Abstract: The present invention relates to a multipurpose drill system, the multipurpose drill system comprising: a drilling rig adapted to drive a drilling assembly; and two or more power sources, wherein at least one of the two or more power sources is a high pressure power source, wherein the drilling assembly is adapted to be in communication with either or both of the two or more power sources.

Abstract: The updating of a definition layer or schema for a large distributed database can be accomplished using a plurality of data store tiers. A distributed database can be made up of many individual data stores, and these data stores can be allocated across a set of tiers based on business logic or other allocation criteria. The update can be applied sequentially to the individual tiers, such that only data stores for a single tier are being updated at any given time. This can help to minimize downtime for the database as a whole, and can help to minimize problems that may result from an unsuccessful update. Such an approach can also allow for simplified error detection and rollback, as well as providing control over a rate at which the update is applied to the various data stores of the distributed database.

Abstract: Among other things, embodiments of the present disclosure provide systems and methods for modifying avatar components of avatar datasets for multiple users, generating avatars based on the datasets, and displaying multiple avatars on a display screen of a graphical user interface.

Abstract: Oncolytic viral vectors that incorporate one or more of the following features: viral replication restriction by insertion of microRNA (miRNA) target sequences into the viral genome; disruption of oncogenic miRNA function; cancer microenvironment remodeling; and cancer cell targeting by incorporation of protease-activated antibodies into the viral particle. Such viral vectors can be used for the treatment and prevention of cancer.

Abstract: Oncolytic viral vectors that incorporate one or more of the following features: viral replication restriction by insertion of microRNA (miRNA) target sequences into the viral genome; disruption of oncogenic miRNA function; cancer microenvironment remodeling; and cancer cell targeting by incorporation of protease-activated antibodies into the viral particle. Such viral vectors can be used for the treatment and prevention of cancer.

Abstract: Various embodiments include methods and systems to measure and calibrate an optical particle spectrometer for reporting mass concentration. In one embodiment, an optical particle spectrometer is used to measure a concentration of particulate matter in a sampled particle-laden airstream. A particle diverter, in fluid communication with the spectrometer, diverts at least a portion of the particle-laden airstream at predetermined intervals. In one example, a mass filter receives the portion of the particle-laden airstream and filters a fraction of the particles within the airstream that are above a predetermined particle size. A mass sensor measures a mass of the fraction of the particles received from the mass filter or from the particle diverter and uses a calibration communication loop to provide the measured mass to the spectrometer to apply a correction factor to report mass concentration from the optical particle spectrometer. Other methods and systems are disclosed.

Abstract: A key distribution host determines a trust level of a user authentication server, wherein the trust level is based, at least in part, on one or more attributes of the user authentication server and provides one or more authentication keys to the user authentication server only if the trust level of the user authentication server is above a threshold value.

Abstract: A policy management service receives a request to associate a version of a computing resource policy as a default version of the policy. In response to the request, the service identifies, from a policy database, an entry for the default version of the policy. The service updates the entry in order to associate the version specified in the request as the default version of the policy. This results in the version of the policy becoming applicable to control access to the computing resources associated with principals associated with the default version of the policy.

Abstract: The present disclosure relates to polynucleotides comprising a nucleic acid sequence encoding a replication competent viral genome, wherein the polynucleotide is capable of producing a replication competent virus when introduced into a cell by a non-viral delivery vehicle. The present disclosure further relates to the encapsulation of the polynucleotides and the use of the polynucleotides and/or particles for the treatment and prevention of cancer.

Abstract: A consistent view of associations between independently replicated data objects may be provided. Data objects may be stored in separate data stores. Copies of the data stores may also store the data objects. The copies of the data stores may independently receive the data objects to be stored as part of independently replicating data stores to one or more copies of the data stores. An association can be created between objects in the different data store. If when the association is created it is determined that a referenced object is not yet stored in a copy of a data store, then both the association and the referenced object may be stored in the same data store so that the association and the referenced object are replicated together to a copy of the same data store.

Abstract: The present invention relates to a drill bit replacement apparatus for replacing a drill bit on a drilling tool, the apparatus comprising: a drill bit holder comprising one or more drill bit receptacles, each drill bit receptacle adapted to receive at least one drill bit; and a positioning means adapted to move the drill bit holder between at least one storage position and one or more replacement positions, wherein each replacement position aligns at least one drill bit receptacle with the drilling tool.

Abstract: A security token service receives a request for a token. The request indicates a set of access control policies that define a set of permissions for access to a resource. The security token service generates the token to comprise a set of identifiers of the set of access control policies. The security token service provides the token in response to the request to enable the token to be used to access the resource in accordance with the set of access control policies.

Abstract: The present invention relates to a multipurpose drill system, the multipurpose drill system comprising: a drilling rig adapted to drive a drilling assembly; and two or more power sources, wherein at least one of the two or more power sources is a high pressure power source, wherein the drilling assembly is adapted to be in communication with either or both of the two or more power sources.

Abstract: A key distribution host determines a trust level of a user authentication server, wherein the trust level is based, at least in part, on one or more attributes of the user authentication server and provides one or more authentication keys to the user authentication server only if the trust level of the user authentication server is above a threshold value.

Abstract: The present disclosure relates to recombinant viral vectors for the treatment and prevention of cancer. Oncolytic viral vectors incorporate one or more of the following features: viral replication restriction by insertion of microRNA (miRNA) target sequences into the viral genome; disruption of oncogenic miRNA function; cancer microenvironment remodeling; and cancer cell targeting by incorporation of protease-activated antibodies into the viral particle.

Abstract: Various embodiments include methods and systems to measure and calibrate an optical particle spectrometer for reporting mass concentration. In one embodiment, an optical particle spectrometer is used to measure a concentration of particulate matter in a sampled particle-laden airstream. A particle diverter, in fluid communication with the spectrometer, diverts at least a portion of the particle-laden airstream at predetermined intervals. In one example, a mass filter receives the portion of the particle-laden airstream and filters a fraction of the particles within the airstream that are above a predetermined particle size. A mass sensor measures a mass of the fraction of the particles received from the mass filter or from the particle diverter and uses a calibration communication loop to provide the measured mass to the spectrometer to apply a correction factor to report mass concentration from the optical particle spectrometer. Other methods and systems are disclosed.

Abstract: A fishing lure imitating a bird has a body having a central long axis with equal longitudinal buoyancy, a set of two simulated eyes, groups of buoyant flexible strands each joined at one end to the body simulating extended bird wings, and a hook element disposed longitudinally through the cylindrical body with a shank extending rearward in the body along the long axis, the shank exiting the body in an upward-facing lengthwise recess, then bending forward to present a hook point.

Abstract: Compositions and methods for changing the color of non-wood substrates. A one step method uses a solution of a water soluble pigment or dye and a metal salt. The non-toxic solution can be sprayed on a primed or unprimed substrate without wiping. The method can produce an even color on a smooth substrate, or a simulated woodgrain pattern or color on a textured substrate. The composition and method can be used on substrates as varied as fiberboard, fiberglass, steel, vinyl, plastics, metals, concrete, brick, stone, and stucco. The composition can include a resin which is emulsified when added and subsequently demulsifies. A two step method includes the additional step of applying a gall ink to the substrate. The compositions can be distributed as kits containing multiple packages of dry or concentrated ingredients, which make the final composition(s) when hydrated.

Abstract: A fishing lure imitating a bird has a body having a central long axis with equal longitudinal buoyancy, a set of two simulated eyes, groups of buoyant flexible strands each joined at one end to the body simulating extended bird wings, and a hook element disposed longitudinally through the cylindrical body with a shank extending rearward in the body along the long axis, the shank exiting the body in an upward-facing lengthwise recess, then bending forward to present a hook point.

Abstract: A fishing lure imitating a winged prey has a cylindrical body having a conical front end and a rounded rear end, one or more first groupings of flexible strands, the multi-strand groupings disposed transversely through walls of the cylindrical body and secured thereto, the free ends of each multi-strand group protruding substantially orthogonally from the cylindrical body on opposite sides to imitate bird wings, one or more second groupings of flexible strands disposed through a rear wall of the cylindrical body and secured thereto, the free end of each multi-strand grouping protruding from the rear of the cylindrical body to imitate a bird tail, and a hook assembly disposed longitudinally through the cylindrical body, the hook assembly including a shank having a closed front eyelet and a partially open rear eyelet, and a hook attached to the shank at the rear eyelet.