Patents by Inventor Edward M. Matelan

Edward M. Matelan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indazoles
    Patent number: 7592363
    Abstract: This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.
    Type: Grant
    Filed: August 1, 2005
    Date of Patent: September 22, 2009
    Assignee: Wyeth
    Inventors: Robert J. Steffan, Edward M. Matelan, Stephen M. Bowen, John W. Ullrich, Jay E. Wrobel, Edouard Zamaratski, Lars Kruger, Annabel L. Olsen Hedemyr, Aiping Cheng, Tomas Hansson, Rayomand J. Unwalla, Christopher P. Miller, Patrik P. Rhönnstad
  • Substituted 4-(indazol-3-yl)phenols
    Patent number: 7241791
    Abstract: This invention provides compound of formulae I or II having the structure wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined in the specification or a pharmaceutically acceptable salt thereof which are useful for the treatment of the inflammatory component of diseases and are particularly useful in treating atherosclerosis, myocardial infarction, congestive heart failure, inflammatory bowel disease, arthritis, type II diabetes, and autoimmune diseases such as multiple sclerosis and rheumatiod arthritis.
    Type: Grant
    Filed: September 24, 2003
    Date of Patent: July 10, 2007
    Assignee: Wyeth
    Inventors: Robert J. Steffan, Edward M. Matelan, Mark A. Ashwell, William R. Solvibile
  • Substituted 4-(indazol-3-yl)phenols
    Publication number: 20040167127
    Abstract: This invention provides compound of formulae I or II having the structure 1
    Type: Application
    Filed: September 24, 2003
    Publication date: August 26, 2004
    Applicant: Wyeth
    Inventors: Robert J. Steffan, Edward M. Matelan, Mark A. Ashwell, William R. Solvibile
  • Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists
    Publication number: 20020037907
    Abstract: This invention provides compounds of Formula I having the structure 1
    Type: Application
    Filed: July 12, 2001
    Publication date: March 28, 2002
    Applicant: American Home Products Corporation
    Inventors: Robert J. Steffan, Mark A. Ashwell, Jeffrey C. Pelletier, William R. Solvibile, Edward M. Matelan
  • Substituted hydroxy-anilino derivatives of cyclobutene-3,4-diones
    Patent number: 5840764
    Abstract: The compound of the formula: ##STR1## wherein R.sup.1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl, or polyfluoroalkyl; and one of R.sup.2, R.sup.3 and R.sup.4 is hydroxyl and the other two are, independently, H, CN, halogen, alkyl or hydroxyl; or a pharmaceutically acceptable salt thereof, is useful as a smooth muscle relaxant.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: November 24, 1998
    Assignee: American Home Products Corporation
    Inventors: Dominick A. Quagliato, Edward M. Matelan, Madelene M. Antane