Patents by Inventor Edward M. Cohen

Edward M. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • pH-Mediated drug delivery system
    Patent number: 4756710
    Abstract: A method and device for delivering acidic or basic drugs in a controlled delivery system is described.
    Type: Grant
    Filed: March 7, 1986
    Date of Patent: July 12, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Joseph V. Bondi, Alice E. Loper, Edward M. Cohen
  • Transdermal system for timolol
    Patent number: 4752478
    Abstract: A method and device for administering timolol for an extended period is described. By the method and device, transdermal application of timolol may be accomplished with substantially no irritation to the skin.
    Type: Grant
    Filed: December 17, 1984
    Date of Patent: June 21, 1988
    Assignee: Merck & Co., Inc.
    Inventors: Joseph V. Bondi, Alice E. Loper, Edward M. Cohen
  • Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)- 3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid
    Patent number: 4751220
    Abstract: In accordance with the present invention an orally active monosulfactam antibiotics having a crystalline structure and thereby improved stability are disclosed. The antibiotics comprise the dierythromycin (M.sup..sym.=erythromycin.H.sup..sym.) salt or the dicholine (M.sup..sym. =HOCH.sub.2 CH.sub.2 N.sup..sym. (CH.sub.3).sub.3) salt of the acid (M.sup..sym. =H.sup..sym.) having the formula ##STR1## that is, [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3- azetidinyl]-amino]-2-oxoethylidene]amino]oxy]acetic acid.
    Type: Grant
    Filed: December 19, 1986
    Date of Patent: June 14, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: W. Lawrence Parker, Edward M. Cohen, William H. Koster
  • Solid state ophthalmic medication
    Patent number: 4179497
    Abstract: Solid unit dosage medicaments which are suitable for use in animals and humans are prepared with hydroxypropyl cellulose as the primary formulating excipient. These medicaments are particularly suitable for ophthalmic use since they are slowly but completely water soluble when they are inserted in the cul-de-sac of the eye and thus provide for a convenient means of prolonged treatment of the eye with concomitant reduced dosing frequency.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: December 18, 1979
    Assignee: Merck & Co., Inc.
    Inventors: Edward M. Cohen, Wayne M. Grim, Richard J. Harwood, Gunvant N. Mehta
  • Process for preparing a novel benzylamine hydrate
    Patent number: 4046804
    Abstract: .alpha.,.alpha.-Dimethyl-4-(.alpha.,.alpha.,.beta.,.beta.-tetrafluorophenet hyl)benzylamine isethionate monohydrate and processes for its preparation are disclosed.
    Type: Grant
    Filed: October 1, 1976
    Date of Patent: September 6, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Edward M. Cohen, Earl R. Oberholtzer