Patents by Inventor Edward Marshall Alderman

Edward Marshall Alderman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and systems for the rapid characterization of functional biological molecules
    Patent number: 9594081
    Abstract: In one non-limiting aspect, the invention provides a method for detecting the quality of a biological molecule comprising forming a first mixture of ingredients comprising: (i) a first binding agent that specifically binds to a tag, wherein the first binding agent is attached to a solid support; (ii) a decoy comprising a first portion comprising the tag attached to a second portion comprising an anchor; (iii) a sensor attached to a second binding agent that specifically binds to the anchor; and (iv) a sample suspected of containing a high quality biological molecule comprising a tag, wherein the tag of the high quality biological molecule is accessible; allowing interaction of the ingredients such that the sensor provides an output signal.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: March 14, 2017
    Assignee: ProterixBio, Inc.
    Inventors: Edward Marshall Alderman, Brett Peter Masters, Michael Francis Miller, William Matthew Dickerson
  • Methods and Kits for Analyzing Biomarkers in a Signal Transduction Pathway
    Publication number: 20150057180
    Abstract: Provided are methods and kits for analyzing biomarkers in one or more signal transduction pathways in a cell. In some embodiments, the methods and kits of the invention permit simultaneous analysis of more than one biomarker and/or more than one signal transduction pathway. In some embodiments, the invention provides methods for detecting whether a cell treated with an agent targeting a targeted biomarker is responding to the agent, or whether the cell is developing resistance to the agent. In some embodiments, the invention provides methods for determining which biomarker to target in a diseased or damaged cell, or which pathway an agent is targeting in an agent-treated cell. The invention provides kits for carrying out the described methods.
    Type: Application
    Filed: September 5, 2014
    Publication date: February 26, 2015
    Inventors: Edward Marshall Alderman, Matthew William Dickerson, Lee Anne Beausang, Brett Peter Masters, Martin Latterich
  • Methods and Systems For the Rapid Characterization of Functional Biological Molecules
    Publication number: 20150031047
    Abstract: In one non-limiting aspect, the invention provides a method for detecting the quality of a biological molecule comprising forming a first mixture of ingredients comprising: (i) a first binding agent that specifically binds to a tag, wherein the first binding agent is attached to a solid support; (ii) a decoy comprising a first portion comprising the tag attached to a second portion comprising an anchor; (iii) a sensor attached to a second binding agent that specifically binds to the anchor; and (iv) a sample suspected of containing a high quality biological molecule comprising a tag, wherein the tag of the high quality biological molecule is accessible; allowing interaction of the ingredients such that the sensor provides an output signal
    Type: Application
    Filed: June 20, 2012
    Publication date: January 29, 2015
    Applicant: BioScale, Inc.
    Inventors: Edward Marshall Alderman, Brett Peter Masters, Michael Francis Miller, William Matthew Dickerson