Patents by Inventor Edward Sinclair

Edward Sinclair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108645
    Abstract: The present invention relates to a method of treating or preventing DNA damage in a cell or cellular senescence of a cell or induction of the senescence associated secretory phenotype (SASP) in a cell, or for treating or preventing the effects of aging, or for preventing or treating cellular senescence and/or induction of SASP associated with high caloric intake or obesity, or for reducing the side effects of chemotherapy, radiotherapy, corticoid treatment, anti-retroviral treatment, or PPAR? agonist treatment comprising administering an effective amount of an NAD+ agonist.
    Type: Application
    Filed: May 5, 2023
    Publication date: April 4, 2024
    Inventors: Lindsay Edward WU, David Andrew SINCLAIR
  • Publication number: 20150168277
    Abstract: Disclosed herein are apparatuses and methods handling a portion of a tissue sample when sectioned by a microtome. The apparatuses include a container, a tissue sample holder in the container, and one or more outlets configured to allow flow of a fluid from the container. the flow through the outlet causes a portion of the tissue sample sectioned by a microtome to move into the outlet. The methods include sectioning one or more portions of a tissue sample, and flowing a fluid past the tissue sample to cause the one or more portions of the tissue sample to move away from the tissue sample and toward at least one fluid outlet.
    Type: Application
    Filed: February 25, 2015
    Publication date: June 18, 2015
    Inventors: Sanjay Shivayogi Magavi, Jack Barger, Michael Paul Emery, James Edward Sinclair, Jorge Arturo Ayala
  • Patent number: 8967024
    Abstract: Apparatuses and methods for handling a portion of a tissue sample when sectioned by a microtome. The apparatuses include a container, a tissue sample holder in the container, and one or more outlets configured to allow flow of a fluid from the container. The flow through the outlet causes a portion of the tissue sample sectioned by a microtome to move into the outlet. The methods include sectioning one or more portions of a tissue sample, and flowing a fluid past the tissue sample to cause the one or more portions of the tissue sample to move away from the tissue sample and toward at least one fluid outlet.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: March 3, 2015
    Assignee: Vertex Pharmaceuticals, Inc.
    Inventors: Sanjay Shivayogi Magavi, Jack Barger, Michael Paul Emery, James Edward Sinclair, Jorge Arturo Ayala
  • Patent number: 8783339
    Abstract: Apparatuses, systems, and methods in accordance with the present disclosure are disclosed herein. The system includes a gripping tool operatively connected to and suspended from the top drive assembly, in which the gripping tool includes an axis defined therethrough and a gripping member, and an adaptor apparatus having a first end and a second end. The at least one gripping member engages the adaptor apparatus, and the second end includes a connection member to connect with the tubular member.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: July 22, 2014
    Assignee: Frank's International, Inc.
    Inventors: Edward Sinclair, Guy Hustinx, Patrick Neil Sibille
  • Publication number: 20140046182
    Abstract: Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.
    Type: Application
    Filed: September 6, 2013
    Publication date: February 13, 2014
    Inventors: Viviane Connor, Betsy Swann, Edward Sinclair
  • Patent number: 8551001
    Abstract: Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: October 8, 2013
    Assignee: Conceptus, Inc.
    Inventors: Viviane Connor, Edward Sinclair, Betsy Swann
  • Publication number: 20130019725
    Abstract: Disclosed herein are apparatuses and methods handling a portion of a tissue sample when sectioned by a microtome. The apparatuses include a container, a tissue sample holder in the container, and one or more outlets configured to allow flow of a fluid from the container. the flow through the outlet causes a portion of the tissue sample sectioned by a microtome to move into the outlet. The methods include sectioning one or more portions of a tissue sample, and flowing a fluid past the tissue sample to cause the one or more portions of the tissue sample to move away from the tissue sample and toward at least one fluid outlet.
    Type: Application
    Filed: July 20, 2011
    Publication date: January 24, 2013
    Applicant: Vertex Pharmaceuticals, Inc.
    Inventors: Sanjay Shivayogi Magavi, Jack Barger, Michael Paul Emery, James Edward Sinclair, Jorge Arturo Ayala
  • Publication number: 20120190980
    Abstract: Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.
    Type: Application
    Filed: February 16, 2012
    Publication date: July 26, 2012
    Inventors: Viviane Connor, Edward Sinclair, Betsy Swann
  • Patent number: 8123693
    Abstract: Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.
    Type: Grant
    Filed: June 20, 2006
    Date of Patent: February 28, 2012
    Assignee: Conceptus, Inc.
    Inventors: Viviane Connor, Edward Sinclair, Betsy Swann
  • Publication number: 20110174542
    Abstract: Apparatuses, systems, and methods in accordance with the present disclosure are disclosed herein. The system includes a gripping tool operatively connected to and suspended from the top drive assembly, in which the gripping tool includes an axis defined therethrough and a gripping member, and an adaptor apparatus having a first end and a second end. The at least one gripping member engages the adaptor apparatus, and the second end includes a connection member to connect with the tubular member.
    Type: Application
    Filed: January 14, 2011
    Publication date: July 21, 2011
    Applicant: FRANK'S INTERNATIONAL, INC.
    Inventors: Edward Sinclair, Guy Hustinx, Patrick Neil Sibille
  • Publication number: 20110137150
    Abstract: Embodiments of the present invention describe methods of determining the occlusion of body lumens and apparatuses for doing so. In one particular embodiment, the occlusion of the fallopian tubes by an intrafallopian contraceptive device may be confirmed by contrast enhanced ultrasonography (also known as stimulated acoustic emission hysterosalpingo-contrast sonography). In these embodiments a contrast agent containing microbubbles is used.
    Type: Application
    Filed: June 20, 2006
    Publication date: June 9, 2011
    Inventors: Viviane Connor, Edward Sinclair, Betsy Swann
  • Patent number: 7337853
    Abstract: Method and apparatus for installing control lines and pipe into a well. The pipe-holding spider that is normally mounted on the rig floor is supportably retained in a vertically movable retainer. The retainer is adapted for controllably elevating the spider above the rig floor when the pipe slips within the spider are not engaged with the outer surface of the pipe string, thereby providing personnel access to a portion of the length of the pipe string below the elevated spider and above the rig floor. Personnel are provided with access to the pipe string for applying a fastener to secure the control line to the pipe string. The control line is supplied from above the spider and is positioned by a control line guide supported on the spider or retainer to pass through the spider outside the path of pipe gripping members within the spider.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: March 4, 2008
    Assignee: Frank's International, Inc.
    Inventors: Jean Buytaert, Luciano Spadoni, Edward Sinclair, Brian David Begnaud, Charles Michael Webre
  • Publication number: 20060108122
    Abstract: Method and apparatus for installing control lines and pipe into a well. The pipe-holding spider that is normally mounted on the rig floor is supportably retained in a vertically movable retainer. The retainer is adapted for controllably elevating the spider above the rig floor when the pipe slips within the spider are not engaged with the outer surface of the pipe string, thereby providing personnel access to a portion of the length of the pipe string below the elevated spider and above the rig floor. Personnel are provided with access to the pipe string for applying a fastener to secure the control line to the pipe string. The control line is supplied from above the spider and is positioned by a control line guide supported on the spider or retainer to pass through the spider outside the path of pipe gripping members within the spider.
    Type: Application
    Filed: January 10, 2006
    Publication date: May 25, 2006
    Inventors: Jean Buytaert, Luciano Spadoni, Edward Sinclair, Brian Begnaud, Charles Webre
  • Publication number: 20050183862
    Abstract: A method and apparatus are provided for installing control lines and pipe into a well. The pipe-holding spider that is normally mounted on the rig floor is supportably retained in a vertically movable retainer. The retainer is adapted for controllably elevating the spider above the rig floor when the pipe slips within the spider are not engaged with the outer surface of the pipe string, thereby providing personnel access to a portion of the length of the pipe string below the elevated spider and above the rig floor. Personnel are provided with access to the pipe string for applying a fastener to secure the control line to the pipe string.
    Type: Application
    Filed: April 26, 2005
    Publication date: August 25, 2005
    Inventors: Jean Buytaert, Luciano Spadoni, Edward Sinclair
  • Patent number: 6889772
    Abstract: A method and apparatus are provided for installing control lines and pipe into a well. The pipe-holding spider that is normally mounted on the rig floor is supportably retained in a vertically movable retainer. The retainer is adapted for controllably elevating the spider above the rig floor when the pipe slips within the spider are not engaged with the outer surface of the pipe string, thereby providing personnel access to a portion of the length of the pipe string below the elevated spider and above the rig floor. Personnel are provided with access to the pipe string for applying a fastener to secure the control line to the pipe string.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: May 10, 2005
    Assignee: Frank's International, Inc.
    Inventors: Jean Buytaert, Luciano Spadoni, Edward Sinclair
  • Publication number: 20040079533
    Abstract: A method and apparatus are provided for installing control lines and pipe into a well. The pipe-holding spider that is normally mounted on the rig floor is supportably retained in a vertically movable retainer. The retainer is adapted for controllably elevating the spider above the rig floor when the pipe slips within the spider are not engaged with the outer surface of the pipe string, thereby providing personnel access to a portion of the length of the pipe string below the elevated spider and above the rig floor. Personnel are provided with access to the pipe string for applying a fastener to secure the control line to the pipe string.
    Type: Application
    Filed: October 23, 2002
    Publication date: April 29, 2004
    Inventors: Jean Buytaert, Luciano Spadoni, Edward Sinclair
  • Patent number: 6177946
    Abstract: A method and apparatus for processing video and graphics data is accomplished by receiving display data that includes at least one of video data and graphics data. If the display data includes video data, the video data is converted into graphics formatted video data when a first control signal is in a first state. The graphics formatted video data, which is now in a format consistent with the computer monitor (e.g., an RGB video format), is then provided to the computer monitor based on the enablement of the first control signal. Alternately, or in addition to, the graphics data may be provided to the computer monitor. If the display data includes graphics data, i.e., computer generated data for display on a computer monitor, the graphics data is converted into video formatted graphics data when a second control signal is in a second state. In this conversion, the graphics data, which is in a RGB format, is converted into a video format, e.g., a YUV data format.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: January 23, 2001
    Assignee: ATI Technologies, Inc.
    Inventors: David Edward Sinclair, Oswin Hall
  • Patent number: 4186230
    Abstract: A moldable tufted carpet automobile mat, the molded mat and the process of preparing the mat, the moldable automobile mat comprising in combination: a nonwoven fabric or a tufted carpet having a tufted face surface and a back surface; a latex precoat; a thin layer of a stiff, heat-moldable thermoplastic foam of a blend of an elastomer and a resin having a thickness of up to about one-eighth to about three-eighths of an inch.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: January 29, 1980
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Edward A. Sinclair, John M. Kalbfleisch
  • Patent number: 4020026
    Abstract: This invention provides a method of treating rubber in the latex or nonlatex form with polyethylenimine to improve the plasticity and plasticity retention index of the unvulcanized elastomer.
    Type: Grant
    Filed: April 17, 1975
    Date of Patent: April 26, 1977
    Assignee: The Goodyear Tire & Rubber Company
    Inventors: Frits W. Janssen, Edward A. Sinclair