Patents by Inventor Edward M. Trujillo

Edward M. Trujillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Culture method for multilayer growth of anchorage-dependent cells
    Patent number: 5702949
    Abstract: Anchorage-dependent cells are grown on a novel substratum which is believed to increase the oxygenation of the cells and reduce the formation of free-radicals. The substratum consists of a perfluorocarbon reservoir which is coated with a layer of protein (e.g.,collagen or gelatin) which has been perfluoroalkylated. The perfluoroalkylated protein forms a very stable surface to which anchorage-dependent cells can attach and grow. Using this system, mammalian cell cultures have been grown to densities exceeding 10.sup.7 cells/cm.sup.2. The increased density is attributed to the formation of multiple cell layers which resemble tissue-like structures.
    Type: Grant
    Filed: June 19, 1996
    Date of Patent: December 30, 1997
    Assignee: University of Utah Research Foundation
    Inventors: Edward M. Trujillo, Catherine Rappaport