date of Patent: December 5, 2017Assignee: The Alfred E. Mann Foundation For Scientific ResearchInventor: Edward K. F. Lee
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Patent number: 9728981Abstract: A fully integrated feedback controlled coil driver is disclosed for inductive power transfer to electronic devices. For efficient power transfer, a voltage across a switch that switchably couples the coil between a DC input power source and ground is sampled and compared with a preselected reference voltage to generate an error voltage. The error voltage is integrated over time and compared to a voltage ramp. The value of the integrated error voltage relative to the voltage ramp is used to obtain an optimal on time for the switch such that coil current is maximized for a given DC input power. The coil driver can also provide ASK modulation on the coil current by changing the size of the switch according to input data.Type: GrantFiled: February 25, 2015Date of Patent: August 8, 2017Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K. F. Lee
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Patent number: 9715243Abstract: A timing controlled converter and method for converting a time varying input signal to a regulated DC output voltage for application to a load circuit. A feedback loop is employed as a control means for switchably coupling the time varying input signal to the load circuit for controlled periods of time in a manner so as to provide an average load voltage equal to a reference voltage. The duration of the controlled periods of time is a function of: the difference between the time varying input signal and the output voltage; and the integral of the difference between the output voltage and the reference voltage.Type: GrantFiled: January 19, 2015Date of Patent: July 25, 2017Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K. F. Lee
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Patent number: 9682237Abstract: A successive approximation ADC made of a low voltage configurable differential amplifier and low voltage logic circuits which can convert a high voltage analog input to a digital equivalent. The differential amplifier can be configured as either an op amp or a comparator depending upon the mode of operation. An input capacitor C1 is switchably coupled to an electrode selected for voltage sampling. A switched capacitor array C2 is coupled across the differential amplifier input and output. A SAR coupled to the switched capacitor array provides a digital output corresponding to the sampled analog voltage. During a sampling interval and a charge transfer interval, the differential amplifier is configured as an op amp. During the transfer interval, the voltage on the input capacitor multiplied by the ratio C1/C2 is transferred to the switched capacitor array. During an analog to digital conversion interval, the ADC converts the analog voltage to an equivalent digital output.Type: GrantFiled: April 22, 2015Date of Patent: June 20, 2017Assignee: ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCHInventor: Edward K. F. Lee